{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T08:13:34Z","timestamp":1790324014546,"version":"4.1.0"},"reference-count":59,"publisher":"Walter de Gruyter GmbH","license":[{"start":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T00:00:00Z","timestamp":1790553600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_jpm-2026-0090_abs_001\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The extracellular matrix of chorionic villi is an important factor ensuring the structural and functional viability of the placenta. The aim of the study was to compare the collagen-elastic frame of different types of chorionic villi in normal and pathological pregnancy in the I\u2013III trimesters.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jpm-2026-0090_abs_002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We compared placentas of the I, II and III trimesters in pathological pregnancies associated with (1) fetal and placental malformations\/genetic aberrations\/dysgenesis, as well as (2) chronic fetoplacental hypoxia\/asphyxia with the group of placentas from uncomplicated pregnancies of the appropriate gestational period. The study was performed by light microscopy on sections stained by Weigert (elastic fibers), Masson\u2019s trichrome (type I collagen) and Gomori\u2019s silver staining (type III collagen).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jpm-2026-0090_abs_003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Physiological pregnancies showed stage-specific remodeling of the collagen-elastic frame. The dominance of the reticular organization of the stroma decreased as the villi matured. At the same time, the proportion of collagen fibrillar structures increased and was accompanied by the relative decrease in the number of subtrophoblastic elastic fibers in the distal, mainly terminal villi. The persistence of diffuse fibrillar and elastic stromal patterns in the terminal villi of full-term placentas was observed with delayed maturation of the villi and diabetes-associated changes in the placenta. Peripheral granular pattern of elastic fiber distribution in aberrant hydropic and dysmorphic villi was detected in fetal and placental malformations, genetic abnormalities, and dysgenesis. A diffuse homogeneous type I collagen pattern was associated with impaired fetoplacental unit formation and hypoxic damage.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jpm-2026-0090_abs_004\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Placentas of the I\u2013III trimester with disorders of the formation of the fetoplacental unit, dysmetabolic conditions and hypoxic damage demonstrate patterns of remodeling of the collagen-elastic framework of chorionic villi, which differ from normal placentas of the corresponding gestational age.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1515\/jpm-2026-0090","type":"journal-article","created":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T07:55:43Z","timestamp":1790322943000},"source":"Crossref","is-referenced-by-count":0,"title":["Diagnostic significance of histopathological assessment of villous extracellular matrix in normal and pathological placentas"],"prefix":"10.1515","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8598-1829","authenticated-orcid":false,"given":"Leila M.","family":"Stabayeva","sequence":"first","affiliation":[{"name":"Department of Morphology , Karaganda Medical University , Karaganda , Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0674-2323","authenticated-orcid":false,"given":"Nurzhamal N.","family":"Kulmaganbetova","sequence":"additional","affiliation":[{"name":"Department of Morphology , Karaganda Medical University , Karaganda , Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8975-3612","authenticated-orcid":false,"given":"Yevgeniy K.","family":"Kamyshanskiy","sequence":"additional","affiliation":[{"name":"Department of Morphology , Karaganda Medical University , Karaganda , Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8125-6643","authenticated-orcid":false,"given":"Zhanna T.","family":"Amirbekova","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Gynecology and Perinatology , Karaganda Medical University , Karaganda , Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6264-1872","authenticated-orcid":false,"given":"Raihan Zh.","family":"Nygizbayeva","sequence":"additional","affiliation":[{"name":"Department of Morphology , Karaganda Medical University , Karaganda , Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3494-8612","authenticated-orcid":false,"given":"Sergey N.","family":"Zhuravlev","sequence":"additional","affiliation":[{"name":"Department of Morphology , Karaganda Medical University , Karaganda , Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0410-817X","authenticated-orcid":false,"given":"Ekaterina","family":"Kakhiani","sequence":"additional","affiliation":[{"name":"S.N. Davydov Department of Obstetrics and Gynecology , Institute of Pediatrics, I.I. Mechnikov North-Western State Medical University , Saint Petersburg , Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2026,9,28]]},"reference":[{"key":"2026092507553739998_j_jpm-2026-0090_ref_001","doi-asserted-by":"crossref","unstructured":"Kramer, AC, Jansson, T, Bale, TL, Powell, TL. Maternal-fetal cross-talk via the placenta: influence on offspring development and metabolism. Development 2023;150:dev202088. https:\/\/doi.org\/10.1242\/dev.202088.","DOI":"10.1242\/dev.202088"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_002","doi-asserted-by":"crossref","unstructured":"Godfrey, KM. The role of the placenta in fetal programming-a review. Placenta 2002;23:S20\u20137. https:\/\/doi.org\/10.1053\/plac.2002.0773.","DOI":"10.1053\/plac.2002.0773"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_003","doi-asserted-by":"crossref","unstructured":"Myatt, L. Placental adaptive responses and fetal programming. J Physiol 2006;572:25\u201330. https:\/\/doi.org\/10.1113\/jphysiol.2006.104968.","DOI":"10.1113\/jphysiol.2006.104968"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_004","doi-asserted-by":"crossref","unstructured":"Burton, GJ, Jauniaux, E. The human placenta: new perspectives on its formation and function during early pregnancy. Proc Biol Sci 2023;290:20230191. https:\/\/doi.org\/10.1098\/rspb.2023.0191.","DOI":"10.1098\/rspb.2023.0191"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_005","doi-asserted-by":"crossref","unstructured":"Khorami-Sarvestani, S, Vanaki, N, Shojaeian, S, Zarnani, K, Stensballe, A, Jeddi-Tehrani, M, et al.. Placenta: an old organ with new functions. Front Immunol 2024;15:1385762. https:\/\/doi.org\/10.3389\/fimmu.2024.1385762.","DOI":"10.3389\/fimmu.2024.1385762"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_006","doi-asserted-by":"crossref","unstructured":"Lobo, SE, Leonel, LC, Miranda, CM, Coelho, TM, Ferreira, GA, Mess, A, et al.. The placenta as an organ and a source of stem cells and extracellular matrix: a review. Cells Tissues Organs 2016;201:239\u201352. https:\/\/doi.org\/10.1159\/000443636.","DOI":"10.1159\/000443636"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_007","doi-asserted-by":"crossref","unstructured":"Greenbaum, S, Averbukh, I, Soon, E, Rizzuto, G, Baranski, A, Greenwald, NF, et al.. A spatially resolved timeline of the human maternal\u2013fetal interface. 2023. Nature;619:595\u2013605. https:\/\/doi.org\/10.1038\/s41586-023-06298-9.","DOI":"10.1038\/s41586-023-06298-9"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_008","doi-asserted-by":"crossref","unstructured":"Franczyk, M, Lopucki, M, Stachowicz, N, Morawska, D, Kankofer, M. Extracellular matrix proteins in healthy and retained placentas, comparing hemochorial and synepitheliochorial placentas. Placenta 2017;50:19\u201324. https:\/\/doi.org\/10.1016\/j.placenta.2016.12.014.","DOI":"10.1016\/j.placenta.2016.12.014"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_009","doi-asserted-by":"crossref","unstructured":"Rossi, F, Luppi, S, Fejza, A, Giolo, E, Ricci, G, Andreuzzi, E. Extracellular matrix and pregnancy: functions and opportunities caught in the net. Reprod Biol Endocrinol 2025;23:24. https:\/\/doi.org\/10.1186\/s12958-025-01348-5.","DOI":"10.1186\/s12958-025-01348-5"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_010","doi-asserted-by":"crossref","unstructured":"O\u2019Connor, BB, Pope, BD, Peters, MM, Ris-Stalpers, C, Parker, KK. The role of extracellular matrix in normal and pathological pregnancy: future applications of microphysiological systems in reproductive medicine. Exp Biol Med (Maywood) 2020;245:1163\u201374. https:\/\/doi.org\/10.1177\/1535370220938741.","DOI":"10.1177\/1535370220938741"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_011","doi-asserted-by":"crossref","unstructured":"Amenta, PS, Gay, S, Vaheri, A, Martinez-Hernandez, A. The extracellular matrix is an integrated unit: ultrastructural localization of collagen types I, III, IV, V, VI, fibronectin, and laminin in human term placenta. Collagen Relat Res 1986;6:125\u201352. https:\/\/doi.org\/10.1016\/s0174-173x(86)80021-8.","DOI":"10.1016\/S0174-173X(86)80021-8"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_012","doi-asserted-by":"crossref","unstructured":"Sati, L, Demir, AY, Sarikcioglu, L, Demir, R. Arrangement of collagen fibers in human placental stem villi. Acta Histochem 2008;110:371\u20139. https:\/\/doi.org\/10.1016\/j.acthis.2007.11.006.","DOI":"10.1016\/j.acthis.2007.11.006"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_013","unstructured":"Rukosuev, VS, Fokin, EI, Milovanov, AP. Immunofluorestsentnoe izuchenie \u00e9ktratselliuliarnogo matriksa platsenty cheloveka. Ontogenez 1989;20:171\u20138."},{"key":"2026092507553739998_j_jpm-2026-0090_ref_014","doi-asserted-by":"crossref","unstructured":"Nanaev, AK, Rukosuev, VS, Milovanov, AP, Fokin, EI, Shirinski\u012d, VP. Raspredelenie kollagena III i IV tipov v vorsinakh platsenty cheloveka [Distribution of collagen types III and IV in human placental villi]. Biull Eksp Biol Med. 1989;107:247\u201350.","DOI":"10.1007\/BF00833825"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_015","unstructured":"Mukhammad, I, Tussupbekova, MM. Macroscopic morphological changes of the placenta associated with preeclampsia. Med Ecol 2020:107\u201315."},{"key":"2026092507553739998_j_jpm-2026-0090_ref_016","unstructured":"Johnson, PM, Faulk, WP. Immunological studies of human placentae: identification and distribution of proteins in immature chorionic villi. Immunology 1978;34:1027\u201335."},{"key":"2026092507553739998_j_jpm-2026-0090_ref_017","doi-asserted-by":"crossref","unstructured":"Barros, JS, Gon\u00e7alves, CA, Bairos, VA. Elastic fibers in the human placenta. Arch Gynecol Obstet 2003;267:208\u201312. https:\/\/doi.org\/10.1007\/s00404-002-0314-7.","DOI":"10.1007\/s00404-002-0314-7"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_018","doi-asserted-by":"crossref","unstructured":"Graf, R, Neudeck, H, Gossrau, R, Vetter, K. Elastic fibers are an essential component of human placental stem villous stroma and an integrated part of the perivascular contractile sheath. Cell Tissue Res 1996;283:133\u201341. https:\/\/doi.org\/10.1007\/s004410050521.","DOI":"10.1007\/s004410050521"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_019","doi-asserted-by":"crossref","unstructured":"Feng, Y, Chen, X, Wang, H, Chen, X, Lan, Z, Li, P, et al.. Collagen I induces preeclampsia-like symptoms by suppressing proliferation and invasion of trophoblasts. Front Endocrinol (Lausanne) 2021;12:664766. https:\/\/doi.org\/10.3389\/fendo.2021.664766.","DOI":"10.3389\/fendo.2021.664766"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_020","doi-asserted-by":"crossref","unstructured":"Xu, XH, Jia, Y, Zhou, X, Xie, D, Huang, X, Jia, L, et al.. Downregulation of lysyl oxidase and lysyl oxidase-like protein 2 suppressed the migration and invasion of trophoblasts by activating the TGF-\u03b2\/collagen pathway in preeclampsia. Exp Mol Med 2019;51:1\u201312. https:\/\/doi.org\/10.1038\/s12276-019-0211-9.","DOI":"10.1038\/s12276-019-0211-9"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_021","doi-asserted-by":"crossref","unstructured":"Chen, CP, Aplin, JD. Placental extracellular matrix: gene expression, deposition by placental fibroblasts and the effect of oxygen. Placenta 2003;24:316\u201325. https:\/\/doi.org\/10.1053\/plac.2002.0904.","DOI":"10.1053\/plac.2002.0904"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_022","doi-asserted-by":"crossref","unstructured":"Ortega, MA, As\u00fansolo, \u00c1, Fraile-Mart\u00ednez, O, Sainz, F, Saez, MA, Bravo, C, et al.. An increase in elastogenic components in the placental villi of women with chronic venous disease during pregnancy is associated with decreased EGFL7 expression level. Mol Med Rep 2021;24:556. https:\/\/doi.org\/10.3892\/mmr.2021.12195.","DOI":"10.3892\/mmr.2021.12195"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_023","unstructured":"Ortega, MA, As\u00fansolo, \u00c1, \u00c1lvarez-Rocha, MJ, Romero, B, De Le\u00f3n-Luis, J, \u00c1lvarez-Mon, M, et al.. Remodelling of collagen fibers in the placentas of women with venous insufficiency during pregnancy. Histol Histopathol 2018;33:567\u201376. https:\/\/doi.org\/10.14670\/HH-11-948."},{"key":"2026092507553739998_j_jpm-2026-0090_ref_024","doi-asserted-by":"crossref","unstructured":"Rahat, B, Sharma, R, Bagga, R, Hamid, A, Kaur, J. Imbalance between matrix metalloproteinases and their tissue inhibitors in preeclampsia and gestational trophoblastic diseases. Reproduction 2016;152:11\u201322. https:\/\/doi.org\/10.1530\/REP-16-0060.","DOI":"10.1530\/REP-16-0060"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_025","doi-asserted-by":"crossref","unstructured":"Leushner, JR, Clarson, CL. Analysis of the collagens from the fetal membranes of diabetic mothers. Placenta 1986;7:65\u201372. https:\/\/doi.org\/10.1016\/s0143-4004(86)80018-2.","DOI":"10.1016\/S0143-4004(86)80018-2"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_026","doi-asserted-by":"crossref","unstructured":"Katzman, PJ, Genest, DR. Maternal floor infarction and massive perivillous fibrin deposition: histological definitions, association with intrauterine fetal growth restriction, and risk of recurrence. Pediatr Dev Pathol 2002;5:159\u201364. https:\/\/doi.org\/10.1007\/s10024001-0195-y.","DOI":"10.1007\/s10024001-0195-y"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_027","doi-asserted-by":"crossref","unstructured":"Roman, A, Suhag, A, Berghella, V. Overview of cervical insufficiency: diagnosis, etiologies, and risk factors. Clin Obstet Gynecol 2016;59:237\u201340. https:\/\/doi.org\/10.1097\/GRF.0000000000000184.","DOI":"10.1097\/GRF.0000000000000184"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_028","doi-asserted-by":"crossref","unstructured":"ACOG Practice Bulletin No. 142. Cerclage for the management of cervical insufficiency. Obstet Gynecol 2014;123:372\u20139. https:\/\/doi.org\/10.1097\/01.AOG.0000443276.68274.cc.","DOI":"10.1097\/01.AOG.0000443276.68274.cc"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_029","doi-asserted-by":"crossref","unstructured":"Hammad, IA, Blue, NR, Allshouse, AA, Silver, RM, Gibbins, KJ, Page, JM, et al.. Umbilical cord abnormalities and stillbirth. Obstet Gynecol 2020;135:644\u201352. https:\/\/doi.org\/10.1097\/AOG.0000000000003676.","DOI":"10.1097\/AOG.0000000000003676"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_030","unstructured":"Langston, C, Kaplan, C, Macpherson, T, Manci, E, Peevy, K, Clark, B, et al.. Practice guideline for examination of the placenta: developed by the placental pathology practice guideline development task force of the college of American pathologists. Arch Pathol Lab Med 1997;121:449\u201376."},{"key":"2026092507553739998_j_jpm-2026-0090_ref_031","doi-asserted-by":"crossref","unstructured":"Tonni, G, Lituania, M, Grisolia, G, Pinto, A, Bonasoni, MP, Rizzo, G, et al.. Placental and umbilical cord anomalies detected by ultrasound as clinical risk factors of adverse perinatal outcomes. Case series review of selected conditions. Part 3: vascular anomalies of the umbilical cord and fetoplacental vascular malperfusion. J Clin Ultrasound 2025;53:863\u201379. https:\/\/doi.org\/10.1002\/jcu.23904.","DOI":"10.1002\/jcu.23904"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_032","unstructured":"Gibb, D, Arulkumaran, S. Fetal monitoring in practice, 4th ed. Churchill Livingstone, eBook: Elsevier; 2017."},{"key":"2026092507553739998_j_jpm-2026-0090_ref_033","doi-asserted-by":"crossref","unstructured":"Gazis, D, Tranidou, A, Siargkas, A, Apostolopoulou, A, Koutsouki, G, Goulis, DG, et al.. Pregestational diabetes mellitus and adverse perinatal outcomes: a systematic review and meta-analysis. J Clin Med 2025;14:4789. https:\/\/doi.org\/10.3390\/jcm14134789.","DOI":"10.3390\/jcm14134789"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_034","doi-asserted-by":"crossref","unstructured":"Laval, N, Paquette, M, Talsmat, H, Marandyuk, B, Wintermark, P, Birca, A, et al.. Exposure to maternal diabetes during pregnancy is associated with aggravated short-term neonatal and neurological outcomes following perinatal hypoxic-ischemic encephalopathy. Am J Perinatol 2024;41:e1581. https:\/\/doi.org\/10.1055\/a-2053-7904.","DOI":"10.1055\/a-2053-7904"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_035","doi-asserted-by":"crossref","unstructured":"Cnattingius, S, Lindam, A, Persson, M. Risks of asphyxia-related neonatal complications in offspring of mothers with type 1 or type 2 diabetes: the impact of maternal overweight and obesity. Diabetologia 2017;60:1244\u201351. https:\/\/doi.org\/10.1007\/s00125-017-4279-2.","DOI":"10.1007\/s00125-017-4279-2"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_036","doi-asserted-by":"crossref","unstructured":"American College of Obstetricians and Gynecologists\u2019 Committee on Practice Bulletins-Obstetrics. ACOG practice bulletin no. 201: pregestational diabetes mellitus. Obstet Gynecol 2018;132:e228\u201348. https:\/\/doi.org\/10.1097\/AOG.0000000000002960.","DOI":"10.1097\/AOG.0000000000002960"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_037","doi-asserted-by":"crossref","unstructured":"American Diabetes Association Professional Practice Committee. 2. Diagnosis and classification of diabetes: standards of care in diabetes \u20132024. Diabetes Care 2024;47:S20\u201342. https:\/\/doi.org\/10.2337\/dc24-S002.","DOI":"10.2337\/dc24-S002"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_038","doi-asserted-by":"crossref","unstructured":"Khong, TY, Mooney, EE, Ariel, I, Balmus, NC, Boyd, TK, Brundler, MA, et al.. Sampling and definitions of placental lesions: Amsterdam placental workshop group consensus statement. Arch Pathol Lab Med 2016;140:698\u2013713. https:\/\/doi.org\/10.5858\/arpa.2015-0225-CC.","DOI":"10.5858\/arpa.2015-0225-CC"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_039","doi-asserted-by":"crossref","unstructured":"Turdybekova, YG, Kopobayeva, IL, Kamyshanskiy, YK, Turmukhambetova, AA. Comparative clinical and placental pathologic characteristics in pregnancies with and without SARS-CoV-2 infection. J Perinat Med 2023;51:1179\u201388. https:\/\/doi.org\/10.1515\/jpm-2022-0371.","DOI":"10.1515\/jpm-2022-0371"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_040","doi-asserted-by":"crossref","unstructured":"Imanbayev, NM, Iztleuov, YM, Kamyshanskiy, YK, Zhumasheva, AV. Diagnostic and prognostic significance of keloid-like collagen remodeling patterns in the extracellular matrix of colorectal cancer. Pathol Oncol Res 2024;30:1611789. https:\/\/doi.org\/10.3389\/pore.2024.1611789.","DOI":"10.3389\/pore.2024.1611789"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_041","doi-asserted-by":"crossref","unstructured":"Vogel, M. Pathologie der Plazenta: sp\u00e4tschwangerschaft und fetoplazentare Einheit. In: Kl\u00f6ppel, G, Kreipe, H, Remmele, W, Dietel, M, editors. Pathologie. Berlin\/Heidelberg, Germany: Springer; 2013:541\u2013632 pp.","DOI":"10.1007\/978-3-642-04564-6_25"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_042","unstructured":"Benirschke, K, Kaufmann, P, Baergen, R. Pathology of the human placenta, 5th ed. New York: Springer; 2006."},{"key":"2026092507553739998_j_jpm-2026-0090_ref_043","doi-asserted-by":"crossref","unstructured":"Vogel, M. Atlas der morphologischen Plazentadiagnostik, 2nd ed. Heidelberg: Springer-Verlag; 1996.","DOI":"10.1007\/978-3-642-80083-2"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_044","doi-asserted-by":"crossref","unstructured":"Hookerman, BJ. Dermatopathology: an abridged compendium of words. A discussion of them and opinions about them. Part 5. Dermatol Pract Concept 2014;4:1\u20139. https:\/\/doi.org\/10.5826\/dpc.0403a01.","DOI":"10.5826\/dpc.0403a01"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_045","unstructured":"Lever\u2019s histopathology of the skin. 13th ed. Philadelphia: Wolters Kluwer; 2019."},{"key":"2026092507553739998_j_jpm-2026-0090_ref_046","doi-asserted-by":"crossref","unstructured":"Cicchetti, DV. Guidelines, criteria, and rules of thumb for evaluating normed and standardized assessment instruments in psychology. Psychol Assess 1994;6:284\u201390. https:\/\/doi.org\/10.1037\/1040-3590.6.4.284.","DOI":"10.1037\/1040-3590.6.4.284"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_047","doi-asserted-by":"crossref","unstructured":"Kaufmann, P, Stark, J, Stegner, HE. The villous stroma of the human placenta. I. The ultrastructure of fixed connective tissue cells. Cell Tissue Res 1977;177:105\u201321. https:\/\/doi.org\/10.1007\/BF00221122.","DOI":"10.1007\/BF00221122"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_048","doi-asserted-by":"crossref","unstructured":"Boyd, JD, Hamilton, WJ. The human placenta. Cambridge: Heffer & Sons LTD; 1970:228\u201339 pp.","DOI":"10.1007\/978-1-349-02807-8_15"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_049","doi-asserted-by":"crossref","unstructured":"Hofman, W. Vergleichend-morphologische Untersuchungen \u00fcber das Vorkommen elastischer Fasern in den Zottengef\u00e4\u03b2en von Geburtsplacenten. Acta Anat 1967;66:67\u201377. https:\/\/doi.org\/10.1159\/000142916.","DOI":"10.1159\/000142916"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_050","doi-asserted-by":"crossref","unstructured":"Montes, GS. Structural biology of the fibers of the collagenous and elastic systems. Cell Biol Int 1996;20:15\u201327. https:\/\/doi.org\/10.1006\/cbir.1996.0004.","DOI":"10.1006\/cbir.1996.0004"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_051","doi-asserted-by":"crossref","unstructured":"Iwahashi, M, Ooshima, A, Nakano, R. Increase in the relative level of type V collagen during development and ageing of the placenta. J Clin Pathol 1996;49:916\u201319. https:\/\/doi.org\/10.1136\/jcp.49.11.916.","DOI":"10.1136\/jcp.49.11.916"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_052","doi-asserted-by":"crossref","unstructured":"Sebire, NJ. Histopathological diagnosis of hydatidiform mole: contemporary features and clinical implications. Fetal Pediatr Pathol 2010;29:1\u201316. https:\/\/doi.org\/10.3109\/15513810903266138.","DOI":"10.3109\/15513810903266138"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_053","doi-asserted-by":"crossref","unstructured":"Gonzalez, J, Popp, M, Ocejo, S, Abreu, A, Bahmad, HF, Poppiti, R. Gestational trophoblastic disease: complete versus partial hydatidiform moles. Diseases 2024;12:159. https:\/\/doi.org\/10.3390\/diseases12070159.","DOI":"10.3390\/diseases12070159"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_054","doi-asserted-by":"crossref","unstructured":"Iwahashi, M, Muragaki, Y, Ooshima, A, Nakano, R. Decreased type III and V collagen expression in chorionic villi of hydatidiform mole. J Clin Endocrinol Metab 2001;86:3346\u201350. https:\/\/doi.org\/10.1210\/jcem.86.7.7632.","DOI":"10.1210\/jcem.86.7.7632"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_055","doi-asserted-by":"crossref","unstructured":"Stanek, J. Patterns of placental injury in congenital anomalies in second half of pregnancy. Pediatr Dev Pathol 2019;22:513\u201322. https:\/\/doi.org\/10.1177\/1093526619852869.","DOI":"10.1177\/1093526619852869"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_056","doi-asserted-by":"crossref","unstructured":"Rakheja, D, Wilson, KS, Rogers, BB. Dysmorphic villi mimicking partial mole in a case with del(18)(q21). Pediatr Dev Pathol 2004;7:546\u20138. https:\/\/doi.org\/10.1007\/s10024-004-2022-8.","DOI":"10.1007\/s10024-004-2022-8"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_057","doi-asserted-by":"crossref","unstructured":"Li, H, Shafique, K, Harper, A, Anderson, V. Fetal malformations with hydropic dysmorphic placental villi: a comprehensive pathology report. Am J Clin Pathol 2016;146:73. https:\/\/doi.org\/10.1093\/ajcp\/aqw162.011.","DOI":"10.1093\/ajcp\/aqw162.011"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_058","doi-asserted-by":"crossref","unstructured":"Thompson, BB, Holzer, PH, Kliman, HJ. Placental pathology findings in unexplained pregnancy losses. Reprod Sci 2024;31:488\u2013504. https:\/\/doi.org\/10.1007\/s43032-023-01344-3.","DOI":"10.1007\/s43032-023-01344-3"},{"key":"2026092507553739998_j_jpm-2026-0090_ref_059","doi-asserted-by":"crossref","unstructured":"Turdybekova, YG, Kopobayeva, IL, Turmukhambetova, AA, Kamyshanskiy, YK. Multi-organ dysfunction and outcomes in pregnancy associated COVID-19 infection \u2013 descriptive review of pathological findings. BMC Pregnancy Childbirth 2024;24:45. https:\/\/doi.org\/10.1186\/s12884-023-06240-x.","DOI":"10.1186\/s12884-023-06240-x"}],"container-title":["Journal of Perinatal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1515\/jpm-2026-0090\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1515\/jpm-2026-0090\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T07:56:07Z","timestamp":1790322967000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1515\/jpm-2026-0090\/html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,28]]},"references-count":59,"alternative-id":["10.1515\/jpm-2026-0090"],"URL":"https:\/\/doi.org\/10.1515\/jpm-2026-0090","relation":{},"ISSN":["0300-5577","1619-3997"],"issn-type":[{"value":"0300-5577","type":"print"},{"value":"1619-3997","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,28]]}}}