{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T15:50:45Z","timestamp":1784908245556,"version":"3.55.0"},"reference-count":21,"publisher":"Walter de Gruyter GmbH","issue":"7","license":[{"start":{"date-parts":[[2025,5,22]],"date-time":"2025-05-22T00:00:00Z","timestamp":1747872000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,9,25]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_jpm-2024-0534_abs_001\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate the endometrium using multi-vessel blood flow ultrasound parameters and explore their potential utility in predicting pregnancy outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jpm-2024-0534_abs_002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A total of 205 women were included in the study. Transvaginal three-dimensional ultrasound was used to evaluate luteal phase endometrial thickness, volume, and three-dimensional power Doppler blood flow parameters of the endometrium (vascularization index [VI], flow index [FI], and vascularization flow index [VFI]), as well as the endometrial microvascular vascularization index (VI\n                      <jats:sub>MV<\/jats:sub>\n                      ). Additionally, the systolic\/diastolic ratio (S\/D), pulsatility index (PI), and resistance index (RI) of the bilateral uterine arteries were measured. Based on pregnant outcomes, participants were divided into two groups: a clinical pregnancy group and a non-pregnancy group, and ultrasound parameters were compared between these groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jpm-2024-0534_abs_003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Women in the clinical pregnancy group showed significantly higher levels of endometrial FI, VI, VFI, and VI\n                      <jats:sub>MV<\/jats:sub>\n                      compared to those in the non-pregnancy group (p&lt;0.05). Conversely, the S\/D, PI, RI, and mean levels of bilateral uterine arteries were significantly lower in the pregnancy group than in the non-pregnancy group (p&lt;0.05). VI\n                      <jats:sub>MV<\/jats:sub>\n                      (area under the ROC curve [AUC] 0.869; sensitivity 92.2\u202f%, specificity 68.8\u202f%), VFI (AUC 0.761; sensitivity 96.9\u202f%, specificity 53.9\u202f%), FI (AUC 0.707; sensitivity 79.7\u202f%, specificity 46.1\u202f%), and VI (AUC 0.637; sensitivity 90.6\u202f%, specificity 51.8\u202f%) all showed a significant strong positive correlation with endometrial thickness (r&gt;0, p&lt;0.05), indicating their role in predicting pregnancy.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jpm-2024-0534_abs_004\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Multi-vessel blood flow parameters reflect the endometrial blood perfusion state and are closely associated with the likelihood of achieving a successful pregnancy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1515\/jpm-2024-0534","type":"journal-article","created":{"date-parts":[[2025,5,21]],"date-time":"2025-05-21T13:49:53Z","timestamp":1747835393000},"page":"827-834","source":"Crossref","is-referenced-by-count":5,"title":["Utility of endometrial multi-vessel blood flow ultrasound parameters in predicting pregnancy outcomes"],"prefix":"10.1515","volume":"53","author":[{"given":"Cai-Cha","family":"Yu","sequence":"first","affiliation":[{"name":"Department of Gynecology & Obstetrics Ultrasonography , Wenzhou Peoples\u2019Hospital , Wenzhou , Zhejiang , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia-Jia","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Gynecology & Obstetrics Ultrasonography , Wenzhou Peoples\u2019Hospital , Wenzhou , Zhejiang , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Jiao","sequence":"additional","affiliation":[{"name":"Department of Gynecology & Obstetrics Ultrasonography , Wenzhou Peoples\u2019Hospital , Wenzhou , Zhejiang , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaosi","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Gynecology & Obstetrics Ultrasonography , Wenzhou Peoples\u2019Hospital , Wenzhou , Zhejiang , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yin-Qing","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Geriatric , Wenzhou Yining Geriatric Hospital , Wenzhou , Zhejiang , China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2025,5,22]]},"reference":[{"key":"2026051215142317590_j_jpm-2024-0534_ref_001","unstructured":"Quan, ZW, Liu, XX. 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