{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T20:37:18Z","timestamp":1785530238599,"version":"3.56.0"},"reference-count":50,"publisher":"Walter de Gruyter GmbH","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,2,23]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"j_jpm-2017-0006_s_999\"><jats:title id=\"d4759861e34896\">Objective:<\/jats:title><jats:p>To compare the results of pulse oximetry screening for critical congenital heart disease (CCHD) in newborn infants performed at &lt;24 h and &gt;24 h following.<\/jats:p><\/jats:sec><jats:sec id=\"j_jpm-2017-0006_s_998\"><jats:title id=\"d4759861e34904\">Method:<\/jats:title><jats:p>Measurements were taken for each group at &lt;24 h and &gt;24 h following birth. Echocardiography was performed if the SpO2 readings remained abnormal results.<\/jats:p><\/jats:sec><jats:sec id=\"j_jpm-2017-0006_s_997\"><jats:title id=\"d4759861e34912\">Results:<\/jats:title><jats:p>A total of 4518 newborns were included in this prospective descriptive study. Of these, 2484 (60.3%) were delivered vaginally and 1685 (39.7%) by cesarean section. Median time points of the screening were 25.4 (25.3\u201325.5) vs. 17.3 (12.2\u201322.4) hours after birth. In 4109 infants screened 24 h after birth, the mean pre- and postductal oxygen saturations (SpO2) were 96.5\u00b11.99 and 97.7\u00b11.98, while 127 infants screened within 24 h of mean preductal and postductal SpO2 were 91.33\u00b12.64 and 94.0\u00b14.44. No CCHD was detected during the study period. Pulse oximetry screening was false positive for CCHD in 9 of 4109 infants (0.02%); of these, six infants were referred to pediatric cardiology and three cases were diagnosed as other significant, non-cardiac pathology. There were two cases with AVSD (atrioventricular septal defect, three cases with ventricular septal defect (VSD), and one case with patent ductus arteriosus (PDA).<\/jats:p><\/jats:sec><jats:sec id=\"j_jpm-2017-0006_s_996\"><jats:title id=\"d4759861e34920\">Conclusions:<\/jats:title><jats:p>Saturation values are different between &lt;24-h and &gt;24-h neonates in pulse oximetry screening. The screening in this study identified infants with other important pathologies, this forms an added value as an assessment tool for newborn infants.<\/jats:p><\/jats:sec>","DOI":"10.1515\/jpm-2017-0006","type":"journal-article","created":{"date-parts":[[2017,6,30]],"date-time":"2017-06-30T08:39:48Z","timestamp":1498811988000},"page":"203-207","source":"Crossref","is-referenced-by-count":8,"title":["Critical congenital heart disease screening with a pulse oximetry in neonates"],"prefix":"10.1515","volume":"46","author":[{"given":"\u015eahin","family":"Hamil\u00e7\u0131kan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emrah","family":"Can","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","reference":[{"key":"ref401","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1007\/s00246-013-0692-6","article-title":"Regional implementation of newborn screening for critical congenital heart disease screening in Abu Dhabi","volume":"34","year":"2013","journal-title":"Pediatr Cardiol"},{"key":"ref241","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1016\/S0140-6736(14)60198-7","article-title":"Pulse oximetry with clinical assessment to screen for congenital heart disease in neonates in China: a prospective study","volume":"384","year":"2014","journal-title":"Lancet"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1001\/archpedi.162.10.969","article-title":"Missed diagnosis of critical congenital heart disease","volume":"162","year":"2008","journal-title":"Arch Pediatr Adolesc Med"},{"key":"ref471","first-page":"1","article-title":"Pulse oximetry as a screening test for congenital heart defects in newborn infants: a test accuracy study with evaluation of acceptability and cost-effectiveness","volume":"16","year":"2012","journal-title":"Health Technol Assess"},{"key":"ref81","doi-asserted-by":"crossref","first-page":"e314","DOI":"10.1542\/peds.2013-0269","article-title":"Results from the New Jersey statewide critical congenital heart defects screening program","volume":"132","year":"2013","journal-title":"Pediatrics"},{"key":"ref311","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1136\/archdischild-2014-307691","article-title":"Timing of diagnosis affects mortality in critical congenital heart disease","volume":"101","year":"2016","journal-title":"Arch Dis Child"},{"key":"ref211","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1002\/bdra.23165","article-title":"Hospitalizations, costs, and mortality among infants with critical congenital heart disease: how important is timely detection?","volume":"97","year":"2013","journal-title":"Birth Defects Res A Clin Mol Teratol."},{"key":"ref61","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1136\/archdischild-2014-307691","article-title":"Timing of diagnosis affects mortality in critical congenital heart disease","volume":"101","year":"2016","journal-title":"Arch Dis Child"},{"key":"ref121","doi-asserted-by":"crossref","first-page":"S11","DOI":"10.1016\/S0378-3782(14)50004-7","article-title":"U.S. international efforts on critical congenital heart disease screening: can we have a uniform recommendation for Europe?","volume":"90","year":"2014","journal-title":"Early Hum Dev."},{"key":"ref221","first-page":"1","article-title":"Pulse oximetry as a screening test for congenital heart defects in newborn infants: a test accuracy study with evaluation of acceptability and cost-effectiveness","volume":"16","year":"2012","journal-title":"Health Technol Assess"},{"key":"ref101","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1542\/peds.2011-3211","article-title":"Section on Cardiology and Cardiac Surgery Executive Committee. 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