{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T08:52:14Z","timestamp":1773219134625,"version":"3.50.1"},"reference-count":31,"publisher":"Walter de Gruyter GmbH","issue":"1","license":[{"start":{"date-parts":[[2024,10,30]],"date-time":"2024-10-30T00:00:00Z","timestamp":1730246400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,1,29]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_jpm-2024-0153_abs_001\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Determine obstetrical and neonatal outcomes in neonates with major congenital heart disease (CHD) delivered at a level IV neonatal intensive care units (NICU) center lacking onsite pediatric cardiac surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jpm-2024-0153_abs_002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A 10-year retrospective review of all neonates admitted to our level IV NICU, with CHD between January 1st, 2011 and December 31st, 2021. Births and NICU charts were cross queried with those from our perinatal center which include pediatric cardiology records. Terminations and stillbirths were excluded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jpm-2024-0153_abs_003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 285 neonates with major CHD and 78 with\u00a0minor defects were included. In the major CHD group, 82.8\u202f% had an isolated cardiac anomaly and 17.2\u202f% had an extracardiac anomaly. Type of extracardiac anomaly had no\u00a0impact on neonatal survival. Prenatal diagnosis of aneuploidy did not impact survival in major CHD. Truncus arteriosus had the highest NICU mortality at 34.0\u202f% followed by hypoplastic left heart syndrome (HLHS) at 31.6\u202f%. Double outlet right ventricle with transposition of the great vessels and interrupted aortic arch (both types) had a 25\u202f% mortality. Neonates with truncus arteriosus and total anomalous pulmonary venous returns were likely to have 5-min Apgar score&lt;7. Transfer rate of neonates with major CHD for cardiac surgery was 58.6\u202f%. Of those 81.5\u202f% were discharged home, 14.3\u202f% expired before discharge, and 1\u202f% were transferred elsewhere post-operatively for higher level of care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jpm-2024-0153_abs_004\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Neonates with major CHD can deliver safely at a level IV NICU lacking onsite pediatric cardiac surgery. Our neonatal mortality was high for HLHS and truncus arteriosus, however comparable to other centers with proximate pediatric cardiac surgery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1515\/jpm-2024-0153","type":"journal-article","created":{"date-parts":[[2024,10,29]],"date-time":"2024-10-29T06:20:38Z","timestamp":1730182838000},"page":"58-66","source":"Crossref","is-referenced-by-count":0,"title":["Contemporary prenatal diagnosis of congenital heart disease in a regional perinatal center lacking onsite pediatric cardiac surgery: obstetrical and neonatal outcomes"],"prefix":"10.1515","volume":"53","author":[{"given":"Deena","family":"Elkafrawi","sequence":"first","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology , 12302 SUNY Upstate Medical University , Syracuse , NY , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danielle","family":"Passafiume","sequence":"additional","affiliation":[{"name":"12302 SUNY Upstate Medical University School of Medicine , Syracuse , NY , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9236-2468","authenticated-orcid":false,"given":"Michelle","family":"Blomgren","sequence":"additional","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology , 12302 SUNY Upstate Medical University , Syracuse , NY , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pamela","family":"Parker","sequence":"additional","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology , 12302 SUNY Upstate Medical University , Syracuse , NY , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven","family":"Gross","sequence":"additional","affiliation":[{"name":"Department of Pediatrics , 12302 SUNY Upstate Medical University , Syracuse , NY , USA"},{"name":"Department of Neonatology , Crouse Hospital , Syracuse , NY , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Pediatrics , 12302 SUNY Upstate Medical University , Syracuse , NY , USA"},{"name":"Department of Neonatology , Crouse Hospital , Syracuse , NY , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Silverman","sequence":"additional","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology , 12302 SUNY Upstate Medical University , Syracuse , NY , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dimitrios","family":"Mastrogiannis","sequence":"additional","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology , 12302 SUNY Upstate Medical University , Syracuse , NY , USA"},{"name":"Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology and Women\u2019s Health , Montefiore Medical Center Albert Einstein College of Medicine , Bronx , NY , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2024,10,30]]},"reference":[{"key":"2026031010583756455_j_jpm-2024-0153_ref_001","doi-asserted-by":"crossref","unstructured":"van der Linde, D, Konings, EEM, Slager, MA, Witsenburg, M, Helbing, WA, Takkenberg, JJM, et al.. 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