{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T07:23:26Z","timestamp":1790666606474,"version":"4.1.0"},"reference-count":14,"publisher":"Walter de Gruyter GmbH","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,2,25]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_jpm-2018-0149_s_999_w2aab3b7c44b1b6b1aab1c17b1Aa\">\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Peripartal hysterectomy (PH) is a challenging surgical procedure with elevated maternal morbidity.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2018-0149_s_998_w2aab3b7c44b1b6b1aab1c17b2Aa\">\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>From 2004 to 2016, 41 emergency PHs were performed at the tertiary care center of the Department of Gynecology and Obstetrics at University Hospital Ulm. In our retrospective analysis, the incidence of PH in our hospital was 12.8 per 10,000 deliveries with a maternal mortality of 2.4%. PH followed in 80.5% after cesarean section (c-section). Underlying causes\/indications for PH were abnormal placentation (53.7%; n=22), uterine atony (26.8%; n=11), uterine lacerations (14.6%; n=6) and in rare cases uterine infection (4.9%; n=2). The median number of transfused products was 11 packed red blood cells (range 0\u201355 products), 10 fresh frozen plasma units (range 1\u201343) and two platelet concentrates (0\u201316).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2018-0149_s_997_w2aab3b7c44b1b6b1aab1c17b3Aa\">\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Loss of blood as estimated by surgeons was significantly correlated with actual transfused blood volume (P&lt;0.001). Clinically relevant intra- and\/or postoperative complications occurred in 53.7% of patients (n=22). Abnormal placentation was the leading cause for PH with an increased incidence during the last 10 years presumptively representing the elevated rate of c-sections.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2018-0149_s_996_w2aab3b7c44b1b6b1aab1c17b4Aa\">\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>PH goes along with increased rates of blood product transfusions independently of indication for surgery and has a high morbidity with a major complication rate of more than 50%. Prepartal assessment of risk factors like abnormal invasive placenta are crucial for reducing maternal morbidity.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/jpm-2018-0149","type":"journal-article","created":{"date-parts":[[2018,9,4]],"date-time":"2018-09-04T09:01:51Z","timestamp":1536051711000},"page":"169-175","source":"Crossref","is-referenced-by-count":9,"title":["Emergency peripartal hysterectomy \u2013 a single-center analysis of the last 13 years at a tertiary perinatal care unit"],"prefix":"10.1515","volume":"47","author":[{"given":"Amelie","family":"de Gregorio","sequence":"first","affiliation":[{"name":"Department of Gynecology and Obstetrics , University Hospital Ulm , Ulm , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas W.P.","family":"Friedl","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics , University Hospital Ulm , Ulm , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Scholz","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics , University Hospital Ulm , Ulm , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang","family":"Janni","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics , University Hospital Ulm , Ulm , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florian","family":"Ebner","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics , HELIOS Amper Hospital Dachau , Dachau , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0037-127X","authenticated-orcid":false,"given":"Nikolaus","family":"de Gregorio","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics , University Hospital Ulm , Ulm , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2018,9,4]]},"reference":[{"key":"2021021321382457325_j_jpm-2018-0149_ref_001_w2aab3b7c44b1b6b1ab2b1b1Aa","doi-asserted-by":"crossref","unstructured":"Machado LSM. Emergency peripartum hysterectomy: incidence, indications, risk factors and outcome. N Am J Med Sci 2011;3:358\u201361.","DOI":"10.4297\/najms.2011.358"},{"key":"2021021321382457325_j_jpm-2018-0149_ref_002_w2aab3b7c44b1b6b1ab2b1b2Aa","doi-asserted-by":"crossref","unstructured":"Bodelon C, Bernabe-Ortiz A, Schiff MA, Reed SD. Factors associated with peripartum hysterectomy. Obstet Gynecol 2009;114:115\u201323.","DOI":"10.1097\/AOG.0b013e3181a81cdd"},{"key":"2021021321382457325_j_jpm-2018-0149_ref_003_w2aab3b7c44b1b6b1ab2b1b3Aa","doi-asserted-by":"crossref","unstructured":"Glaze S, Ekwalanga P, Roberts G, Lange I, Birch C, Rosengarten A, et al. Peripartum hysterectomy: 1999 to 2006. Obstet Gynecol 2008;111:732\u20138.","DOI":"10.1097\/AOG.0b013e31816569f2"},{"key":"2021021321382457325_j_jpm-2018-0149_ref_004_w2aab3b7c44b1b6b1ab2b1b4Aa","unstructured":"Peripartal haemorrhage, diagnosis and therapy. 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