{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T08:59:49Z","timestamp":1791622789258,"version":"4.3.4"},"reference-count":51,"publisher":"Walter de Gruyter GmbH","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,2,23]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_jpm-2020-0289_abs_001_w2aab3b7c68b1b6b1aab1c16b1Aa\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Preterm labour is the leading cause of hospitalization during pregnancy. In France, it results in more than 60,000 births before 37\u00a0weeks of gestation every year. Recent studies suggest that detection of placental \u03b1-microglobulin-1 (PAMG-1) in vaginal secretions among women presenting symptoms of preterm labour with intact membranes has good predictive value for the onset of spontaneous preterm delivery within 7 days. The test is especially interesting, in that the repetition of antenatal corticosteroids for foetal lung maturation is no longer recommended in France and the effect of the initial administration is most beneficial in the 24\u00a0h to 7 days afterwards.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jpm-2020-0289_abs_002_w2aab3b7c68b1b6b1aab1c16b2Aa\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We included all studies listed in PubMed and\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/clinicaltrials.gov\">clinicaltrials.gov<\/jats:ext-link>\n                      with the terms \u201cPAMG-1\u201d and either \u201cpreterm labor\u201d or \u201cpreterm labour\u201d, while excluding all studies on the subject of \u201crupture of the membranes\u201d from 2000 through 2017. Ten studies were thus included.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jpm-2020-0289_abs_003_w2aab3b7c68b1b6b1aab1c16b3Aa\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In women who had both the PAMG-1 and foetal fibronectin test, the PAMG-1 test was statistically superior to the measurement of cervical length for positive predictive value (p&lt;0.0074), negative predictive value (p=0.0169) and specificity (p&lt;0.001) for the prediction of spontaneous preterm delivery within 7 days.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jpm-2020-0289_abs_004_w2aab3b7c68b1b6b1aab1c16b4Aa\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The use of PAMG-1 may make it possible to target the women at risk with a shortened cervix on ultrasound (&lt;25\u00a0mm) those with an imminent preterm delivery and therefore to adapt management, especially the administration of antenatal corticosteroid therapy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1515\/jpm-2020-0289","type":"journal-article","created":{"date-parts":[[2020,10,5]],"date-time":"2020-10-05T02:36:23Z","timestamp":1601865383000},"page":"119-126","source":"Crossref","is-referenced-by-count":8,"title":["Methods of detection and prevention of preterm labour and the PAMG-1 detection test: a review"],"prefix":"10.1515","volume":"49","author":[{"given":"Vincent","family":"Dochez","sequence":"first","affiliation":[{"name":"Service de Gyn\u00e9cologie-Obst\u00e9trique , CHU de Nantes , Nantes , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillaume","family":"Ducarme","sequence":"additional","affiliation":[{"name":"Service de Gyn\u00e9cologie-Obst\u00e9trique , CHD Vend\u00e9e , La Roche sur Yon , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pauline","family":"Gueudry","sequence":"additional","affiliation":[{"name":"Service de Gyn\u00e9cologie-Obst\u00e9trique , CHU de Nantes , Nantes , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yolaine","family":"Joueidi","sequence":"additional","affiliation":[{"name":"Service de Gyn\u00e9cologie-Obst\u00e9trique , CHU de Nantes , Nantes , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marion","family":"Boivin","sequence":"additional","affiliation":[{"name":"Centre d\u2019Investigation Clinique CIC FEA , CHU de Nantes , Nantes , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louise","family":"Boussamet","sequence":"additional","affiliation":[{"name":"Centre d\u2019Investigation Clinique CIC FEA , CHU de Nantes , Nantes , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e9l\u00e8ne","family":"Pelerin","sequence":"additional","affiliation":[{"name":"Unit\u00e9 de Recherche Clinique URC , CHD Vend\u00e9e , La Roche sur Yon , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aur\u00e9lie","family":"Le Thuaut","sequence":"additional","affiliation":[{"name":"Plateforme de Statistiques \u2013 Direction de la Recherche , CHU de Nantes , Nantes , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeineb","family":"Lamoureux","sequence":"additional","affiliation":[{"name":"Coordination Cellule Recherche Non Interventionnelle \u2013 Direction de la Recherche , CHU de Nantes , Nantes , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Val\u00e9ry-Pierre","family":"Riche","sequence":"additional","affiliation":[{"name":"Cellule Innovation \u2013 D\u00e9partement Partenariat et Innovation \u2013 Direction de la Recherche , CHU de Nantes , Nantes , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norbert","family":"Winer","sequence":"additional","affiliation":[{"name":"Service de Gyn\u00e9cologie-Obst\u00e9trique , CHU de Nantes , Nantes , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thibault","family":"Thubert","sequence":"additional","affiliation":[{"name":"Service de Gyn\u00e9cologie-Obst\u00e9trique , CHU de Nantes , Nantes , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilie","family":"Marie","sequence":"additional","affiliation":[{"name":"Service de Gyn\u00e9cologie-Obst\u00e9trique , CHU de Nantes , Nantes , France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2020,10,2]]},"reference":[{"key":"2023040100154850086_j_jpm-2020-0289_ref_001_w2aab3b7c68b1b6b1ab2b1b1Aa","doi-asserted-by":"crossref","unstructured":"Sentilhes, L, S\u00e9nat, M-V, Ancel, P-Y, Azria, E, Benoist, G, Blanc, J, et al. Prevention of spontaneous preterm birth: guidelines for clinical practice from the French College of Gynaecologists and Obstetricians (CNGOF). Eur J Obstet Gynecol Reprod Biol 2016;210:217\u201324. https:\/\/doi.org\/10.1016\/j.ejogrb.2016.12.035.","DOI":"10.1016\/j.ejogrb.2016.12.035"},{"key":"2023040100154850086_j_jpm-2020-0289_ref_002_w2aab3b7c68b1b6b1ab2b1b2Aa","unstructured":"Haute Autorit\u00e9 de Sant\u00e9. Mesure de la longueur du canal cervical du col de l\u2019ut\u00e9rus par \u00e9chographie par voie vaginale\u202f: int\u00e9r\u00eat dans la pr\u00e9vision de l\u2019accouchement pr\u00e9matur\u00e9 spontan\u00e9. Rapport d\u2019\u00e9valuation technologique ; 2010. Available from: http:\/\/www.has-sante.fr\/portail\/jcms\/c_894981\/fr\/mesure-de-la-longueur-du-canal-cervical-du-col-de-l-uterus-par-echographie-par-voie-vaginale-interet-dans-la-prevision-de-l-accouchement-premature-spontane [Accessed 22 Jan 2017]."},{"key":"2023040100154850086_j_jpm-2020-0289_ref_003_w2aab3b7c68b1b6b1ab2b1b3Aa","doi-asserted-by":"crossref","unstructured":"Hueston, W. Preterm contractions in community settings: II. Predicting preterm birth in women with preterm contractions. Obstet Gynecol 1998;92:43\u20136. https:\/\/doi.org\/10.1016\/S0029-7844(98)00108-2.","DOI":"10.1016\/S0029-7844(98)00108-2"},{"key":"2023040100154850086_j_jpm-2020-0289_ref_004_w2aab3b7c68b1b6b1ab2b1b4Aa","unstructured":"Cabrol, D, Goffinet, F, Carbonne, B, Dreyfus, M, Ercole, C, Ancel, P-Y. La menace d\u2018accouchement pr\u00e9matur\u00e9 (MAP) \u00e0 membranes intactes. Recommandations du CNGOF; 2002. Available from: http:\/\/www.cngof.net\/Journees-CNGOF\/MAJ-GO\/RPC\/MAP-2002.pdf [Accessed 27 Sep 2020]."},{"key":"2023040100154850086_j_jpm-2020-0289_ref_005_w2aab3b7c68b1b6b1ab2b1b5Aa","unstructured":"Ancel, P-Y. Menace d\u2019accouchement pr\u00e9matur\u00e9 et travail pr\u00e9matur\u00e9 \u00e0 membranes intactes\u202fntphysiopathologie, facteurs de risque et consequences ; 2008. Available from: http:\/\/www.em-consulte.com\/en\/article\/114614#JGYN-11-2002-31-S7-0368-2315-101019-ART3-BIB10 [Accessed 5 Mar 2017]."},{"key":"2023040100154850086_j_jpm-2020-0289_ref_006_w2aab3b7c68b1b6b1ab2b1b6Aa","unstructured":"American College of Obstetricians and Gynecologists. ACOG Practice Bulletin. Assessment of risk factors for preterm birth. Clinical management guidelines for obstetrician-gynecologists. Number 31, October 2001. 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