{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T03:19:11Z","timestamp":1781925551586,"version":"3.54.5"},"reference-count":12,"publisher":"Walter de Gruyter GmbH","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,5,25]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_jpm-2021-0519_abs_001\">\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>\n                     <jats:italic>Chlamydia trachomatis<\/jats:italic> is one of the most common sexually transmitted diseases in the world, but there are limited data on its impact on perinatal outcomes. Our objective was to investigate the association between chlamydia infections and adverse perinatal outcomes.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2021-0519_abs_002\">\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>This is a retrospective analysis of the United States Centers for Disease Control and Prevention natality live birth database for the years 2016\u20132019. The rates of adverse perinatal outcomes were compared between patients with a chlamydia infection during pregnancy and\u00a0patients without such infection, using Pearson\u2019s chi-square test with the Bonferroni adjustment. A multivariate logistic regression was then used to adjust outcomes for potential confounders.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2021-0519_abs_003\">\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Chlamydia infections were associated with small, but statistically significant, increased odds of preterm birth\u00a0(&lt;37\u00a0weeks), early preterm birth (&lt;32\u00a0weeks), low birthweight (&lt;2,500\u00a0g), congenital anomalies, low 5-min Apgar score (&lt;7), neonatal intensive care unit admission, immediate neonatal ventilation, prolonged (&gt;6\u00a0h) neonatal ventilation, and neonatal antibiotic treatment for suspected sepsis.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2021-0519_abs_004\">\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Chlamydia infections during pregnancy are associated with adverse perinatal outcomes. These results call for increased education regarding the potential risks of pregnancies with a chlamydia infection, as well as for increased antenatal surveillance and post-natal pediatric assessment in these pregnancies.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/jpm-2021-0519","type":"journal-article","created":{"date-parts":[[2021,12,23]],"date-time":"2021-12-23T23:50:21Z","timestamp":1640303421000},"page":"407-410","source":"Crossref","is-referenced-by-count":3,"title":["Adverse perinatal outcomes of chlamydia infections: an ongoing challenge"],"prefix":"10.1515","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4716-6705","authenticated-orcid":false,"given":"Yael","family":"Eliner","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology , Lenox Hill Hospital\u00a0\u2013 Zucker School of Medicine at Hofstra\/Northwell , New York , NY , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1966-9578","authenticated-orcid":false,"given":"Moti","family":"Gulersen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , North Shore University Hospital\u00a0\u2013 Zucker School of Medicine at Hofstra\/Northwell , Manhasset , NY , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amos","family":"Grunebaum","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Lenox Hill Hospital\u00a0\u2013 Zucker School of Medicine at Hofstra\/Northwell , New York , NY , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erez","family":"Lenchner","sequence":"additional","affiliation":[{"name":"Biostatistics and Data Management, New York University Rory Meyers College of Nursing , New York , NY , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2372-7862","authenticated-orcid":false,"given":"Liron","family":"Bar-El","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Lenox Hill Hospital\u00a0\u2013 Zucker School of Medicine at Hofstra\/Northwell , New York , NY , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank A.","family":"Chervenak","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Lenox Hill Hospital\u00a0\u2013 Zucker School of Medicine at Hofstra\/Northwell , New York , NY , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eran","family":"Bornstein","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Lenox Hill Hospital\u00a0\u2013 Zucker School of Medicine at Hofstra\/Northwell , New York , NY , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2021,12,24]]},"reference":[{"key":"2023040100043920439_j_jpm-2021-0519_ref_001","doi-asserted-by":"crossref","unstructured":"Rowley, J, Vander Hoorn, S, Korenromp, E, Low, N, Unemo, M, Abu-Raddad, LJ, et al.. 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