{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T10:22:34Z","timestamp":1769509354945,"version":"3.49.0"},"reference-count":29,"publisher":"Walter de Gruyter GmbH","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,12,19]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_jpm-2018-0086_s_999_w2aab3b7c64b1b6b1aab1c16b1Aa\">\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>Morbidly adherent placenta (MAP) is a clinical condition the prevalance of which is steadily increasing. It is described as the invasion of the placenta into the uterine wall through the myometrium and beyond. Several studies have shown that intercellular adhesion molecule-1 (ICAM-1) increases the invasion capability of tumor cells and placental cells. In our study, we investigated the expression of ICAM-1 in MAP cases.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2018-0086_s_998_w2aab3b7c64b1b6b1aab1c16b2Aa\">\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>This is a prospective case-control study. Eighty-nine patients who were diagnosed with MAP and 96 patients, without adherent placenta, as a control group were included in the study. ICAM-1 staining was examined by immuno-histochemical staining in placental samples.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2018-0086_s_997_w2aab3b7c64b1b6b1aab1c16b3Aa\">\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Of the 89 patients in the MAP group, 72 (80.8%) showed positive staining, while 26 (27%) did so in the control group. ICAM-1 positive staining in the MAP group was statistically significantly higher (P=0.03).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2018-0086_s_996_w2aab3b7c64b1b6b1aab1c16b4Aa\">\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>This is the first study investigating the relationship between MAP and ICAM-1 in the literature. In our study, we showed that ICAM-1 expression increased in the MAP group.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/jpm-2018-0086","type":"journal-article","created":{"date-parts":[[2018,7,12]],"date-time":"2018-07-12T23:20:08Z","timestamp":1531437608000},"page":"45-49","source":"Crossref","is-referenced-by-count":4,"title":["Relationship between intercellular adhesion molecule-1 and morbidly adherent placenta"],"prefix":"10.1515","volume":"47","author":[{"given":"Engin","family":"Korkmazer","sequence":"first","affiliation":[{"name":"Health Sciences University , Department of Gynecology and Obstetrics , Bursa , Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rampia","family":"Nizam","sequence":"additional","affiliation":[{"name":"Health Sciences University , Department of Gynecology and Obstetrics , Bursa , Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emine","family":"Arslan","sequence":"additional","affiliation":[{"name":"Hitit University , Department of Gynecology and Obstetrics , \u00c7orum , Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00d6zg\u00fcr","family":"Akkurt","sequence":"additional","affiliation":[{"name":"Health Sciences University , Department of Gynecology and Obstetrics , Bursa , Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2018,7,11]]},"reference":[{"key":"2021021321162353915_j_jpm-2018-0086_ref_001_w2aab3b7c64b1b6b1ab2b2b1Aa","doi-asserted-by":"crossref","unstructured":"Belfort MA, Shamshirsaz AA, Fox KA. 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