{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T04:50:09Z","timestamp":1747198209807,"version":"3.40.5"},"reference-count":33,"publisher":"Walter de Gruyter GmbH","issue":"4","funder":[{"name":"The Jack Carey Eichenbaum Research Fund","award":["N\/A"],"award-info":[{"award-number":["N\/A"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,5,25]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_jpm-2022-0113_abs_001\">\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>Antenatal corticosteroids (ACS) administered to mothers at risk for preterm delivery before 34\u00a0weeks has been standard care to improve neonatal outcomes. After introducing a new obstetric policy based on updated recommendations advising the administration of ACS to pregnant women at risk for late preterm (LPT) delivery (34\u201336 6\/7\u00a0weeks), we set out to determine the short-term clinical impact on those LPT neonates.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2022-0113_abs_002\">\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Retrospective chart review of LPT neonates delivered at NYU Langone Medical Center both one\u00a0year before and after the policy went into place. We excluded subjects born to mothers with pre-gestational diabetes, multiple gestations, and those with congenital\/genetic abnormalities. We also excluded subjects whose mothers already received ACS previously in pregnancy. Subjects were divided into pre-policy and post-policy groups. Neonatal and maternal data were compared for both groups.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2022-0113_abs_003\">\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>388 subjects; 180 in the pre-policy and 208 in the post-policy group. This policy change resulted in a significant increase in ACS administration to mothers who delivered LPT neonates (67.3 vs. 20.6%, p&lt;0.001). In turn, there was a significant reduction in LPT neonatal intensive care unit (NICU) admissions (44.2 vs. 54.4%, p=0.04) and need for respiratory support (27.9 vs. 42.8%, p&lt;0.01). However, we also found an increased incidence of hypoglycemia (49.5 vs. 28.3%, p&lt;0.001).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2022-0113_abs_004\">\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>This LPT ACS policy appears effective in reducing the need for LPT NICU level care overall. However, clinicians must be attentive to monitor for adverse effects like hypoglycemia, and there remains a need for better understanding of potential long-term impacts.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/jpm-2022-0113","type":"journal-article","created":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T19:35:25Z","timestamp":1667331325000},"page":"573-579","source":"Crossref","is-referenced-by-count":2,"title":["Impact on neonatal morbidities after a change in policy to administer antenatal corticosteroids to mothers at risk for late preterm delivery"],"prefix":"10.1515","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4743-2452","authenticated-orcid":false,"given":"Pradeep","family":"Mally","sequence":"first","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics , NYU Grossman School of Medicine , New York , NY , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4097-7233","authenticated-orcid":false,"given":"Julia","family":"Katz","sequence":"additional","affiliation":[{"name":"Zucker School of Medicine at Hofstra\/Northwell , Uniondale , NY , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sourabh","family":"Verma","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics , NYU Grossman School of Medicine , New York , NY , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheryl","family":"Purrier","sequence":"additional","affiliation":[{"name":"Division of Neonatal Perinatal Medicine, Department of Pediatrics , Yale School of Medicine , New Haven , CT , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena V.","family":"Wachtel","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics , NYU Grossman School of Medicine , New York , NY , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca","family":"Trillo","sequence":"additional","affiliation":[{"name":"Children\u2019s National Hospital , Washington , DC , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiran","family":"Bhutada","sequence":"additional","affiliation":[{"name":"Albert Einstein College of Medicine , Bronx , NY , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sean M.","family":"Bailey","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics , NYU Grossman School of Medicine , New York , NY , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2022,11,3]]},"reference":[{"key":"2023050402001748619_j_jpm-2022-0113_ref_001","doi-asserted-by":"crossref","unstructured":"Mally, PV, Hendricks-Munoz, KD, Bailey, S. 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