{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T19:37:22Z","timestamp":1793907442031,"version":"4.8.0"},"reference-count":48,"publisher":"Walter de Gruyter GmbH","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,6,25]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_jpm-2020-0543_abs_001_w2aab3b7c53b1b6b1aab1c16b1Aa\">\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Neonatal lupus erythematosus is an autoimmune disease acquired during fetal life as a result of transplacental passage of maternal anti-Sj\u00f6gren\u2019s-syndrome-related antigen A (anti-SSA\/Ro), anti-Sj\u00f6gren\u2019s-syndrome-related antigen B (anti-SSB\/La) or anti-U1 ribonucleoprotein (anti-U1-RNP) antinuclear autoantibodies.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2020-0543_abs_002_w2aab3b7c53b1b6b1aab1c16b2Aa\">\n                  <jats:title>Contents<\/jats:title>\n                  <jats:p>Clinical manifestations include skin lesions, congenital heart block, hepatobiliary involvement and cytopenias. Most of the disorders disappear spontaneously after clearance of maternal antibodies. Cardiac symptoms, however, are not self-resolving and often pacemaker implantation is required. Diagnosis is based on clinical presentation and the presence of typical antibodies in the mother\u2019s or infant\u2019s serum.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2020-0543_abs_003_w2aab3b7c53b1b6b1aab1c16b3Aa\">\n                  <jats:title>Outlook<\/jats:title>\n                  <jats:p>Neonatal lupus erythematosus may develop in children born to anti-SSA\/Ro or anti-SSB\/La women with various systemic connective tissue diseases. However, in half of the cases, the mother is asymptomatic, which may delay the diagnosis and have negative impact on the child\u2019s prognosis. Testing for antinuclear antibodies should be considered in every pregnant woman since early treatment with hydroxychloroquine or intravenous immunoglobulin (IVIG) has proven to be effective in preventing congenital heart block.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/jpm-2020-0543","type":"journal-article","created":{"date-parts":[[2021,1,23]],"date-time":"2021-01-23T04:44:19Z","timestamp":1611377059000},"page":"529-538","source":"Crossref","is-referenced-by-count":53,"title":["Neonatal lupus erythematosus\u00a0\u2013 practical guidelines"],"prefix":"10.1515","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9624-1540","authenticated-orcid":false,"given":"Julia Marta","family":"Derdulska","sequence":"first","affiliation":[{"name":"Department of Dermatology , Medical University of Warsaw , Warsaw , Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8308-1023","authenticated-orcid":false,"given":"Lidia","family":"Rudnicka","sequence":"additional","affiliation":[{"name":"Department of Dermatology , Medical University of Warsaw , Warsaw , Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6158-8993","authenticated-orcid":false,"given":"Agata","family":"Szykut-Badaczewska","sequence":"additional","affiliation":[{"name":"Department of Dermatology , Medical University of Warsaw , Warsaw , Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6411-9172","authenticated-orcid":false,"given":"Dorota","family":"Mehrholz","sequence":"additional","affiliation":[{"name":"Department of Dermatology , Medical University of Gda\u0144sk , Gda\u0144sk , Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4768-1387","authenticated-orcid":false,"given":"Roman J.","family":"Nowicki","sequence":"additional","affiliation":[{"name":"Department of Dermatology , Medical University of Gda\u0144sk , Gda\u0144sk , Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4018-6706","authenticated-orcid":false,"given":"Wioletta","family":"Bara\u0144ska-Rybak","sequence":"additional","affiliation":[{"name":"Department of Dermatology , Medical University of Gda\u0144sk , Gda\u0144sk , Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6316-983X","authenticated-orcid":false,"given":"Aleksandra","family":"Wilkowska","sequence":"additional","affiliation":[{"name":"Department of Dermatology , Medical University of Gda\u0144sk , Gda\u0144sk , Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2021,1,18]]},"reference":[{"key":"2023033123480317713_j_jpm-2020-0543_ref_001_w2aab3b7c53b1b6b1ab2b1b1Aa","doi-asserted-by":"crossref","unstructured":"Vanoni, F, Lava, SA, Fossali, EF, Cavalli, R, Simonetti, GD, Bianchetti, MG, et al.. 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Ann Rheum Dis 2016;75:1161\u20135. https:\/\/doi.org\/10.1136\/annrheumdis-2015-208311.","DOI":"10.1136\/annrheumdis-2015-208311"},{"key":"2023033123480317713_j_jpm-2020-0543_ref_042_w2aab3b7c53b1b6b1ab2b1c42Aa","doi-asserted-by":"crossref","unstructured":"Brito-Zer\u00f3n, P, Izmirly, PM, Ramos-Casals, M, Buyon, JP, Khamashta, MA. The clinical spectrum of autoimmune congenital heart block. Nat Rev Rheumatol 2015;11:301. https:\/\/doi.org\/10.1038\/nrrheum.2015.29.","DOI":"10.1038\/nrrheum.2015.29"},{"key":"2023033123480317713_j_jpm-2020-0543_ref_043_w2aab3b7c53b1b6b1ab2b1c43Aa","doi-asserted-by":"crossref","unstructured":"Izmirly, PM, Costedoat-Chalumeau, N, Pisoni, CN, Khamashta, MA, Kim, MY, Saxena, A, et al.. Maternal use of hydroxychloroquine is associated with a reduced risk of recurrent anti-SSA\/Ro-antibody\u2013associated cardiac manifestations of neonatal lupus. Circulation 2012;126:76\u201382. https:\/\/doi.org\/10.1161\/circulationaha.111.089268.","DOI":"10.1161\/CIRCULATIONAHA.111.089268"},{"key":"2023033123480317713_j_jpm-2020-0543_ref_044_w2aab3b7c53b1b6b1ab2b1c44Aa","doi-asserted-by":"crossref","unstructured":"Barsalou, J, Jaeggi, E, Laskin, CA, Brown, P, Tian, SY, Hamilton, RM, et al.. Prenatal exposure to antimalarials decreases the risk of cardiac but not non-cardiac neonatal lupus: a single-centre cohort study. Rheumatology 2017;56:1552\u20139. https:\/\/doi.org\/10.1093\/rheumatology\/kex191.","DOI":"10.1093\/rheumatology\/kex191"},{"key":"2023033123480317713_j_jpm-2020-0543_ref_045_w2aab3b7c53b1b6b1ab2b1c45Aa","doi-asserted-by":"crossref","unstructured":"Yu, Y, Du, L, Pan, J, Zheng, J, Chen, A, Chen, L. A 10-year retrospective study of neonatal lupus erythematous in China. Asian Pac J Allergy 2016;34.","DOI":"10.12932\/AP0671.34.2.2016"},{"key":"2023033123480317713_j_jpm-2020-0543_ref_046_w2aab3b7c53b1b6b1ab2b1c46Aa","doi-asserted-by":"crossref","unstructured":"Izmirly, PM, Saxena, A, Kim, MY, Wang, D, Sahl, SK, Llanos, C, et al.. Maternal and fetal factors associated with mortality and morbidity in a multi-racial\/ethnic registry of anti-SSA\/Ro\u2013associated cardiac neonatal lupus. Circulation 2011;124:1927\u201335. https:\/\/doi.org\/10.1161\/circulationaha.111.033894.","DOI":"10.1161\/CIRCULATIONAHA.111.033894"},{"key":"2023033123480317713_j_jpm-2020-0543_ref_047_w2aab3b7c53b1b6b1ab2b1c47Aa","doi-asserted-by":"crossref","unstructured":"Eliasson, H, Sonesson, S-E, Sharland, G, Granath, F, Simpson, JM, Carvalho, JS, et al.. Isolated atrioventricular block in the fetus: a retrospective, multinational, multicenter study of 175 patients. Circulation 2011;124:1919\u201326. https:\/\/doi.org\/10.1161\/circulationaha.111.041970.","DOI":"10.1161\/CIRCULATIONAHA.111.041970"},{"key":"2023033123480317713_j_jpm-2020-0543_ref_048_w2aab3b7c53b1b6b1ab2b1c48Aa","doi-asserted-by":"crossref","unstructured":"Martin, V, Lee, LA, Askanase, AD, Katholi, M, Buyon, JP. Long\u2010term followup of children with neonatal lupus and their unaffected siblings. 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