{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T00:43:33Z","timestamp":1787964213036,"version":"build-2784847793"},"reference-count":45,"publisher":"Walter de Gruyter GmbH","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,9,26]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_jpm-2022-0564_abs_001\">\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>This study aimed to present perinatal outcomes, clinical challenges, and basic ICU management in pregnant women with severe-critical COVID-19 at our tertiary referral center.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2022-0564_abs_002\">\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>In this prospective cohort study, patients were divided into two groups, whether they survived or not. Clinical characteristics, obstetric and neonatal outcomes, initial laboratory test results and radiologic imaging findings, arterial blood gas parameters at ICU admission, and ICU complications and interventions were compared between groups.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2022-0564_abs_003\">\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>157 of the patients survived, and 34 of the patients died. Asthma was the leading health problem among the non-survivors. Fifty-eight patients were intubated, and 24 of them were weaned off and discharged healthfully. Of the\u00a010 patients who underwent ECMO, only 1 survived (p&lt;0.001). Preterm labor was the most common pregnancy complication. Maternal deterioration was the most common indication for a cesarean section. Higher neutrophil-to-lymphocyte-ratio (NLR) values, the need for prone positioning, and the occurrence of an ICU complication were important parameters that influenced maternal mortality (p&lt;0.05).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2022-0564_abs_004\">\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Overweight pregnant women and pregnant women with comorbidities, especially asthma, may have a higher risk of mortality related to COVID-19. A worsening maternal health condition can lead to increased rates of cesarean delivery and iatrogenic prematurity.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/jpm-2022-0564","type":"journal-article","created":{"date-parts":[[2023,5,3]],"date-time":"2023-05-03T19:50:39Z","timestamp":1683143439000},"page":"874-885","source":"Crossref","is-referenced-by-count":7,"title":["Adverse outcomes and maternal complications in pregnant women with severe-critical COVID-19: a\u00a0tertiary center experience"],"prefix":"10.1515","volume":"51","author":[{"given":"Selcan","family":"Sinaci","sequence":"first","affiliation":[{"name":"Clinic of Perinatology, Department of Obstetrics and Gynaecology , Ministry of Health, Ankara City Hospital , Ankara , T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atakan","family":"Tanacan","sequence":"additional","affiliation":[{"name":"Clinic of Perinatology, Department of Obstetrics and Gynaecology , Ministry of Health, Ankara 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