{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T18:44:25Z","timestamp":1760985865187},"reference-count":20,"publisher":"Walter de Gruyter GmbH","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,4,28]]},"abstract":"Abstract<\/jats:title>Objective<\/jats:title>The aim of this study was to compare position-related changes in fetal middle cerebral artery (MCA) Doppler pulsatility indices (PI).<\/jats:p><\/jats:sec>Methods<\/jats:title>A prospective study of 41 women with conditions associated with placental-pathology (chronic hypertension, pregestational diabetes, and abnormal analytes) and 34 women without those conditions was carried out. Fetal MCA Doppler velocity flow waveforms were obtained in maternal supine and left lateral decubitus positions. MCA PI \u0394 was calculated by subtracting the PI in the supine position from the PI in the left lateral position. Secondary outcomes included a composite of adverse perinatal outcomes (fetal growth restriction, oligohydramnios, and preeclampsia). \u03c72<\/jats:sup>and Studentt<\/jats:italic>-tests and repeated-measures analysis of variance were used.<\/jats:p><\/jats:sec>Results<\/jats:title>MCA PI \u0394 was significantly less for high-risk pregnant women ([P\u2009=\u20090.03]: high risk, left lateral PI, 1.90\u2009\u00b1\u20090.45 vs. supine PI, 1.88\u2009\u00b1\u20090.46 [\u0394\u2009=\u20090.02]; low risk, left lateral PI, 1.90\u2009\u00b1\u20090.525 vs. supine PI, 1.68\u2009\u00b1\u20090.40 [\u0394\u2009=\u20090.22]). MCA PI \u0394 was not significantly different between women who had a composite adverse outcome and women who did not have a composite adverse outcome (P\u2009=\u20090.843).<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Our preliminary study highlights differences in position-related changes in fetal MCA PI between high-risk and low-risk pregnancies. These differences could reflect an attenuated ability of women with certain risk factors to respond to physiologic stress.<\/jats:p><\/jats:sec>","DOI":"10.1515\/jpm-2019-0399","type":"journal-article","created":{"date-parts":[[2020,3,31]],"date-time":"2020-03-31T14:15:12Z","timestamp":1585664112000},"page":"317-321","source":"Crossref","is-referenced-by-count":5,"title":["The effect of maternal position on fetal middle cerebral artery Doppler indices and its association with adverse perinatal outcomes: a pilot study"],"prefix":"10.1515","volume":"48","author":[{"given":"Rodney","family":"McLaren","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Maimonides Medical Center, Brooklyn NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bharati","family":"Kalgi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Maimonides Infants and Children\u2019s Hospital, Brooklyn, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chima","family":"Ndubizu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, University of Miami School of Medicine\/Jackson Memorial Hospital, Miami, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Homel","sequence":"additional","affiliation":[{"name":"Albert Einstein College of Medicine, Bronx, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shoshana","family":"Haberman","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Maimonides Medical Center, Brooklyn NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Howard","family":"Minkoff","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Maimonides Medical Center, Brooklyn NY, 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