{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T16:46:19Z","timestamp":1779900379231,"version":"3.53.1"},"reference-count":30,"publisher":"Walter de Gruyter GmbH","issue":"2","license":[{"start":{"date-parts":[[2024,12,9]],"date-time":"2024-12-09T00:00:00Z","timestamp":1733702400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,2,25]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_jpm-2024-0427_abs_001\">\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>This study investigates the relationship between the cerebro-placental ratio (CPR) measured at 40+0\u00a0weeks\u2019 gestation and perinatal outcomes to determine a CPR cut-off that may justify induction of labor at term in appropriately grown fetuses (AGA). Although CPR is used for monitoring growth-restricted fetuses, its role in guiding labor induction decisions for AGA pregnancies at term remains unclear.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2024-0427_abs_002\">\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A retrospective cohort study was conducted using data from 491 singleton pregnancies with intended vaginal deliveries between 2015 and 2021. CPR was assessed at the actual estimated date of delivery (40+0\u00a0weeks\u2019 gestation). Adverse pregnancy outcome (APO) as the primary endpoint was defined by admission to neonatal intensive care unit (NICU), umbilical cord blood pH&lt;7.1, 5-min APGAR&lt;7 or interventions-due-to-fetal-distress during labor (IDFD=vaginal-operative delivery or emergency caesarean section).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2024-0427_abs_003\">\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>APO nearly doubled (adjOR 1.7; CI 1.007\u20132.905) when CPR was below our calculated cut-off of 1.269 (18.4 vs. 32.3\u202f%, p=0.002) and NICU admissions (4.8 vs. 11.1\u202f%, p=0.020) and IDFD (12.5 vs. 21.2\u202f%, p=0.027) significantly increased. The positive predictive value for the presence of APO using our cut-off was 32.4\u202f%, and the negative predictive value 81.6\u202f%.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2024-0427_abs_004\">\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Our data confirm a predictive value of a reduced CPR at term with impaired perinatal outcome. The cut-off of CPR&lt;1.269 may guide decision-making regarding induction of labor. Further prospective studies are needed to confirm these findings.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/jpm-2024-0427","type":"journal-article","created":{"date-parts":[[2024,12,6]],"date-time":"2024-12-06T05:16:52Z","timestamp":1733462212000},"page":"188-195","source":"Crossref","is-referenced-by-count":2,"title":["The importance of the cerebro-placental ratio at term for predicting adverse perinatal outcomes in appropriate for gestational age fetuses"],"prefix":"10.1515","volume":"53","author":[{"given":"Hannah","family":"Josten","sequence":"first","affiliation":[{"name":"Department of Obstetrics , University Hospital Jena , Jena , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yvonne","family":"Heimann","sequence":"additional","affiliation":[{"name":"Department of Obstetrics , University Hospital Jena , Jena , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Lehmann","sequence":"additional","affiliation":[{"name":"Institute of Medical Statistics and Computer Science, University Hospital Jena, Friedrich Schiller University Jena , Jena , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ekkehard","family":"Schleu\u00dfner","sequence":"additional","affiliation":[{"name":"Department of Obstetrics , University Hospital Jena , Jena , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3553-4056","authenticated-orcid":false,"given":"Tanja","family":"Groten","sequence":"additional","affiliation":[{"name":"Department of Obstetrics , University Hospital Jena , Jena , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Friederike","family":"Weschenfelder","sequence":"additional","affiliation":[{"name":"Department of Obstetrics , University Hospital Jena , Jena , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2024,12,9]]},"reference":[{"key":"2025031310143176386_j_jpm-2024-0427_ref_001","doi-asserted-by":"crossref","unstructured":"Baschat, AA, Gembruch, U, Reiss, I, Gortner, L, Weiner, CP, Harman, CR. 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