{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T20:34:23Z","timestamp":1792182863805,"version":"4.4.0"},"reference-count":18,"publisher":"Walter de Gruyter GmbH","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,1,26]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_jpm-2020-0199_abs_001\">\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>Evaluate the association between urolithiasis during pregnancy and obstetric outcomes outside the context of urological intervention.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2020-0199_abs_002\">\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We conducted a retrospective cohort study of singleton, non-anomalous gestations delivered at 23\u201342\u00a0weeks in California from 2007 to 2011. Maternal outcomes (preterm delivery [early (&lt;32\u00a0weeks) and late (&lt;37\u00a0weeks)], preeclampsia, gestational diabetes, cesarean deliveries, urinary tract infection [UTI] at delivery, chorioamnionitis, endomyometritis, and maternal sepsis) and newborn outcomes (seizure, respiratory distress syndrome, hypoglycemia, jaundice, and neonatal abstinence syndrome [NAS]) were compared using <jats:italic>\u03c7<\/jats:italic>\n                     <jats:sup>2<\/jats:sup>-tests and multivariable logistic regression.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2020-0199_abs_003\">\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A total of 2,013,767 pregnancies met inclusion criteria, of which 5,734 (0.28%) were complicated by urolithiasis. Stone disease during pregnancy was associated with 30% greater odds of each early (aOR 1.30; 95% CI 1.19\u20131.43) and late (aOR 1.29; 95% CI 1.18\u20131.41) preterm delivery. Cesarean delivery, UTI at delivery, gestational hypertension, gestational diabetes, preeclampsia, and sepsis were all significantly positively associated with urolithiasis. Odds of NAS (aOR 2.11; 95% CI 1.27\u20133.51) and jaundice were significantly greater in the neonates of stone-forming patients (aOR 1.08; 95% CI 1.01\u20131.16).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2020-0199_abs_004\">\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Urolithiasis during pregnancy was associated with 30% greater odds of preterm delivery and increased risk of myriad metabolic, hypertensive, and infectious disorders of gestation. Neonates born to stone-forming patients were more than twice as likely to develop neonatal abstinence syndrome but did not have significantly greater odds of complications of prematurity.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/jpm-2020-0199","type":"journal-article","created":{"date-parts":[[2020,11,6]],"date-time":"2020-11-06T16:29:53Z","timestamp":1604680193000},"page":"54-59","source":"Crossref","is-referenced-by-count":7,"title":["Obstetric outcomes of pregnancy complicated by urolithiasis: a retrospective cohort study"],"prefix":"10.1515","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0012-0785","authenticated-orcid":false,"given":"Emily K.","family":"Clennon","sequence":"first","affiliation":[{"name":"Oregon Health & Science University , Departments of Obstetrics and Gynecology and Urology , Portland , OR , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bharti","family":"Garg","sequence":"additional","affiliation":[{"name":"Oregon Health & Science University , Departments of Obstetrics and Gynecology and Urology , Portland , OR , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian D.","family":"Duty","sequence":"additional","affiliation":[{"name":"Oregon Health & Science University , Departments of Obstetrics and Gynecology and Urology , Portland , OR , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron B.","family":"Caughey","sequence":"additional","affiliation":[{"name":"Oregon Health & Science University , Departments of Obstetrics and Gynecology and Urology , Portland , OR , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2020,8,18]]},"reference":[{"key":"2023033121512593677_j_jpm-2020-0199_ref_001","doi-asserted-by":"crossref","unstructured":"Butler, EL, Cox, SM, Eberts, EG, Cunningham, FG. 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