{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:21:20Z","timestamp":1787761280242,"version":"build-2784847793"},"reference-count":50,"publisher":"Walter de Gruyter GmbH","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,8,27]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:sec id=\"j_jpm-2019-0103_s_999\">\n<jats:title id=\"d11421495e42821\">Background<\/jats:title>\n<jats:p>Obesity in pregnancy is increasing worldwide, reaching epidemic proportions in many countries and frequently creating challenges for obstetricians. We conducted this study to assess the effects of maternal obesity on maternal and perinatal outcomes.<\/jats:p><\/jats:sec>\n<jats:sec id=\"j_jpm-2019-0103_s_998\">\n<jats:title id=\"d11421495e42829\">Methods<\/jats:title>\n<jats:p>A historical cohort study was performed on 16,609 women who delivered singleton babies in a 5-year period (2013\u20132017). Data were retrieved from the Cruces Perinatal Database (CPD) and only women whose prepregnancy body mass index (BMI) was known were included. Women were categorized according to the World Health Organization (WHO) classification: normal weight (BMI 20\u201324.9 kg\/m<jats:sup>2<\/jats:sup>) and obesity (BMI \u2265 30 kg\/m<jats:sup>2<\/jats:sup>). Obstetric, perinatal and neonatal outcomes were compared, and adjusted odds ratios (aORs) and 95% confidence intervals (95% CIs) were calculated using the normal-weight group as the reference.<\/jats:p><\/jats:sec>\n<jats:sec id=\"j_jpm-2019-0103_s_997\">\n<jats:title id=\"d11421495e42843\">Results<\/jats:title>\n<jats:p>Compared to women of normal weight (n = 9778), obese women (n = 2207) had a higher risk of preeclampsia (aOR 2.199, 95% CI: 1.46\u20133.29), rectovaginal group B streptococcus colonization (aOR 1.299, 95% CI: 1.14\u20131.47), induction of labor (aOR 1.593, 95% CI: 1.44\u20131.75), cesarean section (aOR 2.755, 95% CI: 2.46\u20133.08), cesarean section in women with a history of cesarean delivery (aOR 1.409, 95% CI: 1.03\u20131.92), fetal weight \u22654000 g (aOR 2.090, 95% CI: 1.803\u20132.422) and admission to the neonatal intensive care unit (NICU) (aOR 1.341, 95% CI: 1.12\u20131.59). No association was found with preterm birth (aOR 0.936, 95% CI: 0.77\u20131.13), stillbirth (aOR 0.921, 95% CI: 0.41\u20132.02) or neonatal mortality (aOR 2.205, 95% CI: 0.86\u20135.62).<\/jats:p><\/jats:sec>\n<jats:sec id=\"j_jpm-2019-0103_s_996\">\n<jats:title id=\"d11421495e42851\">Conclusion<\/jats:title>\n<jats:p>Maternal obesity is associated with a higher risk of adverse pregnancy and perinatal outcomes. Pregnancy in this population of women should be considered and managed as high risk.<\/jats:p><\/jats:sec>","DOI":"10.1515\/jpm-2019-0103","type":"journal-article","created":{"date-parts":[[2019,5,29]],"date-time":"2019-05-29T09:03:03Z","timestamp":1559120583000},"page":"625-630","source":"Crossref","is-referenced-by-count":74,"title":["Effect of maternal obesity on pregnancy outcomes in women delivering singleton babies: a historical cohort study"],"prefix":"10.1515","volume":"47","author":[{"given":"I\u00f1igo","family":"Melchor","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge","family":"Burgos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"del Campo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amaia","family":"Aiartzaguena","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julieta","family":"Guti\u00e9rrez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Carlos","family":"Melchor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","reference":[{"key":"ref381","doi-asserted-by":"crossref","first-page":"R97","DOI":"10.1530\/REP-16-0495","article-title":"Effects of maternal obesity on placental function and fetal development","volume":"153","year":"2017","journal-title":"Reproduction"},{"key":"ref491","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1097\/AOG.0b013e3182245d49","article-title":"Effect of prepregnancy maternal overweight and obesity on pregnancy outcome","volume":"118","year":"2011","journal-title":"Obstet Gynecol"},{"key":"ref141","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1097\/AOG.0000000000000591","article-title":"Risk of adverse pregnancy outcomes by prepregnancy body mass index: a population-based study to inform prepregnancy weight loss counseling","volume":"125","year":"2015","journal-title":"Obstet Gynecol"},{"key":"ref361","first-page":"640291","article-title":"Maternal obesity and occurrence of fetal macrosomia: a systematic review and meta-analysis","volume":"2014","year":"2014","journal-title":"Biomed Res Int"},{"key":"ref331","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1111\/j.1467-789X.2007.00397.x","article-title":"Maternal obesity and risk of cesarean delivery: a meta-analysis","volume":"8","year":"2007","journal-title":"Obes Rev"},{"key":"ref421","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1097\/AOG.0000000000000591","article-title":"Risk of adverse pregnancy outcomes by prepregnancy body mass index: a population-based study to inform prepregnancy weight loss counseling","volume":"125","year":"2015","journal-title":"Obstet Gynecol"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1111\/obr.12489","article-title":"Maternal body mass index and post-term birth: a systematic review and meta-analysis","volume":"18","year":"2017","journal-title":"Obes Rev"},{"key":"ref181","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1097\/AOG.0000000000002775","article-title":"Neonatal morbidity in the offspring of obese women without hypertension or diabetes","volume":"132","year":"2018","journal-title":"Obstet Gynecol"},{"key":"ref231","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.ajog.2018.06.006","article-title":"A conceptual framework for the impact of obesity on risk of cesarean delivery","volume":"219","year":"2018","journal-title":"Am J Obstet Gynecol"},{"key":"ref471","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1097\/01.EDE.0000059921.71494.D1","article-title":"Ray JG. 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studies","volume":"14","year":"2013","journal-title":"Obes Rev"},{"key":"ref251","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1111\/j.1600-0412.2011.01331.x","article-title":"Mortality in infants of obese mothers: is risk modified by mode of delivery?","volume":"91","year":"2012","journal-title":"Acta Obstet Gynecol Scand"},{"key":"ref431","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1097\/AOG.0000000000001465","article-title":"Obstetric and neonatal risks among obese women without chronic disease","volume":"128","year":"2016","journal-title":"Obstet Gynecol"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"308","DOI":"10.3109\/14767058.2011.575905","article-title":"Abnormal maternal body mass index and obstetric and neonatal outcome","volume":"25","year":"2012","journal-title":"J Matern Fetal Neonatal Med"},{"key":"ref461","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1097\/AOG.0000000000002775","article-title":"Neonatal morbidity in the 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