{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T07:16:03Z","timestamp":1750835763233,"version":"3.37.3"},"reference-count":40,"publisher":"Walter de Gruyter GmbH","issue":"2","funder":[{"DOI":"10.13039\/501100005071","name":"Shiraz University","doi-asserted-by":"crossref","award":["Unassigned"],"award-info":[{"award-number":["Unassigned"]}],"id":[{"id":"10.13039\/501100005071","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,2,23]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_jpm-2022-0056_abs_001\">\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>This study aimed to compare pregnant and non-pregnant women infected with SARS-CoV-2 disease (COVID-19) in terms of in-hospital mortality.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2022-0056_abs_002\">\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>This historical cohort study was conducted on hospitalized women of reproductive ages (15\u201349 years) infected with SARS-CoV-2 in Fars province, Iran during 15 March 2019\u201310 May 2021.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2022-0056_abs_003\">\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Out of the 5,322 patients, 330 were pregnant. The fatality rate of SARS-CoV-2 was 1.2% amongst pregnant women and 3.5% amongst non-pregnant ones. Pregnant and non-pregnant women reported the same history of smoking, opium use, previous COVID-19 infection, vaccination against SARS-CoV-2, and COVID-19 symptoms (p&gt;0.05 for all). However, the pregnant women were younger and had fewer underlying diseases (p&lt;0.001 for both). The results revealed no significant difference between the two groups regarding in-hospital clinical manifestations including the number of days after the onset of\u00a0COVID-19 symptoms, mechanical ventilation, and long\u00a0involvement (cRR; 95% CI=0.99 (0.96\u20131.02), 1.18 (0.72\u20132.02), and 0.95 (0.88\u20131.02), respectively). Nonetheless, Intensive Care Unit (ICU) admission was significantly higher in pregnant women (cRR; 95% CI=2.37(1.85\u20133.02)). After adjusting for age, history of underlying diseases, and ICU admission, pregnant women showed lower in-hospital mortality due to COVID-19 compared to non-pregnant women (aRR; 95% CI=0.32 (0.12\u20130.87)).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2022-0056_abs_004\">\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Based on the current study findings, pregnant women showed lower in-hospital mortality due to COVID-19 compared to non-pregnant ones. Nevertheless, they should follow the same recommendations as non-pregnant women, avoiding exposure to the virus and receiving medical treatment and vaccination. Further studies are recommended to address the follow-up of recovered pregnant women, their babies, and puerperium.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/jpm-2022-0056","type":"journal-article","created":{"date-parts":[[2022,3,7]],"date-time":"2022-03-07T13:15:58Z","timestamp":1646658958000},"page":"269-276","source":"Crossref","is-referenced-by-count":1,"title":["Comparison of in-hospital mortality of COVID-19 between pregnant and non-pregnant women infected with SARS-CoV-2: a historical cohort study"],"prefix":"10.1515","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0199-3230","authenticated-orcid":false,"given":"Marjan","family":"Zare","sequence":"first","affiliation":[{"name":"Non-Communicable Diseases Research Center , Shiraz University of Medical Sciences , Shiraz , Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2259-4984","authenticated-orcid":false,"given":"Alireza","family":"Mirahmadizadeh","sequence":"additional","affiliation":[{"name":"Non-Communicable Diseases Research Center , Shiraz University of Medical Sciences , Shiraz , Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7584-2048","authenticated-orcid":false,"given":"Mahsa","family":"Akbari","sequence":"additional","affiliation":[{"name":"Health Affairs , Shiraz University of Medical Sciences , Shiraz , Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2577-4446","authenticated-orcid":false,"given":"Mohammad Javad","family":"Moradian","sequence":"additional","affiliation":[{"name":"Trauma Research Center , Shahid Rajaee (Emtiaz) Trauma Hospital, Shiraz University of Medical Sciences , Shiraz , Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2022,3,7]]},"reference":[{"key":"2023040100500956540_j_jpm-2022-0056_ref_001","doi-asserted-by":"crossref","unstructured":"Carvalho, T, Krammer, F, Iwasaki, A. 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