{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T16:15:27Z","timestamp":1783440927094,"version":"3.54.6"},"reference-count":24,"publisher":"Walter de Gruyter GmbH","issue":"6","license":[{"start":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T00:00:00Z","timestamp":1779667200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7,24]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_jpm-2026-0185_abs_001\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Umbilical cord blood gas analysis captures the fetal acid-base balance at birth. We aimed to investigate the effect of antenatal and perinatal parameters on the cord blood pH\u00a0and explore the association of cord pH\u00a0with postnatal outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jpm-2026-0185_abs_002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective cohort study of preterm infants born and admitted to the Neonatal Unit at King\u2019s College Hospital NHS Foundation Trust. The arterial and venous cord pH\u00a0and the difference between the venous and the arterial pH\u00a0were recorded (\u0394pH).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jpm-2026-0185_abs_003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>From 2012 to 2023, 1,598 preterm infants (849 male) were included with a median (IQR) gestational age of 33.1 (30.4\u201335.1) weeks. The median (IQR) cord arterial pH\u00a0was 7.27 (7.20\u20137.31) and cord venous pH\u00a0was 7.32 (7.27\u20137.36). The arterial pH\u00a0was significantly associated with the Apgar score at 10\u202fmin [unstandardised coefficient 0.021, 95\u202f% CI: 0.015\u20130.027, adjusted p&lt;0.001], the venous pH\u00a0with the birth weight z-score [unstandardised coefficient 0.015, 95\u202f% CI: 0.009 to 0.021, p&lt;0.001] and the \u0394pH\u00a0with the administration of intrapartum antibiotics [unstandardised coefficient 0.015, 95\u202f% CI: 0.006 to 0.025, p=0.002]. None of the indices were associated with the duration of invasive ventilation, the duration of stay or with survival to discharge from neonatal\u00a0care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jpm-2026-0185_abs_004\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Low arterial cord pH\u00a0was associated with poor perinatal adaptation, low venous cord pH\u00a0was associated with decreased fetal growth and a large difference between the two with possible perinatal infection.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1515\/jpm-2026-0185","type":"journal-article","created":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T11:03:11Z","timestamp":1779447791000},"page":"1047-1053","source":"Crossref","is-referenced-by-count":0,"title":["Perinatal determinants of the umbilical cord pH\u00a0following preterm birth"],"prefix":"10.1515","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5258-5301","authenticated-orcid":false,"given":"Theodore","family":"Dassios","sequence":"first","affiliation":[{"name":"Women and Children\u2019s Health, School of Life Course Sciences, Faculty of Life Sciences and Medicine , King\u2019s College London , London , UK"},{"name":"Neonatal Intensive Care Unit , University of Patras , Patras , Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allan","family":"Jenkinson","sequence":"additional","affiliation":[{"name":"Women and Children\u2019s Health, School of Life Course Sciences, Faculty of Life Sciences and Medicine , King\u2019s College London , London , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ravindra","family":"Bhat","sequence":"additional","affiliation":[{"name":"Neonatal Intensive Care Centre , King\u2019s College Hospital NHS Foundation Trust , London , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8672-5349","authenticated-orcid":false,"given":"Anne","family":"Greenough","sequence":"additional","affiliation":[{"name":"Women and Children\u2019s Health, School of Life Course Sciences, Faculty of Life Sciences and Medicine , King\u2019s College London , London , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikos A.","family":"Kametas","sequence":"additional","affiliation":[{"name":"Harris Birthright Research Centre for Fetal Medicine , Fetal Medicine Research Institution, King\u2019s College Hospital , London , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2026,5,25]]},"reference":[{"key":"2026070714574632840_j_jpm-2026-0185_ref_001","doi-asserted-by":"crossref","unstructured":"Practice ACO. 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