{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T16:30:18Z","timestamp":1759336218236},"reference-count":16,"publisher":"Walter de Gruyter GmbH","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,10,25]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_jpm-2019-0291_s_999_w2aab3b7c65b1b6b1aab1c15b1Aa\">\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>The aim of this study was to compare transabdominal and transcervical chorionic villus sampling (CVS) as well as amniocentesis (AC) with respect to their rates of premature delivery and fetal growth restriction.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2019-0291_s_998_w2aab3b7c65b1b6b1aab1c15b2Aa\">\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We retrospectively evaluated the mentioned procedures of invasive prenatal testing performed in a single center between 2001 and 2016. Seven hundred and ninety-nine cases of AC and 719 cases of CVS were included, of which 400 were performed transvaginally. Only singleton pregnancies with a normal karyotype and delivery after 24\u2009+\u20090 weeks of gestation were included. Fetal growth restriction was defined as birth weight below the 10<jats:sup>th<\/jats:sup> percentile. Premature delivery was defined as delivery before 37\u2009+\u20090 weeks of gestation. Data were compared to a control group without an invasive procedure.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2019-0291_s_997_w2aab3b7c65b1b6b1aab1c15b3Aa\">\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The frequency of premature delivery was 8.5% after transabdominal CVS, 6.3% after transcervical CVS and 10.5% after AC as compared to 10.8% in the control group. The frequency of fetal growth restriction was 8.2% after transabdominal CVS 6.8% after transcervical CVS and 8.4% after AC as compared to 9.7% in the control group.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2019-0291_s_996_w2aab3b7c65b1b6b1aab1c15b4Aa\">\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Our study supports that the three different methods of invasive prenatal testing do not lead to a higher risk of either premature delivery or fetal growth restriction when compared to controls. We found no difference in risk profile among the three techniques.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/jpm-2019-0291","type":"journal-article","created":{"date-parts":[[2019,9,10]],"date-time":"2019-09-10T09:02:33Z","timestamp":1568106153000},"page":"811-816","source":"Crossref","is-referenced-by-count":2,"title":["Procedure related risk of premature delivery and fetal growth reduction following amniocentesis, transcervical and transabdominal chorionic villus sampling: a retrospective study"],"prefix":"10.1515","volume":"47","author":[{"given":"Julia","family":"Zimmer","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology , University Hospital M\u00fcnster , Albert-Schweitzer Campus 1, Geb\u00e4ude A1 , 48149 M\u00fcnster , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ralf","family":"Schmitz","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , University Hospital M\u00fcnster , M\u00fcnster , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mareike","family":"M\u00f6llers","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , University Hospital M\u00fcnster , M\u00fcnster , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kerstin","family":"Hammer","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , University Hospital M\u00fcnster , M\u00fcnster , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria K.","family":"Falkenberg","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , University Hospital M\u00fcnster , M\u00fcnster , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janina","family":"Braun","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , University Hospital M\u00fcnster , M\u00fcnster , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rene","family":"Schmidt","sequence":"additional","affiliation":[{"name":"Institute of Biostatistics and Clinical Research , University of M\u00fcnster , M\u00fcnster , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthias","family":"Borowski","sequence":"additional","affiliation":[{"name":"Institute of Biostatistics and Clinical Research , University of M\u00fcnster , M\u00fcnster , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes","family":"Steinhard","sequence":"additional","affiliation":[{"name":"Department of Fetal Cardiology, Heart and Diabetes Center North Rhine-Westphalia , Bad Oeynhausen , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helen A.","family":"K\u00f6ster","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , University Hospital M\u00fcnster , M\u00fcnster , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Walter","family":"Klockenbusch","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , University Hospital M\u00fcnster , M\u00fcnster , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathrin","family":"Oelmeier de Murcia","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , University Hospital M\u00fcnster , M\u00fcnster , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2019,9,10]]},"reference":[{"key":"2021021322421502993_j_jpm-2019-0291_ref_001_w2aab3b7c65b1b6b1ab2b1b1Aa","doi-asserted-by":"crossref","unstructured":"Alfirevic Z, Sundberg K, Brigham S. 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