{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T20:45:45Z","timestamp":1790541945662,"version":"4.1.0"},"reference-count":18,"publisher":"Walter de Gruyter GmbH","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Objectives:<\/jats:bold>To examine whether exogenous pulmonary surfactants (exPS) substitute for or merely supplement endogenous pulmonary surfactants (enPS) by looking at sequential changes in the surfactant proteins (SP) SP-A and SP-D in alveolar pools.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold>Fourteen preterm infants with RDS treated with an artificial surfactant were compared to five normal-term infants without RDS who were treated with artificial ventilation at birth.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold>Immediately after birth, SP-A and SP-D were essentially absent in the alveolar pools of the RDS group, but were present at normal levels in the controls. Treatment with exPS apparently stimulated enPS production.<\/jats:p><jats:p><jats:bold>Conclusions:<\/jats:bold>In infants who responded well to exPS therapy, the SP concentration reached essentially normal levels within 48\u201372\u00a0h after birth.<\/jats:p>","DOI":"10.1515\/jpm.2009.100","type":"journal-article","created":{"date-parts":[[2009,6,3]],"date-time":"2009-06-03T12:27:32Z","timestamp":1244032052000},"page":"561-564","source":"Crossref","is-referenced-by-count":14,"title":["Effect of exogenous surfactant therapy on levels of pulmonary surfactant proteins A and D in preterm infants with respiratory distress syndrome"],"prefix":"10.1515","volume":"37","author":[{"given":"Young Min","family":"Bae","sequence":"first","affiliation":[{"name":"Department of Pediatrics, College of Medicine, Kyunghee University, Seoul 134-727, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chong-Woo","family":"Bae","sequence":"additional","affiliation":[{"name":"Department 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