{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T17:05:10Z","timestamp":1790787910597,"version":"4.1.0"},"reference-count":28,"publisher":"Walter de Gruyter GmbH","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,7,26]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_jpm-2016-0305_s_999_w2aab3b7b2b1b6b1aab1c16b1Aa\">\n                  <jats:title>Aim:<\/jats:title>\n                  <jats:p>\n                     <jats:italic>Ureaplasma parvum, Ureaplasma urealyticum<\/jats:italic> and <jats:italic>Mycoplasma hominis<\/jats:italic> are also known as genital mycoplasmas. Acute chorioamnionitis is an inflammation of the placenta associated with miscarriage. We retrospectively evaluated a possible association between genital mycoplasmas detection, acute chorioamnionitis and fetal pneumonia from second and third trimester spontaneous abortions.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2016-0305_s_998_w2aab3b7b2b1b6b1aab1c16b2Aa\">\n                  <jats:title>Methods:<\/jats:title>\n                  <jats:p>One hundred and thirty placenta and fetal lung samples were evaluated for histological examination. The placenta samples, along with corresponding fetal tracheo-bronchial aspirates, also underwent bacterial and fungal culture and real-time polymerase chain reaction (PCR) assay for the detection of genital mycoplasmas.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2016-0305_s_997_w2aab3b7b2b1b6b1aab1c16b3Aa\">\n                  <jats:title>Results:<\/jats:title>\n                  <jats:p>Acute chorioamnionitis and pneumonia were diagnosed in 80\/130 (61.5%) and 22\/130 (16.9%) samples, respectively. Among samples positive for acute chorioamnionitis, the proportion of samples positive by real-time PCR and\/or culture, was significantly higher than that of negative controls [54\/80 (67.5%) vs. 26\/80 (32.5%); P&lt;0.001]. <jats:italic>Ureaplasma parvum<\/jats:italic> detection was significantly associated with acute chorioamnionitis compared to controls [9\/11 (81.8%) vs. 2\/11 (18.2%); P=0.019], as well as <jats:italic>U. urealyticum<\/jats:italic> [6\/7 (85.7%) vs. 1\/7 (14.3%); P=0.039]. Among tracheo-bronchial aspirates from abortions with pneumonia, the proportion of real-time PCR and\/or culture positive samples was significantly higher than that of controls [13\/22 (59.1%) vs. 9\/22 (40.9%); P=0.029].<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2016-0305_s_996_w2aab3b7b2b1b6b1aab1c16b4Aa\">\n                  <jats:title>Conclusions:<\/jats:title>\n                  <jats:p>A strong association was found between acute histologic chorioamnionitis and microbial invasion with <jats:italic>U. parvum<\/jats:italic> and\/or <jats:italic>U. urealyticum<\/jats:italic>.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/jpm-2016-0305","type":"journal-article","created":{"date-parts":[[2017,6,2]],"date-time":"2017-06-02T13:19:57Z","timestamp":1496409597000},"page":"503-508","source":"Crossref","is-referenced-by-count":33,"title":["Association between genital mycoplasmas, acute chorioamnionitis and fetal pneumonia in spontaneous abortions"],"prefix":"10.1515","volume":"46","author":[{"given":"Maria Agnese","family":"Latino","sequence":"first","affiliation":[{"name":"Department of Laboratory Medicine , Unit of Bacteriology, Citt\u00e0 della Salute e della Scienza , Turin , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Botta","sequence":"additional","affiliation":[{"name":"Fetal and Maternal Pathology , Department of Pathology, OIRM\/Sant\u2019 Anna, Citt\u00e0 della Salute e della Scienza , Turin , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Badino","sequence":"additional","affiliation":[{"name":"Fetal and Maternal Pathology , Department of Pathology, OIRM\/Sant\u2019 Anna, Citt\u00e0 della Salute e della Scienza , Turin , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela De","family":"Maria","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine , Unit of Bacteriology, Citt\u00e0 della Salute e della Scienza , Turin , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annalisa","family":"Petrozziello","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine , Unit of Bacteriology, Citt\u00e0 della Salute e della Scienza , Turin , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Sensini","sequence":"additional","affiliation":[{"name":"Former Professor of Microbiology , University of Perugia , Perugia , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8689-7028","authenticated-orcid":false,"given":"Christian","family":"Leli","sequence":"additional","affiliation":[{"name":"Unit of Microbiology and Virology , University Hospital of Parma , Via Gramsci 14 , 43126 Parma , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2017,5,25]]},"reference":[{"key":"2021021321400048062_j_jpm-2016-0305_ref_001_w2aab3b7b2b1b6b1ab2b1b1Aa","doi-asserted-by":"crossref","unstructured":"Waites KB, Katz B, Schelonka RL. 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