{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T00:49:21Z","timestamp":1771548561560,"version":"3.50.1"},"reference-count":58,"publisher":"Walter de Gruyter GmbH","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,4,28]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"j_jpm-2019-0437_s_999_w2aab3b7c52b1b6b1aab1c17b1Aa\"><jats:title>Background<\/jats:title><jats:p>In monochorionic twin pregnancy, placental anastomosis and inter-twin blood transfusion can result in specific complications, such as twin-twin transfusion syndrome (TTTS) and twin anemia-polycythemia sequence (TAPS). It is well established that adverse outcomes are increased in TTTS, but reports on the neonatal and long-term outcomes of TAPS are lacking. The objective of this study was to evaluate the neonatal and neurodevelopmental outcomes in spontaneous TAPS.<\/jats:p><\/jats:sec><jats:sec id=\"j_jpm-2019-0437_s_998_w2aab3b7c52b1b6b1aab1c17b2Aa\"><jats:title>Methods<\/jats:title><jats:p>The study population consisted of monochorionic twin pregnancies with preterm birth (24\u201337 weeks of gestation) between November 2003 and December 2016 and in which cord blood was taken at the time of delivery. According to the result of hemoglobin in cord blood, the study population was divided into two groups: a spontaneous TAPS group and a control group. Neonatal and neurodevelopmental outcomes were compared between the two groups.<\/jats:p><\/jats:sec><jats:sec id=\"j_jpm-2019-0437_s_997_w2aab3b7c52b1b6b1aab1c17b3Aa\"><jats:title>Results<\/jats:title><jats:p>During the study period, 11 cases were diagnosed as spontaneous TAPS (6.4%). The TAPS group had lower gestational age at delivery and had a higher risk for cesarean delivery. However, neonates with TAPS were not at an increased risk for neonatal mortality and significant neonatal morbidity. In addition, the frequency of severe cerebral lesion during the neonatal period and the risk of cerebral palsy at 2 years of age were not different between the two groups.<\/jats:p><\/jats:sec><jats:sec id=\"j_jpm-2019-0437_s_996_w2aab3b7c52b1b6b1aab1c17b4Aa\"><jats:title>Conclusion<\/jats:title><jats:p>The spontaneous TAPS diagnosed by postnatal diagnostic criteria was not associated with the increased risk of adverse neonatal and neurodevelopmental outcomes. Further studies are needed to evaluate the morbidity of antenatally diagnosed TAPS.<\/jats:p><\/jats:sec>","DOI":"10.1515\/jpm-2019-0437","type":"journal-article","created":{"date-parts":[[2020,3,31]],"date-time":"2020-03-31T14:19:46Z","timestamp":1585664386000},"page":"329-334","source":"Crossref","is-referenced-by-count":4,"title":["Short- and long-term outcomes of preterm spontaneous twin anemia-polycythemia sequence"],"prefix":"10.1515","volume":"48","author":[{"given":"Soo Jin","family":"Han","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seung Mi","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sohee","family":"Oh","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Subeen","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Republic of Korea"},{"name":"Department of Obstetrics and Gynecology, Seoul St. Mary\u2019s Hospital, The Catholic University of Korea, Seoul, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeong Won","family":"Oh","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Republic of Korea"},{"name":"Department of Obstetrics and Gynecology, College of Medicine, Soonchunhyang 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