{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T02:36:40Z","timestamp":1770518200685,"version":"3.49.0"},"reference-count":12,"publisher":"Walter de Gruyter GmbH","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,6,25]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"j_jpm-2019-0429_s_999_w2aab3b7c13b1b6b1aab1c16b1Aa\"><jats:title>Background<\/jats:title><jats:p>Metabolic acidosis, measured in arterial umbilical cord blood at birth, is the most accepted definition of birth asphyxia. The aim of the study was to investigate the rates of metabolic acidosis across the entire range of Apgar score values (0\u201310) at 1, 5, and 10 min in term infants.<\/jats:p><\/jats:sec><jats:sec id=\"j_jpm-2019-0429_s_998_w2aab3b7c13b1b6b1aab1c16b2Aa\"><jats:title>Methods<\/jats:title><jats:p>In a population-based Swedish cohort of births between 2008 and 2013, we included 85,076 term (\u226537 weeks) non-malformed infants with information from umbilical arterial blood gas analyses and complete information on Apgar scores (0\u201310) at 1, 5, and 10 min.<\/jats:p><\/jats:sec><jats:sec id=\"j_jpm-2019-0429_s_997_w2aab3b7c13b1b6b1aab1c16b3Aa\"><jats:title>Results<\/jats:title><jats:p>Rates of metabolic acidosis generally decreased with increasing Apgar score values. For Apgar score at 1 min, this decrease was consistent from Apgar score 0 (35%) to Apgar score 10 (0%). For Apgar scores at 5 and 10 min, the decrease was consistent for Apgar score values from 6 to 10.<\/jats:p><\/jats:sec><jats:sec id=\"j_jpm-2019-0429_s_996_w2aab3b7c13b1b6b1aab1c16b4Aa\"><jats:title>Conclusion<\/jats:title><jats:p>Although there is a close association between Apgar score values and rates of metabolic acidosis, Apgar score is not and should not be used as a measure of birth asphyxia.<\/jats:p><\/jats:sec>","DOI":"10.1515\/jpm-2019-0429","type":"journal-article","created":{"date-parts":[[2020,5,26]],"date-time":"2020-05-26T16:09:53Z","timestamp":1590509393000},"page":"514-515","source":"Crossref","is-referenced-by-count":7,"title":["Rates of metabolic acidosis at birth and Apgar score values at 1, 5, and 10 min in term infants: a Swedish cohort study"],"prefix":"10.1515","volume":"48","author":[{"given":"Sven","family":"Cnattingius","sequence":"first","affiliation":[{"name":"Division of Clinical Epidemiology, Department of Medicine Solna, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Johansson","sequence":"additional","affiliation":[{"name":"Division of Clinical Epidemiology, Department of Medicine Solna, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden"},{"name":"Department of Clinical Science and Education, S\u00f6dersjukhuset, Karolinska Institutet, Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neda","family":"Razaz","sequence":"additional","affiliation":[{"name":"Division of Clinical Epidemiology, Department of Medicine Solna, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","reference":[{"key":"ref21","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1001\/jama.2017.0945","article-title":"Association between maternal body mass index in early pregnancy and incidence of cerebral palsy","volume":"317","year":"2017","journal-title":"J Am Med Assoc"},{"key":"ref91","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1001\/jama.2017.0945","article-title":"Association between maternal body mass index in early pregnancy and incidence of cerebral palsy","volume":"317","year":"2017","journal-title":"J Am Med Assoc"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1001\/jamaneurol.2016.6130","article-title":"Maternal body mass index in early pregnancy and risk of epilepsy in offspring","volume":"74","year":"2017","journal-title":"JAMA Neurol"},{"key":"ref81","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.1016\/S0140-6736(14)61135-1","article-title":"Apgar score and the risk of cause-specific infant mortality: a population-based cohort study","volume":"384","year":"2014","journal-title":"Lancet"},{"key":"ref01","first-page":"k207","article-title":"Five and 10 minute Apgar scores and risks of cerebral palsy and epilepsy: population based cohort study in Sweden","volume":"360","year":"2018","journal-title":"Br Med J"},{"key":"ref71","first-page":"k207","article-title":"Five and 10 minute Apgar scores and risks of cerebral palsy and epilepsy: population based cohort study in Sweden","volume":"360","year":"2018","journal-title":"Br Med J"},{"key":"ref111","first-page":"l1656","article-title":"Association between Apgar scores of 7 to 9 and neonatal mortality and morbidity: a population-based cohort study of term infants in Sweden","volume":"365","year":"2019","journal-title":"Br Med J"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.1016\/S0140-6736(14)61135-1","article-title":"Apgar score and the risk of cause-specific infant mortality: a population-based cohort study","volume":"384","year":"2014","journal-title":"Lancet"},{"key":"ref101","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1001\/jamaneurol.2016.6130","article-title":"Maternal body mass index in early pregnancy and risk of epilepsy in offspring","volume":"74","year":"2017","journal-title":"JAMA Neurol"},{"key":"ref41","first-page":"l1656","article-title":"Association between Apgar scores of 7 to 9 and neonatal mortality and morbidity: a population-based cohort study of term infants in Sweden","volume":"365","year":"2019","journal-title":"Br Med J"},{"key":"ref121","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1136\/adc.2006.099846","article-title":"Use of umbilical cord blood gas analysis in the assessment of the newborn","volume":"92","year":"2007","journal-title":"Arch Dis Child-Fetal"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1136\/adc.2006.099846","article-title":"Use of umbilical cord blood gas analysis in the assessment of the newborn","volume":"92","year":"2007","journal-title":"Arch Dis Child-Fetal"}],"container-title":["Journal of Perinatal Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.degruyter.com\/view\/journals\/jpme\/48\/5\/article-p514.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/jpm-2019-0429\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,22]],"date-time":"2021-04-22T01:37:18Z","timestamp":1619055438000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/jpm-2019-0429\/html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,25]]},"references-count":12,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.1515\/jpm-2019-0429","relation":{},"ISSN":["1619-3997","0300-5577"],"issn-type":[{"value":"1619-3997","type":"electronic"},{"value":"0300-5577","type":"print"}],"subject":[],"published":{"date-parts":[[2020,6,25]]}}}