{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,30]],"date-time":"2022-03-30T16:13:28Z","timestamp":1648656808765},"reference-count":10,"publisher":"Walter de Gruyter GmbH","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,10,25]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_jpem-2020-0278_abs_001_w2aab3b7c30b1b6b1aab1c16b2Aa\">\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>The objectives of this study were to quantify the prescription of oral methergin tablets in a busy Women\u2019s Hospital, assess the stated indications for such prescription and highlight the issues and safety profile of Methergin use especially in the postpartum patient.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpem-2020-0278_abs_002_w2aab3b7c30b1b6b1aab1c16b3Aa\">\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Review of prescription data for oral Methergin and the corresponding annual figures on primary and secondary postpartum hemorrhage.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpem-2020-0278_abs_003_w2aab3b7c30b1b6b1aab1c16b4Aa\">\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Over a period of 5 years, oral Methergin prescriptions for delayed and secondary postpartum hemorrhage constituted less than 1% of the overall prescription in Obstetrics and Gynaecology, which ranged between 1214 and 2085 per year. The numbers were too few to ascertain any relationship with both types of postpartum hemorrhage. Although stated on the relevant Patient Information leaflet, no local or regional guideline on its use exist.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpem-2020-0278_abs_004_w2aab3b7c30b1b6b1aab1c16b5Aa\">\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Specific and random trend monitoring of medications for continuing safety profile, risk benefit issues, or unapproved indication, may help in identifying, preventing and mitigating any medication safety matters. Clinical pharmacists in collaboration with physicians are well placed in conducting such pharmacovigilance activities to improve medication safety.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/jpm-2020-0128","type":"journal-article","created":{"date-parts":[[2020,11,3]],"date-time":"2020-11-03T14:45:13Z","timestamp":1604414713000},"page":"853-855","source":"Crossref","is-referenced-by-count":0,"title":["Pharmaco-vigilance of oral MethylErgometrine prescriptions for delayed and secondary postpartum haemorrhage"],"prefix":"10.1515","volume":"48","author":[{"given":"Abdul Rouf","family":"Pallivalapila","sequence":"first","affiliation":[{"name":"Department of Pharmacy , Women\u2019s Wellness and Research Center , Doha , Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isaac A.","family":"Babarinsa","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Women\u2019s Wellness and Research Center , Doha , Qatar"},{"name":"Weill-Cornell Medical College in Qatar (IAB) , Doha , Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariam","family":"Al-Baloushi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Women\u2019s Wellness and Research Center , Doha , Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed","family":"Moursi","sequence":"additional","affiliation":[{"name":"Department of Pharmacy , Women\u2019s Wellness and Research Center , Doha , Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arabo","family":"Bayo","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Women\u2019s Wellness and Research Center , Doha , Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Binny","family":"Thomas","sequence":"additional","affiliation":[{"name":"Department of Pharmacy , Women\u2019s Wellness and Research Center , Doha , Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahmoud G","family":"Mahmoud Mohd","sequence":"additional","affiliation":[{"name":"Department of Pharmacy , Women\u2019s Wellness and Research Center , Doha , Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2020,8,18]]},"reference":[{"key":"2021021320131973122_j_jpm-2020-0128_ref_001_w2aab3b7c30b1b6b1ab2b1b1Aa","doi-asserted-by":"crossref","unstructured":"Businaro, R. Why we need efficient and careful pharmacovigilance. J Pharmacovigil 2013;1:e110. https:\/\/doi.org\/10.4172\/2329-6887.1000e110.","DOI":"10.4172\/2329-6887.1000e110"},{"key":"2021021320131973122_j_jpm-2020-0128_ref_002_w2aab3b7c30b1b6b1ab2b1b2Aa","unstructured":"Methergin\u00ae. In-packet patient information leaflet. Wehr: Novartis. 2012. Reference ID: 3150408. (T2012)."},{"key":"2021021320131973122_j_jpm-2020-0128_ref_003_w2aab3b7c30b1b6b1ab2b1b3Aa","doi-asserted-by":"crossref","unstructured":"Andersen, B, Andersen, LL, Sorensen, T. Methylergometrine during the early puerperium: a prospective randomized double-blind study. Acta Obstet Gyn Scan 1998;77:54\u20137. https:\/\/doi.org\/10.1080\/00016349808565812.","DOI":"10.1080\/00016349808565812"},{"key":"2021021320131973122_j_jpm-2020-0128_ref_004_w2aab3b7c30b1b6b1ab2b1b4Aa","doi-asserted-by":"crossref","unstructured":"de Labriolle, A, Gen\u00e9e, O, Heggs, LM, Fauchier, L. 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