{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T00:00:45Z","timestamp":1787702445157,"version":"build-2784847793"},"reference-count":17,"publisher":"Walter de Gruyter GmbH","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,1,27]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_jpm-2021-0058_abs_001\">\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>To review experience with fetoscopic laser ablation of placental anastomoses to treat monochorionic diamniotic (MCDA) twin pregnancies complicated by twin-to-twin transfusion syndrome (TTTS) in a single centre over a ten-year period.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2021-0058_abs_002\">\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A retrospective study on 142 MCDA twin pregnancies complicates by TTTS treated with equatorial laser ablation of placental anastomoses (2008\u20132018). Solomon technique was also applied after 2013. Survival rates, neonatal outcome, intraoperative and post-laser complications were recorded, and prognostic factors analysed.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2021-0058_abs_003\">\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A total of 133 cases were included in the final analysis; 41 patients were at stage II (30.8%), 73 were at stage III (62.9%), while only 12 (9%) at stage I and two patients (1.7%) at stage IV. Solomon technique was applied in 39 cases (29.3%). Survival of both twins was 51.1% (68\/133), of a single twin 20.3% (27\/133), and of at least one 71.5% (95\/133), with an overall survival of 61.3% (163\/266). TAPS and recurrent TTTS occurred in 8 (6%) and 15 (11.3%) patients. Survival of both fetuses increased over time (44.6 vs. 57.3%). A posterior placenta (p&lt;0.003) and the use of the Solomon technique (p&lt;0.02) were more frequent in cases with survival of both fetuses, while TTTS recurrence was significantly associated to the loss of one or two fetuses (p&lt;0.01). Such associations were confirmed at logistic regression analysis.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2021-0058_abs_004\">\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Survival of both twins can improve over time and seems to be favourably associated with a placenta in the posterior location and the use of the Solomon technique.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/jpm-2021-0058","type":"journal-article","created":{"date-parts":[[2021,9,15]],"date-time":"2021-09-15T21:59:51Z","timestamp":1631743191000},"page":"34-41","source":"Crossref","is-referenced-by-count":6,"title":["Fetoscopic laser ablation therapy in monochorionic diamniotic twin pregnancies with twin-to-twin transfusion syndrome treated at a single centre over 10 years: a retrospective study"],"prefix":"10.1515","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7368-0823","authenticated-orcid":false,"given":"Anna","family":"Fichera","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology , Spedali Civili , Brescia , Italy"},{"name":"Department of Clinical and Experimental Sciences , University of Brescia , Brescia , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vita Valentina","family":"Azzaretto","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Spedali Civili , Brescia , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0417-1793","authenticated-orcid":false,"given":"Nicola","family":"Fratelli","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Spedali Civili , Brescia , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Mancino","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Spedali Civili , Brescia , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daria","family":"Marella","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Spedali Civili , Brescia , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatrice","family":"Negri","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Spedali Civili , Brescia , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriana","family":"Valcamonico","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Spedali Civili , Brescia , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Zanardini","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Spedali Civili , Brescia , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiziana","family":"Frusca","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Spedali Civili , Brescia , Italy"},{"name":"Department of Obstetrics and Gynecology , University of Parma , Parma , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrico","family":"Sartori","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Spedali Civili , Brescia , Italy"},{"name":"Department of Clinical and Experimental Sciences , University of Brescia , Brescia , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7793-714X","authenticated-orcid":false,"given":"Federico","family":"Prefumo","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Spedali Civili , Brescia , Italy"},{"name":"Department of Clinical and Experimental Sciences , University of Brescia , Brescia , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2021,9,15]]},"reference":[{"key":"2022011210063982020_j_jpm-2021-0058_ref_001","unstructured":"Berghella, V, Kaufmann, M. 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