{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T02:35:53Z","timestamp":1791772553470,"version":"4.3.4"},"reference-count":32,"publisher":"Walter de Gruyter GmbH","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background:<\/jats:title><jats:p>Published data on breast milk feeding in infants suffering from inherited metabolic disorders (IMDs) other than phenylketonuria (PKU) are limited and described outcome is variable.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective:<\/jats:title><jats:p>We aimed to evaluate retrospectively whether breastfeeding and\/or breast milk feeding are feasible in infants with IMDs including organic acidemias, fatty acid oxidation disorders, urea cycle disorders, aminoacidopathies or disorders of galactose metabolism.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p>Data on breastfeeding and breast milk feeding as well as monitoring and neurological outcome were collected retrospectively from our database of patients with the mentioned IMD, who were followed in our metabolic center within the last 10 years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>Twenty patients were included in the study, who were either breast fed on demand or received expressed breast milk. All the infants were evaluated clinically and biochemically at 2\u20134-week intervals, with weight gain as the leading parameter to determine metabolic control. Good metabolic control and adequate neurological development were achieved in all patients but one, who experienced the only metabolic crisis observed within the study period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p>Breast milk feeding with close clinical and biochemical monitoring is feasible in most IMD and should be considered as it offers nutritional and immunological benefits.<\/jats:p><\/jats:sec>","DOI":"10.1515\/jpm-2016-0205","type":"journal-article","created":{"date-parts":[[2016,8,26]],"date-time":"2016-08-26T08:30:45Z","timestamp":1472200245000},"source":"Crossref","is-referenced-by-count":11,"title":["Breast milk feeding in infants with inherited metabolic disorders other than phenylketonuria \u2013 a 10-year single-center experience"],"prefix":"10.1515","volume":"45","author":[{"given":"Karin","family":"Pichler","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miriam","family":"Michel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuela","family":"Zlamy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabine","family":"Scholl-Buergi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabeth","family":"Ralser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monika","family":"J\u00f6rg-Streller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Karall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","reference":[{"key":"ref81","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1007\/s10545-005-0457-3","article-title":"Breastfeeding experience in inborn errors of metabolism other than phenylketonuria","volume":"28","year":"2005","journal-title":"J Inherit Metab Dis"},{"key":"ref321","first-page":"1","volume":"23","year":"2000","journal-title":"Breast feeding in metabolic disease: how successful is this?"},{"key":"ref251","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1111\/j.1651-2227.1999.tb01151.x","article-title":"Breastfeeding in phenylketonuria","volume":"88","year":"1999","journal-title":"Acta Paediatr Suppl"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1089\/bfm.2013.0092","article-title":"Breastfeeding infants with phenylketonuria in the united states and canada","volume":"9","year":"2014","journal-title":"Breastfeed Med"},{"key":"ref91","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1007\/s10545-006-0332-x","article-title":"Breast feeding in IMD","volume":"29","year":"2006","journal-title":"J Inherit Metab Dis"},{"key":"ref221","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1007\/BF01802044","article-title":"The management of breast feeding among infants with phenylketonuria","volume":"12","year":"1989","journal-title":"J Inherit Metab Dis"},{"key":"ref261","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1007\/s10545-005-0457-3","article-title":"Breastfeeding experience in inborn errors of metabolism other than phenylketonuria","volume":"28","year":"2005","journal-title":"J Inherit Metab Dis"},{"key":"ref101","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1007\/s10545-005-0255-y","article-title":"Breast feeding in organic acidaemias","volume":"29","year":"2006","journal-title":"J Inherit Metab Dis"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1007\/BF01802044","article-title":"The management of breast feeding among infants with phenylketonuria","volume":"12","year":"1989","journal-title":"J Inherit Metab Dis"},{"key":"ref171","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1097\/MPG.0000000000000873","article-title":"Breastfeeding duration \u2013 early weaning: Do we sufficiently consider the risk factors?","volume":"61","year":"2015","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"ref151","first-page":"448","article-title":"Vademecum meatbolicum. Manual of metabolic paediatrics","volume":"5","year":"2000","journal-title":"J Inherit Metab Dis"},{"key":"ref241","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1089\/bfm.2013.0092","article-title":"Breastfeeding infants with phenylketonuria in the united states and canada","volume":"9","year":"2014","journal-title":"Breastfeed Med"},{"key":"ref301","doi-asserted-by":"crossref","first-page":"S323","DOI":"10.1007\/s10545-008-0903-0","article-title":"Amino acids in CSF and plasma in hyperammonaemic coma due to arginase1 deficiency","volume":"31","year":"2008","journal-title":"J Inherit Metab Dis"},{"key":"ref141","first-page":"1","volume":"23","year":"2000","journal-title":"Breast feeding in metabolic disease: how successful is this?"},{"key":"ref311","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s10545-004-0001-x","article-title":"Abstracts \u2013 SSIEM 42st annual symposium, paris, france, 6\u20139 september, 2005","volume":"28","year":"2005","journal-title":"J Inherit Metab Dis"},{"key":"ref231","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.pedn.2011.03.015","article-title":"Breast-feeding success among infants with phenylketonuria","volume":"27","year":"2012","journal-title":"J Pediatr Nurs"},{"key":"ref131","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s10545-004-0001-x","article-title":"Abstracts \u2013 SSIEM 42st annual symposium, paris, france, 6\u20139 september, 2005","volume":"28","year":"2005","journal-title":"J Inherit Metab Dis"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1093\/jn\/135.5.1304","article-title":"Human-milk glycans that inhibit pathogen binding protect breast-feeding infants against infectious diarrhea","volume":"135","year":"2005","journal-title":"J Nutr"},{"key":"ref331","first-page":"448","article-title":"Vademecum meatbolicum. Manual of metabolic paediatrics","volume":"5","year":"2000","journal-title":"J Inherit Metab Dis"},{"key":"ref351","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1097\/MPG.0000000000000873","article-title":"Breastfeeding duration \u2013 early weaning: Do we sufficiently consider the risk factors?","volume":"61","year":"2015","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"ref21","volume":"Vols. 6\u20138","year":"2002","journal-title":"Breastfeeding in IEOM other than PKU"},{"key":"ref111","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/s13023-015-0236-7","article-title":"Clinical outcome, biochemical and therapeutic follow-up in 14 austrian patients with long-chain 3-hydroxy acyl coa dehydrogenase deficiency (LCHADD)","volume":"10","year":"2015","journal-title":"Orphanet J Rare Dis"},{"key":"ref281","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1007\/s10545-005-0255-y","article-title":"Breast feeding in organic acidaemias","volume":"29","year":"2006","journal-title":"J Inherit Metab Dis"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1111\/j.1651-2227.1999.tb01151.x","article-title":"Breastfeeding in phenylketonuria","volume":"88","year":"1999","journal-title":"Acta Paediatr Suppl"},{"key":"ref271","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1007\/s10545-006-0332-x","article-title":"Breast feeding in IMD","volume":"29","year":"2006","journal-title":"J Inherit Metab Dis"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1111\/j.1651-2227.1994.tb13059.x","article-title":"Faecal short chain fatty acids in breast-fed and formula-fed babies","volume":"83","year":"1994","journal-title":"Acta Paediatr"},{"key":"ref211","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1111\/j.1651-2227.1994.tb13059.x","article-title":"Faecal short chain fatty acids in breast-fed and formula-fed babies","volume":"83","year":"1994","journal-title":"Acta Paediatr"},{"key":"ref191","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1093\/jn\/135.5.1304","article-title":"Human-milk glycans that inhibit pathogen binding protect breast-feeding infants against infectious diarrhea","volume":"135","year":"2005","journal-title":"J Nutr"},{"key":"ref291","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/s13023-015-0236-7","article-title":"Clinical outcome, biochemical and therapeutic follow-up in 14 austrian patients with long-chain 3-hydroxy acyl coa dehydrogenase deficiency (LCHADD)","volume":"10","year":"2015","journal-title":"Orphanet J Rare Dis"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.pedn.2011.03.015","article-title":"Breast-feeding success among infants with phenylketonuria","volume":"27","year":"2012","journal-title":"J Pediatr Nurs"},{"key":"ref121","doi-asserted-by":"crossref","first-page":"S323","DOI":"10.1007\/s10545-008-0903-0","article-title":"Amino acids in CSF and plasma in hyperammonaemic coma due to arginase1 deficiency","volume":"31","year":"2008","journal-title":"J Inherit Metab Dis"},{"key":"ref201","volume":"Vols. 6\u20138","year":"2002","journal-title":"Breastfeeding in IEOM other than PKU"}],"container-title":["Journal of Perinatal Medicine"],"original-title":[],"link":[{"URL":"http:\/\/www.degruyter.com\/view\/j\/jpme.2017.45.issue-3\/jpm-2016-0205\/jpm-2016-0205.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/jpm-2016-0205\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,22]],"date-time":"2021-04-22T01:33:45Z","timestamp":1619055225000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/jpm-2016-0205\/html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1,1]]},"references-count":32,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.1515\/jpm-2016-0205","relation":{},"ISSN":["1619-3997","0300-5577"],"issn-type":[{"value":"1619-3997","type":"electronic"},{"value":"0300-5577","type":"print"}],"subject":[],"published":{"date-parts":[[2017,1,1]]}}}