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HSP helps in reparative processes, including the refolding of damaged proteins and the removal of irreparably damaged proteins that would initiate cellular death or apoptosis. A growing body of evidence has expanded the role of HSP and defined their role in diseases such as neurodegenerative disorders, cancer, ischemic heart disease and kidney diseases. The protective role of HSP in ischemic renal injury has been described and HSP impairment has been noted in other forms of kidney injuries including post-transplant situation. Further research into the role of HSP in prevention of kidney injury is crucial if translation from the laboratory to patient bedside has to occur. This article aims to be a review of heat shock protein, and its relevance to kidney diseases.<\/jats:p>","DOI":"10.1515\/jtim-2016-0034","type":"journal-article","created":{"date-parts":[[2016,12,5]],"date-time":"2016-12-05T10:22:28Z","timestamp":1480933348000},"page":"114-117","source":"Crossref","is-referenced-by-count":25,"title":["The role of heat shock proteins in kidney disease"],"prefix":"10.1515","volume":"4","author":[{"given":"Shobhana","family":"Nayak Rao","sequence":"first","affiliation":[{"name":"Department of Nephrology, K.S Hegde Medical Academy, Medical Sciences Complex, Mangalore, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2016,9,23]]},"reference":[{"key":"2023042508075060143_j_jtim-2016-0034_ref_001_w2aab3b8c20b1b7b1ab2b2b1Aa","doi-asserted-by":"crossref","unstructured":"O\u2019Neill S, Harrison EM. Ross TA, Wignore SJ, Hughes J. Heat -Shock protein and Acute Ischemic Kidney Injury. 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