{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T03:13:48Z","timestamp":1767237228127},"reference-count":18,"publisher":"Walter de Gruyter GmbH","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,3,25]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_jpm-2023-0406_abs_001\">\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>Although the relationship between maternal viral infections and fetal growth restriction (FGR) is well established, the association between SARS-CoV-2 infection in pregnancy and FGR remains unclear. We investigated the association between SARS-CoV-2 infection in pregnancy and FGR at a single county hospital.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2023-0406_abs_002\">\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We performed a prospective cohort study with cohorts matched by gestational age and month of SARS-CoV-2 PCR testing between April 2020 and July 2022. Individuals were included if they had a SARS-CoV-2 PCR testing up to 32\u00a0weeks of gestation and had a third trimester ultrasound. Primary outcome was a diagnosis of FGR, while secondary outcomes were rates of preeclampsia, small for gestational age (SGA) and birthweight. Univariate analyses, chi-square test and logistic regression were used for analysis.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2023-0406_abs_003\">\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Our cohorts constituted of 102 pregnant individuals with a positive SARS-CoV-2 PCR test result and 103 pregnant individuals with a negative SARS-CoV-2 PCR test result in pregnancy. FGR rates were 17.8\u202f% and 19.42\u202f% among positive and negative SARS-CoV-2 cohorts respectively. While a statistical difference in preeclampsia rates was noted (34.31\u202f% vs. 21.36\u202f%, p=0.038) between cohorts, odds of getting preeclampsia based on SARS-CoV-2 test result was not significant (aOR 1.01, CI=0.97\u20131.01, p=0.75). No statistical difference was noted in demographics, FGR and SGA rates, and birthweight.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2023-0406_abs_004\">\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Our findings suggest no association between SARS-CoV-2 infection in pregnancy and FGR at a single institution. Our results validate emerging data that additional fetal growth ultrasonographic assessment is not indicated solely based on SARS-CoV-2 infection status.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/jpm-2023-0406","type":"journal-article","created":{"date-parts":[[2023,12,31]],"date-time":"2023-12-31T11:20:33Z","timestamp":1704021633000},"page":"317-321","source":"Crossref","is-referenced-by-count":5,"title":["The association between parental SARS-CoV-2 infection in pregnancy and fetal growth restriction"],"prefix":"10.1515","volume":"52","author":[{"given":"Melanie","family":"Mitta","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology , Emory University School of Medicine , Atlanta , GA , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lauren","family":"Holt","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Emory University School of Medicine , Atlanta , GA , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suchitra","family":"Chandrasekaran","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Emory University School of Medicine , Atlanta , GA , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolynn","family":"Dude","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Emory University School of Medicine , Atlanta , GA , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2024,1,1]]},"reference":[{"key":"2024030611333441905_j_jpm-2023-0406_ref_001","doi-asserted-by":"crossref","unstructured":"Kumar, D, Verma, S, Mysorekar, IU. 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