{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T03:31:40Z","timestamp":1786505500473,"version":"build-2736575974"},"reference-count":32,"publisher":"Walter de Gruyter GmbH","issue":"4","funder":[{"name":"The Finnish Medical Foundation","award":["3611"],"award-info":[{"award-number":["3611"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,5,26]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_jpm-2020-0379_abs_001_w2aab3b7c39b1b6b1aab1c15b1Aa\">\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>Gestational IDA has been linked to adverse maternal and neonatal outcomes, but the impact of iron supplementation on outcome measures remains unclear. Our objective was to assess the effects of gestational IDA on pregnancy outcomes and compare outcomes in pregnancies treated with either oral or intravenous iron supplementation.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2020-0379_abs_002_w2aab3b7c39b1b6b1aab1c15b2Aa\">\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We evaluated maternal and neonatal outcomes in 215 pregnancies complicated with gestational IDA (Hb&lt;100\u00a0g\/L) and delivered in our tertiary unit between January 2016 and October 2018. All pregnancies from the same period served as a reference group (n=11,545). 163 anemic mothers received oral iron supplementation, and 52 mothers received intravenous iron supplementation.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2020-0379_abs_003_w2aab3b7c39b1b6b1aab1c15b3Aa\">\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Gestational IDA was associated with an increased risk of preterm birth (10.2% vs. 6.1%, p=0.009) and fetal growth restriction (FGR) (1.9% vs. 0.3%, p=0.006). The gestational IDA group that received intravenous iron supplementation had a greater increase in Hb levels compared to those who received oral medication (18.0\u00a0g\/L vs. 10.0\u00a0g\/L, p&lt;0.001), but no statistically significant differences in maternal and neonatal outcomes were detected.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2020-0379_abs_004_w2aab3b7c39b1b6b1aab1c15b4Aa\">\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Compared to the reference group, prematurity, FGR, postpartum infections, and extended hospital stays were more common among mothers with gestational IDA, causing an additional burden on the families and the healthcare system.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/jpm-2020-0379","type":"journal-article","created":{"date-parts":[[2020,12,22]],"date-time":"2020-12-22T10:48:12Z","timestamp":1608634092000},"page":"431-438","source":"Crossref","is-referenced-by-count":49,"title":["Gestational iron deficiency anemia is associated with preterm birth, fetal growth restriction, and postpartum infections"],"prefix":"10.1515","volume":"49","author":[{"given":"Lotta","family":"Kemppinen","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology , Turku University Hospital , Turku , Finland"},{"name":"University of Turku , Turku , Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirjami","family":"Mattila","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Turku University Hospital , Turku , Finland"},{"name":"University of Turku , Turku , Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eeva","family":"Ekholm","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Turku University Hospital , Turku , Finland"},{"name":"University of Turku , Turku , Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nanneli","family":"Pallasmaa","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Turku University Hospital , Turku , Finland"},{"name":"University of Turku , Turku , Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ari","family":"T\u00f6rm\u00e4","sequence":"additional","affiliation":[{"name":"University of Turku , Turku , Finland"},{"name":"Department of Clinical Laboratory , Turku University Hospital , Turku , Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leila","family":"Varakas","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Turku University Hospital , Turku , Finland"},{"name":"University of Turku , Turku , Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaarin","family":"M\u00e4kikallio","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Turku University Hospital , Turku , Finland"},{"name":"University of Turku , Turku , Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2020,12,21]]},"reference":[{"key":"2023040100375560703_j_jpm-2020-0379_ref_001_w2aab3b7c39b1b6b1ab2b2b1Aa","doi-asserted-by":"crossref","unstructured":"Daru, J, Sobhy, S, Pavord, S. 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