{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T23:02:50Z","timestamp":1780614170779,"version":"3.54.1"},"reference-count":29,"publisher":"Walter de Gruyter GmbH","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,2,23]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_jpm-2020-0147_abs_001_w2aab3b7c28b1b6b1aab1c15b1Aa\">\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>This study aims to present the termination of pregnancy (TOP) rates and elucidate the decision-making process following a prenatal diagnosis of Trisomy 21 in Turkey.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2020-0147_abs_002_w2aab3b7c28b1b6b1aab1c15b2Aa\">\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>This retrospective single-center study was conducted with 146 pregnant women between January 2016 and December 2019 in a tertiary hospital. Data on maternal characteristics, sonographic findings, indications for chromosome analysis, and educational, religious, and economic factors that can influence the parental decision process were collected.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2020-0147_abs_003_w2aab3b7c28b1b6b1aab1c15b3Aa\">\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The TOP rate of Down syndrome (DS) in our center was 78.8%. We concluded that maternal age, earlier diagnosis, indication for chromosome analysis, and previous pregnancies had no effect on the TOP decision. On the other hand, not having a minor or a major sonographic sign, employed mothers, middle- and high-income families, and families having a secondary or higher education tended to terminate the pregnancy affected by DS at statistically higher rates.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2020-0147_abs_004_w2aab3b7c28b1b6b1aab1c15b4Aa\">\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>There are many studies worldwide investigating the TOP preferences for DS. However, there is limited data about TOP rates and influential factors affecting the decision-making process in Muslim countries. This study contributes by clarifying the factors in the decision-making process and elucidating perspectives about TOP in a Muslim country with a unique status: Turkey.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/jpm-2020-0147","type":"journal-article","created":{"date-parts":[[2020,9,14]],"date-time":"2020-09-14T11:40:34Z","timestamp":1600083634000},"page":"170-177","source":"Crossref","is-referenced-by-count":6,"title":["Termination of pregnancy following a Down Syndrome diagnosis: decision-making process and influential factors in a Muslim but secular country, Turkey"],"prefix":"10.1515","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5307-8149","authenticated-orcid":false,"given":"Duygu","family":"Adiyaman","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Division of Perinatology , Tepecik Training and Research Hospital , Izmir , Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bahar Konuralp","family":"Atakul","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Division of Perinatology , Tepecik Training and Research Hospital , Izmir , Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melda","family":"Kuyucu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Division of Perinatology , Tepecik Training and Research Hospital , Izmir , Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alkim Gulsah","family":"Sahingoz Yildirim","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Division of Perinatology , Tepecik Training and Research Hospital , Izmir , Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Halil Gursoy","family":"Pala","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Division of Perinatology , Tepecik Training and Research Hospital , Izmir , Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2020,9,14]]},"reference":[{"key":"2023040100154848698_j_jpm-2020-0147_ref_001_w2aab3b7c28b1b6b1ab2b1b1Aa","doi-asserted-by":"crossref","unstructured":"Deng, C, Yi, L, Mu, Y, Zhu, J, Qin, Y, Fan, X, et al. 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