{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,28]],"date-time":"2026-06-28T11:29:29Z","timestamp":1782646169139,"version":"3.54.5"},"reference-count":41,"publisher":"Walter de Gruyter GmbH","issue":"1","license":[{"start":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T00:00:00Z","timestamp":1763337600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,23]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_jpm-2025-0329_abs_001\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate the diagnostic accuracy of maternal characteristics, computerized cardiotocography (cCTG), maternal hemodynamics, and fetal Doppler in predicting adverse perinatal outcomes (APO) in healthy term pregnancies before labor\u00a0onset.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jpm-2025-0329_abs_002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this prospective observational study, 395 term pregnant women were enrolled. Data on obstetric history, cCTG, maternal hemodynamics, and fetal ultrasound were collected. Women undergoing labor induction were excluded. The primary endpoint was a composite APO, defined as cesarean or operative vaginal delivery due to pathological CTG, 5-min Apgar &lt;7, umbilical artery pH\u00a0&lt;7.1 and\/or base excess &gt;12\u202fmmol\/L, or NICU admission. A secondary outcome, \u201cobjective APO\u201d, excluded operative delivery for pathological CTG. Logistic regression analyses were performed to assess predictors of\u00a0APO.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jpm-2025-0329_abs_003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 307 women with spontaneous labor, 41 (13.36\u202f%) experienced a composite APO. These women were less often multiparous (7.32 vs. 27.07\u202f%, p=0.01), had higher systemic vascular resistance [SVR: 1,353 (1,209\u20131,498) vs. 1,249 (1,071\u20131,438)\u202fdyn\u202fs\u202fcm\n                      <jats:sup>\u22125<\/jats:sup>\n                      , p=0.01], and lower short-term variability [STV: 7.5 (6.2\u201310.0) vs. 9.1 (7.6\u201311.0)\u202fms, p&lt;0.01]. Fetal Doppler indices, including cerebro-placental ratio, showed no significant differences. ROC analysis identified SVR &gt;1,135\u202fdyn\u202fs\u202fcm\n                      <jats:sup>\u22125<\/jats:sup>\n                      (OR 6.92, 95\u202f% CI 2.08\u201323.03) and STV\u00a0\u22647\u202fms (OR 3.95, 95\u202f% CI 1.97\u20137.92), as optimal predictors. Multivariate analysis confirmed STV, SVR, and parity as independent predictors. In the secondary analysis of \u201cobjective APO\u201d, both SVR and STV remained significant predictors, and the multivariable model demonstrated excellent discrimination [AUC 0.931 (95\u202f% CI 0.896\u20130.957)].\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jpm-2025-0329_abs_004\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In term pregnancies, maternal hemodynamic assessment and cCTG performed before labor may improve the identification of women at increased risk of\u00a0APO.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1515\/jpm-2025-0329","type":"journal-article","created":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T05:57:56Z","timestamp":1763359076000},"page":"61-71","source":"Crossref","is-referenced-by-count":3,"title":["The impact of maternal cardiovascular status prior to labor on birth outcomes: an observational study"],"prefix":"10.1515","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4419-659X","authenticated-orcid":false,"given":"Daniele","family":"Farsetti","sequence":"first","affiliation":[{"name":"9318 University of Rome Tor Vergata , Rome , Italy"},{"name":"Department of Obstetrics and Gynecology , Policlinico Casilino , Rome , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Pometti","sequence":"additional","affiliation":[{"name":"9318 University of Rome Tor Vergata , Rome , Italy"},{"name":"Department of Obstetrics and Gynecology , Policlinico Casilino , Rome , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulio Maria","family":"Natali","sequence":"additional","affiliation":[{"name":"9318 University of Rome Tor Vergata , Rome , Italy"},{"name":"Department of Obstetrics and Gynecology , Policlinico Casilino , Rome , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Greta","family":"Carta","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Policlinico Casilino , Rome , Italy"},{"name":"University of Cagliari , Cagliari , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Livia","family":"Pieri","sequence":"additional","affiliation":[{"name":"9318 University of Rome Tor Vergata , Rome , Italy"},{"name":"Department of Obstetrics and Gynecology , Policlinico Casilino , Rome , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benedetta","family":"Laudonio","sequence":"additional","affiliation":[{"name":"9318 University of Rome Tor Vergata , Rome , Italy"},{"name":"Department of Obstetrics and Gynecology , Policlinico Casilino , Rome , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davide Archelao","family":"Dess\u00ec","sequence":"additional","affiliation":[{"name":"9318 University of Rome Tor Vergata , Rome , Italy"},{"name":"Department of Obstetrics and Gynecology , Policlinico Casilino , Rome , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Vasapollo","sequence":"additional","affiliation":[{"name":"9318 University of Rome Tor Vergata , Rome , Italy"},{"name":"Department of Obstetrics and Gynecology , Policlinico Casilino , Rome , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gian Paolo","family":"Novelli","sequence":"additional","affiliation":[{"name":"Department of Cardiology , Fondazione PTV Policlinico Tor Vergata , Rome , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herbert","family":"Valensise","sequence":"additional","affiliation":[{"name":"9318 University of Rome Tor Vergata , Rome , Italy"},{"name":"Department of Obstetrics and Gynecology , Policlinico Casilino , Rome , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2025,11,17]]},"reference":[{"key":"2026053006093735739_j_jpm-2025-0329_ref_001","doi-asserted-by":"crossref","unstructured":"Essex, HN, Green, J, Baston, H, Pickett, KE. 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