{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T20:45:33Z","timestamp":1789677933604,"version":"4.0.1"},"reference-count":25,"publisher":"Walter de Gruyter GmbH","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_jpm-2016-0075_s_999_w2aab2b8c42b1b7b1aab1c15b1Aa\">\n                  <jats:title>Objective:<\/jats:title>\n                  <jats:p>M\u00fcllerian anomalies are associated with increased risk of miscarriage, intrauterine growth restriction (IUGR) and preterm birth. While a commonly implicated cause is restricted expansion of endometrial cavity, alternatively it could be due to abnormal placentation. We sought to examine clinical and histopathologic factors associated with preterm delivery in women with M\u00fcllerian anomalies.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2016-0075_s_998_w2aab2b8c42b1b7b1aab1c15b2Aa\">\n                  <jats:title>Study design:<\/jats:title>\n                  <jats:p>One hundred and eleven singleton pregnancies in 85 women were analyzed retrospectively. There were 42 pregnancies with bicornaute, 24 with unicornuate, 24 with septate, 19 with didelphys and one each with arcuate and T-shaped uterus. Primary outcomes included gestational age at delivery, placental histopathology, placenta previa and accreta.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2016-0075_s_997_w2aab2b8c42b1b7b1aab1c15b3Aa\">\n                  <jats:title>Results:<\/jats:title>\n                  <jats:p>Twenty-eight (25.2%) of pregnancies were delivered prior to term. Of those, only 14 (50%) were due to preterm labor or preterm premature rupture of membranes (PPROM). Histological evidence of placental malperfusion was present in 22% of all pregnancies and those delivered at an earlier median gestational age [34 (IQR 31\u201337) vs. 37 weeks (IQR 34\u201339); P=0.001]. Malperfusion was more common in preterm than in full term births (46% vs. 14%; P=0.04). Conversely, inflammation was not more common in preterm compared to term deliveries (17.9% vs. 16.9%; P=0.89). Five pregnancies had placenta previa, three of which were complicated by accreta.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2016-0075_s_996_w2aab2b8c42b1b7b1aab1c15b4Aa\">\n                  <jats:title>Conclusion:<\/jats:title>\n                  <jats:p>Placental malperfusion, rather than inflammation, was more commonly associated with preterm births in women with uterine anomalies.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/jpm-2016-0075","type":"journal-article","created":{"date-parts":[[2016,9,19]],"date-time":"2016-09-19T11:36:23Z","timestamp":1474284983000},"page":"45-49","source":"Crossref","is-referenced-by-count":23,"title":["Placental malperfusion as a possible mechanism of preterm birth in patients with M\u00fcllerian anomalies"],"prefix":"10.1515","volume":"45","author":[{"given":"Jovana","family":"Lekovich","sequence":"first","affiliation":[{"name":"Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medicine, 1305 York Avenue, 6 th Floor, New York, NY 10021, United States of America"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua","family":"Stewart","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Weill Cornell Medical Center, 525 East 68 th Street, New York, NY 10021, United States of America"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Anderson","sequence":"additional","affiliation":[{"name":"Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Alabama at Birmingham, 1700 6 th Avenue, South Birmingham, AL 35233, United States of America"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erin","family":"Niemasik","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Weill Cornell Medical Center, 525 East 68 th Street, New York, NY 10021, United States of America"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nigel","family":"Pereira","sequence":"additional","affiliation":[{"name":"Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medicine, 1305 York Avenue, 6 th Floor, New York, NY 10021, United States of America"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Chasen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Weill Cornell Medical Center, 525 East 68 th Street, New York, NY 10021, United States of America"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2016,9,17]]},"reference":[{"key":"2023033123464359548_j_jpm-2016-0075_ref_001_w2aab2b8c42b1b7b1ab2ab1Aa","doi-asserted-by":"crossref","unstructured":"Acien P. Embryological observations on the female genital tract. Hum Reprod. 1992;7:437.","DOI":"10.1093\/oxfordjournals.humrep.a137666"},{"key":"2023033123464359548_j_jpm-2016-0075_ref_002_w2aab2b8c42b1b7b1ab2ab2Aa","doi-asserted-by":"crossref","unstructured":"American Fertility Society. 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