{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T14:00:13Z","timestamp":1782396013377,"version":"3.54.5"},"reference-count":33,"publisher":"Walter de Gruyter GmbH","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,10,26]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_jpm-2023-0078_abs_001\">\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>To compare outcomes of monochorionic diamniotic (MCDA) twin pregnancies by <jats:italic>in\u00a0vitro<\/jats:italic> fertilization (IVF) vs. spontaneously conceived counterparts.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2023-0078_abs_002\">\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Retrospective comparison. Data about MCDA twin pregnancies, conceived spontaneously or by IVF, attending the Twin Pregnancy Care Unit of Sant\u2019Anna Hospital in Turin (Italy) between January 1st 2010 and March 31st 2022, were collected retrospectively. Obstetric, fetal, and neonatal outcomes of MCDA twin pregnancies by IVF were compared to those of spontaneously conceived counterparts. Data were described by univariate and multivariate analysis.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2023-0078_abs_003\">\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>541 MCDA twin pregnancies were included in the study, among which 45 conceived by IVF and 496 spontaneously conceived. Women with IVF twins were older than those who conceived spontaneously (36.7\u00a0\u00b1\u00a05.7 vs. 32.1\u00a0\u00b1\u00a05.2 years; p&lt;0.001). No significant difference in the prevalence of\u00a0pregnancy complications between the two groups was found, except for an increased incidence of hypertensive disorders among IVF pregnancies (17.8 vs. 8.5\u202f%; p=0.039), which resulted nonsignificant after adjusting for maternal age and parity (aOR 1.9, 95\u202f% CI 0.8\u20134.6). Data about 1,046 live born babies (90 conceived by IVF and 956 spontaneously) were also collected: perinatal outcomes did not differ between the two groups.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2023-0078_abs_004\">\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Our results suggest that MCDA twin pregnancies following IVF are not at increased risk of adverse outcomes compared to spontaneous MCDA twin pregnancies.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/jpm-2023-0078","type":"journal-article","created":{"date-parts":[[2023,7,25]],"date-time":"2023-07-25T12:50:27Z","timestamp":1690289427000},"page":"1019-1024","source":"Crossref","is-referenced-by-count":2,"title":["Retrospective comparison of monochorionic diamniotic twin pregnancies stratified by spontaneous or artificial conception"],"prefix":"10.1515","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1540-4927","authenticated-orcid":false,"given":"Sofia","family":"Roero","sequence":"first","affiliation":[{"name":"Twin Pregnancy Care Unit, Gynecology and Obstetrics 2U , A.O.U. Citt\u00e0 della Salute e della Scienza, Sant\u2019Anna Obstetric Gynecological Hospital, University of Torino , Torino , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvana","family":"Arduino","sequence":"additional","affiliation":[{"name":"Twin Pregnancy Care Unit, Gynecology and Obstetrics 2U , A.O.U. Citt\u00e0 della Salute e della Scienza, Sant\u2019Anna Obstetric Gynecological Hospital, University of Torino , Torino , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arianna","family":"Arese","sequence":"additional","affiliation":[{"name":"Twin Pregnancy Care Unit, Gynecology and Obstetrics 2U , A.O.U. Citt\u00e0 della Salute e della Scienza, Sant\u2019Anna Obstetric Gynecological Hospital, University of Torino , Torino , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa","family":"Fea","sequence":"additional","affiliation":[{"name":"Twin Pregnancy Care Unit, Gynecology and Obstetrics 2U , A.O.U. Citt\u00e0 della Salute e della Scienza, Sant\u2019Anna Obstetric Gynecological Hospital, University of Torino , Torino , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabella","family":"Ferrando","sequence":"additional","affiliation":[{"name":"Twin Pregnancy Care Unit, Gynecology and Obstetrics 2U , A.O.U. Citt\u00e0 della Salute e della Scienza, Sant\u2019Anna Obstetric Gynecological Hospital, University of Torino , Torino , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriella","family":"Scaltrito","sequence":"additional","affiliation":[{"name":"Twin Pregnancy Care Unit, Gynecology and Obstetrics 2U , A.O.U. Citt\u00e0 della Salute e della Scienza, Sant\u2019Anna Obstetric Gynecological Hospital, University of Torino , Torino , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viola","family":"Casula","sequence":"additional","affiliation":[{"name":"Twin Pregnancy Care Unit, Gynecology and Obstetrics 2U , A.O.U. Citt\u00e0 della Salute e della Scienza, Sant\u2019Anna Obstetric Gynecological Hospital, University of Torino , Torino , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alice","family":"Ronco","sequence":"additional","affiliation":[{"name":"Twin Pregnancy Care Unit, Gynecology and Obstetrics 2U , A.O.U. Citt\u00e0 della Salute e della Scienza, Sant\u2019Anna Obstetric Gynecological Hospital, University of Torino , Torino , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlotta","family":"Bossotti","sequence":"additional","affiliation":[{"name":"Twin Pregnancy Care Unit, Gynecology and Obstetrics 2U , A.O.U. Citt\u00e0 della Salute e della Scienza, Sant\u2019Anna Obstetric Gynecological Hospital, University of Torino , Torino , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Zizzo","sequence":"additional","affiliation":[{"name":"Twin Pregnancy Care Unit, Gynecology and Obstetrics 2U , A.O.U. Citt\u00e0 della Salute e della Scienza, Sant\u2019Anna Obstetric Gynecological Hospital, University of Torino , Torino , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Scali","sequence":"additional","affiliation":[{"name":"Twin Pregnancy Care Unit, Gynecology and Obstetrics 2U , A.O.U. Citt\u00e0 della Salute e della Scienza, Sant\u2019Anna Obstetric Gynecological Hospital, University of Torino , Torino , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Revelli","sequence":"additional","affiliation":[{"name":"Twin Pregnancy Care Unit, Gynecology and Obstetrics 2U , A.O.U. 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