{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T08:12:11Z","timestamp":1787731931810,"version":"build-2784847793"},"reference-count":41,"publisher":"Walter de Gruyter GmbH","issue":"9","license":[{"start":{"date-parts":[[2022,7,8]],"date-time":"2022-07-08T00:00:00Z","timestamp":1657238400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"NIHR Biomedical Research Centre based at Guy\u2019s and St Thomas NHS Foundation Trust and King\u2019s College London","award":["N\/A"],"award-info":[{"award-number":["N\/A"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,11,25]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_jpm-2022-0199_abs_001\">\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>Newborns with congenital diaphragmatic hernia (CDH) can have complex respiratory problems which are worsened by ventilatory induced lung injury. Neurally adjusted ventilator assist (NAVA) is a potentially promising ventilation mode for this population, as it can result in improved patient-ventilator interactions and provision of adequate gas exchange at lower airway pressures.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2022-0199_abs_002\">\n                  <jats:title>Content<\/jats:title>\n                  <jats:p>A literature review was undertaken to provide an overview of NAVA and examine its role in the management of infants with CDH.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2022-0199_abs_003\">\n                  <jats:title>Summary<\/jats:title>\n                  <jats:p>NAVA in neonates has been used in CDH infants who were stable on ventilatory support or being weaned from mechanical ventilation and was associated with a reduction in the level of respiratory support.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2022-0199_abs_004\">\n                  <jats:title>Outlook<\/jats:title>\n                  <jats:p>There is, however, limited evidence regarding the efficacy of NAVA in infants with CDH, with only short-term benefits being investigated. A prospective, multicentre study with long term follow-up is required to appropriately assess NAVA in this population.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/jpm-2022-0199","type":"journal-article","created":{"date-parts":[[2022,7,7]],"date-time":"2022-07-07T07:08:37Z","timestamp":1657177717000},"page":"1163-1167","source":"Crossref","is-referenced-by-count":7,"title":["The use of neurally-adjusted ventilatory assist (NAVA) for infants with congenital diaphragmatic hernia (CDH)"],"prefix":"10.1515","volume":"50","author":[{"given":"Grace","family":"Poole","sequence":"first","affiliation":[{"name":"Department of Child Health , Kings College Hospital NHS Foundation Trust , London , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandeep","family":"Shetty","sequence":"additional","affiliation":[{"name":"Neonatal Unit, St George\u2019s Hospital NHS Foundation Trust , London , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8672-5349","authenticated-orcid":false,"given":"Anne","family":"Greenough","sequence":"additional","affiliation":[{"name":"Department of Women and Children\u2019s Health , School of Life Course Sciences, Faculty of Life Sciences and Medicine, King\u2019s College London , London , UK"},{"name":"National institute for Health Research (NIHR) Biomedical Research Centre at Guy\u2019s and St Thomas\u2019 National Health Service (NHS) Foundation Trust and King\u2019s College London , London , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2022,7,8]]},"reference":[{"key":"2023040100455482061_j_jpm-2022-0199_ref_001","unstructured":"Dumpa, V, Chandrasekharan, P. Congenital diaphragmatic hernia. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022. Available from: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK556076\/ [Accessed 11 Aug 2021]."},{"key":"2023040100455482061_j_jpm-2022-0199_ref_002","unstructured":"Williams, R. Congenital diaphragmatic hernia: a review. Heart Lung 1982;11:532\u201340."},{"key":"2023040100455482061_j_jpm-2022-0199_ref_003","doi-asserted-by":"crossref","unstructured":"Davenport, M, Pierro, A, editors. Neonatal surgery. In: Paediatric Surgery (OSHs in Paediatrics), 1st ed. Oxford, UK: Oxford University Press; 2009:105\u201388 pp.","DOI":"10.1093\/med\/9780199208807.003.0004"},{"key":"2023040100455482061_j_jpm-2022-0199_ref_004","unstructured":"Doherty, H, MacKinnon, RJ. Congenital diaphragmatic hernia -- an update. 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