{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T08:59:50Z","timestamp":1791622790117,"version":"4.3.4"},"reference-count":35,"publisher":"Walter de Gruyter GmbH","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,11,25]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_jpm-2021-0048_abs_001\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To assess the frequency of antenatal corticosteroid (ACS) administration in cases with shortened cervical length by addition of placental alpha-microglobulin-1 (PAMG-1) testing to sonographic examination.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jpm-2021-0048_abs_002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Single centre retrospective cohort study. Rate of ACS administration was compared between cases with cervical length between 15 and 25\u00a0mm and cases with positive PAMG-1 testing and cervical length between 15 and 25\u00a0mm. We evaluated the following outcome parameters: Rate of ACS administration, gestational age at delivery, time to delivery, delivery within seven days, delivery &lt;34 and\u00a0&lt;37\u00a0weeks\u2019 gestation, rate of admission to neonatal intensive care unit (NICU).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jpm-2021-0048_abs_003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In total, 130 cases were included. \u201cPAMG-1 group\u201d consisted of 68 women, 62 cases built the \u201chistorical control group\u201d. ACS administration was performed less frequently in the \u201cPAMG-1 cohort\u201d (18 (26%) vs. 46 (74%); p&lt;0.001). The rate of delivery within seven days did not differ (2 (3%) vs. 4 (6.5%); p=0.4239). The rates of delivery &lt;34\u00a0weeks\u2019 gestation (7 (10%) vs. 9 (15%); p=0.4643) and &lt;37\u00a0weeks\u2019 gestation (19 (28%) vs. 26 (42%); p=0.0939) did not differ. Time to delivery interval was longer in the PAMG-1 group (61.5 vs. 43\u00a0days, p=0.0117). NICU admission occurred more\u00a0often in the \u201chistorical control group\u201d (22 (38%) vs. 28 (60%); p=0.0272).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jpm-2021-0048_abs_004\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Addition of biomarker testing can help to avoid unnecessary ACS administrations in women with shortened cervical length.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1515\/jpm-2021-0048","type":"journal-article","created":{"date-parts":[[2021,7,16]],"date-time":"2021-07-16T18:11:44Z","timestamp":1626459104000},"page":"1135-1140","source":"Crossref","is-referenced-by-count":3,"title":["The use of PAMG-1 testing in patients with preterm labor, intact membranes and a short sonographic cervix reduces the rate of unnecessary antenatal glucocorticoid administration"],"prefix":"10.1515","volume":"49","author":[{"given":"Sven","family":"Kehl","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology , Erlangen University Hospital , Erlangen , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christel","family":"Weiss","sequence":"additional","affiliation":[{"name":"Department of Medical Statistics and Biomathematics , University Medical Center Mannheim, Heidelberg University , Mannheim , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jutta","family":"Pretscher","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Erlangen University Hospital , Erlangen , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Friederike","family":"Baier","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Erlangen University Hospital , Erlangen , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florian","family":"Faschingbauer","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Erlangen University Hospital , Erlangen , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias W.","family":"Beckmann","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Erlangen University Hospital , Erlangen , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1865-5369","authenticated-orcid":false,"given":"Florian M.","family":"Stumpfe","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Erlangen University Hospital , Erlangen , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2021,7,19]]},"reference":[{"key":"2023033122435017612_j_jpm-2021-0048_ref_001","doi-asserted-by":"crossref","unstructured":"Slattery, MM, Morrison, JJ. 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