{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T04:50:07Z","timestamp":1747198207248,"version":"3.40.5"},"reference-count":35,"publisher":"Walter de Gruyter GmbH","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,10,26]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_jpm-2021-0688_abs_001\">\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>To evaluate neonatal outcomes after the use of\u00a0a cervical pessary in Japanese women with short cervical length (CL) less than 25\u00a0mm.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2021-0688_abs_002\">\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>This multicenter study involved women with singleton pregnancies between 20 and 29+6 gestational weeks and a CL of less than 25\u00a0mm. The primary outcome was preterm birth (PTB) before 34\u00a0weeks of gestation. This study was registered in the Japan Registry of Clinical Trials (JRCT: jRCTs042180102).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2021-0688_abs_003\">\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Two hundred pregnant women were enrolled; 114 in the pessary group and 86 in the expectant management group as controls. In the pessary group, all 114 neonates were investigated for perinatal outcomes, and 112 pregnant women were investigated for primary, and secondary outcomes. In the control group, 86 pregnant women were investigated for primary and secondary outcomes and 86\u00a0neonates were investigated for neonatal outcomes. There were no significant differences in PTB in\u00a0\u226434,\u00a0\u226437, and\u00a0\u226428\u00a0weeks of gestation or in preterm rupture of membranes (PROM)\u00a0\u226434\u00a0weeks between the groups. The gestational weeks at birth and birth weight were significantly higher in the pessary group. Regression analysis demonstrated that the CL decreased without a pessary, whereas the shortening rate was suppressed during the intervention. No significant differences were observed in adverse neonatal outcomes, chorioamnionitis, or preterm PROM.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2021-0688_abs_004\">\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>The cervical pessary effectively reduced CL\u00a0shortening during pregnancy resulting in an average increased gestational age, however, did not reduced the rates of preterm birth.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/jpm-2021-0688","type":"journal-article","created":{"date-parts":[[2022,5,19]],"date-time":"2022-05-19T20:13:17Z","timestamp":1652991197000},"page":"1107-1114","source":"Crossref","is-referenced-by-count":0,"title":["Does a cervical pessary reduce the rate of preterm birth in women with a short cervix?"],"prefix":"10.1515","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3717-4181","authenticated-orcid":false,"given":"Kyoko","family":"Kumagai","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology , Nagoya City University , Aichi , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Murotsuki","sequence":"additional","affiliation":[{"name":"Department of Maternal and Fetal Medicine , Tohoku University Graduate School of Medicine, Miyagi Children\u2019s Hospital , Miyagi , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Dohi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Showa University Northern Yokohama Hospital , Kanagawa , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naomi","family":"Nishikawa","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Nagoya City University West Medical Center , Aichi , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naomi","family":"Kimura","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Konan Kosei Hospital , Aichi , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makoto","family":"Nomiyama","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , National Hospital Organization Saga Hospital , Saga , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Osaga","sequence":"additional","affiliation":[{"name":"Clinical Research Management Center , Nagoya City University Hospital , Aichi , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1865-4953","authenticated-orcid":false,"given":"Hiroya","family":"Hashimoto","sequence":"additional","affiliation":[{"name":"Clinical Research Management Center , Nagoya City University Hospital , Aichi , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akihito","family":"Nakai","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Tama-Nagayama Hospital, Nippon Medical School , Tokyo , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mayumi","family":"Sugiura-Ogasawara","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Nagoya City University , Aichi , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuhiko","family":"Ozaki","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Nagoya City University Graduate School of Medical Sciences , Aichi , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2022,5,20]]},"reference":[{"key":"2023092212342434178_j_jpm-2021-0688_ref_001","doi-asserted-by":"crossref","unstructured":"Goldenberg, RL, Culhane, JF, Iams, JD, Romero, R. 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