{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T21:38:41Z","timestamp":1761514721924},"reference-count":32,"publisher":"Walter de Gruyter GmbH","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,6,25]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_jpm-2020-0386_abs_001_w2aab3b7c18b1b6b1aab1c16b1Aa\">\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>We aim to study the association of maternal age with maternal and neonatal complications in twin pregnancies.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2020-0386_abs_002_w2aab3b7c18b1b6b1aab1c16b2Aa\">\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A retrospective cohort study of dichorionic\u2013diamniotic twin pregnancies stratified into three groups according to maternal age (\u201cA\u201d &lt;25, \u201cB\u201d 25\u201334 and \u201cC\u201d 35\u201344 years old). Outcome measures included pregnancy, delivery and neonatal complications. A sub-analysis of <jats:italic>in vitro<\/jats:italic> fertilization pregnancies only was conducted.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2020-0386_abs_003_w2aab3b7c18b1b6b1aab1c16b3Aa\">\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Compared with younger women (groups A [n=65] and B [n=783]), older women [group C (n=392)] demonstrated significantly higher rates of gestational diabetes mellitus (B 6.6% vs. A 0%, p =0.027, C 10.2% vs. B 6.6%, p =0.032), were more likely to undergo cesarean deliveries (C 66.6%, B 57.6%, A 52.3%, p =0.007), and were at increased risk of having more than 20% difference in weight between the twins (C 24.5%, B 17.4%, A 16.9%, p =0.013). Other outcomes, including preeclampsia, did not differ between the groups. A sub-analysis of the <jats:italic>in vitro<\/jats:italic> fertilization only pregnancies was performed. Compared with younger women (groups A [n=18] and B [n=388]), older women (group C [n=230]) underwent more cesarean deliveries (p=0.004), and had more than 20% difference in weight between the twins (p&lt;0.004). Other outcomes, including gestational diabetes mellitus rates and preeclampsia, did not differ between the groups.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2020-0386_abs_004_w2aab3b7c18b1b6b1aab1c16b4Aa\">\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Women at advanced maternal age with dichorionic twin pregnancies had significantly higher rates of gestational diabetes mellitus, cesarean deliveries and fetal weight discordancy as compared with younger women. In contrast, the incidence of preeclampsia was not affected by maternal age.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/jpm-2020-0386","type":"journal-article","created":{"date-parts":[[2021,2,19]],"date-time":"2021-02-19T08:51:26Z","timestamp":1613724686000},"page":"559-565","source":"Crossref","is-referenced-by-count":11,"title":["Pregnancy and neonatal outcomes of twin pregnancies\u00a0\u2013 the role of maternal age"],"prefix":"10.1515","volume":"49","author":[{"given":"Shlomi","family":"Toussia-Cohen","sequence":"first","affiliation":[{"name":"The Department of Obstetrics and Gynecology , Chaim Sheba Medical Center , Ramat-Gan , Israel"},{"name":"The Sackler Faculty of Medicine, Tel-Aviv University , Tel-Aviv , Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aya","family":"Mohr-Sasson","sequence":"additional","affiliation":[{"name":"The Department of Obstetrics and Gynecology , Chaim Sheba Medical Center , Ramat-Gan , Israel"},{"name":"The Sackler Faculty of Medicine, Tel-Aviv University , Tel-Aviv , Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abraham","family":"Tsur","sequence":"additional","affiliation":[{"name":"The Department of Obstetrics and Gynecology , Chaim Sheba Medical Center , Ramat-Gan , Israel"},{"name":"The Sackler Faculty of Medicine, Tel-Aviv University , Tel-Aviv , Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriel","family":"Levin","sequence":"additional","affiliation":[{"name":"The Department of Obstetrics and Gynecology , Hadassah-Hebrew University Medical Center , Jerusalem , Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raoul","family":"Orvieto","sequence":"additional","affiliation":[{"name":"The Department of Obstetrics and Gynecology , Chaim Sheba Medical Center , Ramat-Gan , Israel"},{"name":"The Sackler Faculty of Medicine, Tel-Aviv University , Tel-Aviv , Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronit","family":"Machtinger","sequence":"additional","affiliation":[{"name":"The Department of Obstetrics and Gynecology , Chaim Sheba Medical Center , Ramat-Gan , Israel"},{"name":"The Sackler Faculty of Medicine, Tel-Aviv University , Tel-Aviv , Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raanan","family":"Meyer","sequence":"additional","affiliation":[{"name":"The Department of Obstetrics and Gynecology , Chaim Sheba Medical Center , Ramat-Gan , Israel"},{"name":"The Sackler Faculty of Medicine, Tel-Aviv University , Tel-Aviv , Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2021,2,18]]},"reference":[{"key":"2023033123480311088_j_jpm-2020-0386_ref_001_w2aab3b7c18b1b6b1ab2b1b1Aa","doi-asserted-by":"crossref","unstructured":"Osterman, MJ, Kochanek, KD, MacDorman, MF, Strobino, DM, Guyer, B. 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