{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T03:00:31Z","timestamp":1781319631582,"version":"3.54.1"},"reference-count":18,"publisher":"Walter de Gruyter GmbH","issue":"5","license":[{"start":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T00:00:00Z","timestamp":1773100800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6,24]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_jpm-2025-0416_abs_001\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Foetal macrosomia is a significant obstetric problem that can lead to serious maternal\/neonatal complications. The aim of this study was to determine which of the 75\u202fg oral glucose tolerance test (OGTT) glucose values\u00a0\u2013\u00a0fasting, first-hour, or second-hour\u00a0\u2013\u00a0most strongly predicts foetal macrosomia in non-diabetic patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jpm-2025-0416_abs_002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This cross-sectional study prospectively screened 1,047 pregnant women who underwent a 75\u202fg OGTT. Women with pregestational or gestational diabetes mellitus (GDM) were excluded from the main analysis. A total of 185\u00a0non-diabetic women were included. Among the included patients, those who delivered macrosomic foetuses constituted Group 1 (n=16), while those who delivered normal birth weight infants constituted Group 2 (n=169). Fasting, first-hour, and second-hour glucose values from the 75\u202fg OGTT were compared between the groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jpm-2025-0416_abs_003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>No statistically significant differences were found between the two groups in terms of demographic variables (p&gt;0.05). The mean fasting glucose values in Groups 1 and 2 were 77.75 and 76.11\u202fmg\/dL, respectively (p=0.42), the mean first-hour glucose values were 116.25 and 111.51\u202fmg\/dL, respectively (p=0.43), and the mean second-hour glucose values were 104.38 and 95.19\u202fmg\/dL, respectively (p=0.04). Receiver operating characteristic (ROC) curve analysis was performed for the second-hour glucose concentration, with an AUC of 0.675, and a threshold of 99.5\u202fmg\/dL was established.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jpm-2025-0416_abs_004\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The second-hour glucose value of the 75\u202fg OGTT may be a marker for foetal macrosomia in nondiabetic patients. These findings suggest that when the second-hour glucose value exceeds 99.5\u202fmg\/dL, foetal macrosomia may develop.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1515\/jpm-2025-0416","type":"journal-article","created":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T13:07:26Z","timestamp":1773061646000},"page":"874-880","source":"Crossref","is-referenced-by-count":0,"title":["Association between oral glucose tolerance test (OGTT) glucose levels and fetal macrosomia in non-diabetic women"],"prefix":"10.1515","volume":"54","author":[{"given":"Taha Yasin","family":"Bayram","sequence":"first","affiliation":[{"name":"653123 Obstetrics and Gynecology Clinic, Beytussebap State Hospital , Sirnak , T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reyhan","family":"Aslancan Bayram","sequence":"additional","affiliation":[{"name":"653123 Obstetrics and Gynecology Clinic, Beytussebap State Hospital , Sirnak , T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8005-2887","authenticated-orcid":false,"given":"Osman Murat","family":"Guler","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Clinic, Kapakl\u0131 State Hospital , Tekirdag , T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Burak","family":"Yucel","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Clinic, Basaksehir Cam and Sakura City Hospital , Istanbul , T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2026,3,10]]},"reference":[{"key":"2026061302442416121_j_jpm-2025-0416_ref_001","doi-asserted-by":"crossref","unstructured":"Macrosomia: ACOG practice bulletin summary, number 216. 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