{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,12,21]],"date-time":"2023-12-21T00:14:39Z","timestamp":1703117679294},"reference-count":12,"publisher":"Walter de Gruyter GmbH","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,11,27]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_jpm-2023-0053_abs_001\">\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>To describe embryonic and fetal tiny pericardial fluid collections (PFCs) using transvaginal sonography and HDlive Silhouette at less than 12 weeks of gestation.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2023-0053_abs_002\">\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>During an 8-month period from November 2021 to June 2022, one-hundred and thirty transvaginal scans were performed for first-trimester dating, and eleven tiny PFCs of the embryo or fetus were identified at 8+4 \u2013 11+3 weeks of gestation (three at 8, six at 9, and two at 11 weeks). HDlive Silhouette features of PFC were evaluated. Their clinical characteristics and outcomes were also investigated.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2023-0053_abs_003\">\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The incidence of tiny PFCs was 8.5\u202f% at less than 12 weeks of gestation. The mean gestational age at the initial examination was 9.5 weeks (SD: \u00b1 0.9). The mean crown-rump length was 25.0\u202fmm (SD: \u00b1 8.5). The mean PFC dimension was 0.8\u202fmm (range: 0.5\u20131.3, SD: \u00b1 0.2). Pleural effusion was associated with 3 out of 11 PFCs (27.2\u202f%). Ascites was noted in 2 cases (18.2\u202f%). Skin edema was identified in only in 1 case (0.09\u202f%). There was no arrhythmia. Tiny PFC could also be depicted using HDlive Silhouette. First-trimester fetal ultrasound scans at 11 \u2013 13+6 weeks showed no abnormal findings. PFCs resolved until 13 weeks of gestation (Mean: 12 weeks, SD: \u00b1 1.2). All PFC pregnancies resulted in healthy neonates.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2023-0053_abs_004\">\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>The incidence of tiny PFCs was relatively high in early pregnancy. HDlive Silhouette can depict tiny PFCs of the embryo. Tiny PFCs in early gestation are transient, benign findings <jats:italic>in utero<\/jats:italic>.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/jpm-2023-0053","type":"journal-article","created":{"date-parts":[[2023,7,13]],"date-time":"2023-07-13T15:19:47Z","timestamp":1689261587000},"page":"1206-1211","source":"Crossref","is-referenced-by-count":0,"title":["Embryonic and fetal tiny pericardial fluid collections at less than 12 weeks of gestation"],"prefix":"10.1515","volume":"51","author":[{"given":"Toshiyuki","family":"Hata","sequence":"first","affiliation":[{"name":"Department of Perinatology and Gynecology , Kagawa University School of Medicine , Miki , Kagawa , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomomi","family":"Kawahara","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Miyake Clinic , Okayama , Okayama , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takahito","family":"Miyake","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Miyake Clinic , Okayama , Okayama , Japan"},{"name":"Department of Perinatology and Gynecology , Kagawa University Graduate School of Medicine , Kagawa , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2023,7,13]]},"reference":[{"key":"2023122016104804119_j_jpm-2023-0053_ref_001","doi-asserted-by":"crossref","unstructured":"Hata, T, Fujiwaki, R, Senoh, D, Hata, K. Intrauterine sonographic assessments of embryonal liver length. Hum Reprod 1996;11:1758\u20132761. https:\/\/doi.org\/10.1093\/oxfordjournals.humrep.a019204.","DOI":"10.1093\/oxfordjournals.humrep.a019204"},{"key":"2023122016104804119_j_jpm-2023-0053_ref_002","doi-asserted-by":"crossref","unstructured":"Medina, O, Gomez, J, Mejia, C, Ramirez, J. First-trimester diagnosis of pleural effusion. Ultrasound Obstet Gynecol 2002;19:423\u20134. https:\/\/doi.org\/10.1046\/j.1469-0705.2002.00674.x.","DOI":"10.1046\/j.1469-0705.2002.00674.x"},{"key":"2023122016104804119_j_jpm-2023-0053_ref_003","doi-asserted-by":"crossref","unstructured":"Hashimoto, K, Shimizu, T, Fukuda, M, Ozaki, M, Shimoya, K, Koyama, M, et al.. Pregnancy outcome of embryonic\/fetal pleural effusion in the first trimester. 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