{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T11:30:02Z","timestamp":1772623802424,"version":"3.50.1"},"reference-count":34,"publisher":"Walter de Gruyter GmbH","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,6,25]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_jpm-2023-0351_abs_001\">\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>The purpose of this study was to explore whether fibrinogen (Fib) can be used as a predictor of postpartum hemorrhage (PPH) in parturients with vaginal delivery, and the value of combining Fib with other indexes to predict postpartum hemorrhage in vaginal delivery.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2023-0351_abs_002\">\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A total of 207 parturients who delivered via vagina were divided into PPH group (n=102) and non-PPH group (n=105). The PPH group was further divided into mild\u00a0PPH group and severe PPH group. The differences of Fib, platelet (PLT), mean platelet volume (MPV), platelet distribution width (PDW), D-dimer (D-D), hemoglobin (HGB) and neonatal weight (Nw) between the two groups were compared to explore the significance of these indexes in predicting PPH.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2023-0351_abs_003\">\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Fib, PLT and PDW in PPH group were significantly lower than those in non-PPH group, while D-D and Nw in PPH group were significantly higher than those in non-PPH group. In the binary logistic regression model, we found that Fib, D-D and Nw were independently related to PPH. The risk of PPH increased by 9.87 times for every 1\u202fg\/L decrease in Fib. The cut-off value of Fib is 4.395 (sensitivity 0.705, specificity 0.922). The AUC value of PPH predicted by Fib combined with\u00a0D-D and Nw was significantly higher than that of PPH predicted by Fib (p&lt;0.05, 95\u202f% CI 0.00313\u20130.0587).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2023-0351_abs_004\">\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Fib, D-D and Nw have good predictive value for PPH of vaginal delivery, among which Fib is the best. The combination of three indexes of Fib, D-D and Nw can predict PPH more systematically and comprehensively, and provide a basis for clinical prevention and treatment of PPH.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/jpm-2023-0351","type":"journal-article","created":{"date-parts":[[2024,2,28]],"date-time":"2024-02-28T07:50:25Z","timestamp":1709106625000},"page":"478-484","source":"Crossref","is-referenced-by-count":2,"title":["The value of fibrinogen combined with D-dimer and neonatal weight in predicting postpartum hemorrhage in vaginal delivery"],"prefix":"10.1515","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6113-9853","authenticated-orcid":false,"given":"Yanke","family":"Zou","sequence":"first","affiliation":[{"name":"Department of Cardiology , Army Medical Center of PLA , Chongqing , P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4357-2159","authenticated-orcid":false,"given":"Shuai","family":"Zeng","sequence":"additional","affiliation":[{"name":"Department of Laboratory Pathology , Unit 32280 of the People\u2019s Liberation Army , Leshan City , Sichuan Province , P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Changxiao","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Army Medical Center of PLA , Chongqing , P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ling","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Health Statistics , Army Military Medical University , Chongqing , P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Army Medical Center of PLA , Chongqing , P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2024,2,29]]},"reference":[{"key":"2024060107420457157_j_jpm-2023-0351_ref_001","doi-asserted-by":"crossref","unstructured":"Dahlke, JD, Mendez-Figueroa, H, Maggio, L, Hauspurg, AK, Sperling, JD, Chauhan, SP, et al.. Prevention and management of postpartum hemorrhage: a comparison of 4 national guidelines. Am J Obstet Gynecol 2015;213:71\u20136. https:\/\/doi.org\/10.1016\/j.ajog.2015.02.023.","DOI":"10.1016\/j.ajog.2015.02.023"},{"key":"2024060107420457157_j_jpm-2023-0351_ref_002","doi-asserted-by":"crossref","unstructured":"Bienstock, JL, Eke, AC, Hueppchen, NA. Postpartum hemorrhage. 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