{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T17:12:53Z","timestamp":1789665173394,"version":"4.0.1"},"reference-count":18,"publisher":"Walter de Gruyter GmbH","issue":"1","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_med-2016-0039_s_384_w2aab3b8d279b1b7b1aab1c14b1Aa\">\n                  <jats:title>Introduction<\/jats:title>\n                  <jats:p>To study the impact on adult\u2019s fertility of serum inhibin B levels in adolescent patients with idiopathic varicocele after minimally invasive surgical correction and to compare fluctuation of pituitary-testis hormonal values and testicular volumes. Materials and Methods: A case-control study was carried out on a group adolescent patients (n=60) affected by idiopathic left varicocele (group V) and compared with control adolescents (n=40) in the Paediatric Surgery Section of Siena (from June 1993 till September 2013). Inhibin B levels and testicular volume before (T0) and after at 6 and 12 months from surgery (T1 and T2) were evaluated. Results: A positive correlation between testicular growth at T1 and T2 (P&lt;0.001) was found. Linear regression analysis showed a positive correlation between inhibin B levels and testicular volume (expressed as the sum of the right and left values) (P&lt;0.0001). Conclusions: Inhibin B levels are a valid marker for studying the effects of varicocele on the testicular function and confirm the necessity of early surgical correction for preventing the trophic testicular damage and male infertility.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/med-2016-0039","type":"journal-article","created":{"date-parts":[[2016,6,27]],"date-time":"2016-06-27T15:56:48Z","timestamp":1467043008000},"page":"204-206","source":"Crossref","is-referenced-by-count":5,"title":["Serum levels of inhibin B in adolescents after varicocelelectomy: A long term follow up"],"prefix":"10.1515","volume":"11","author":[{"given":"Francesco","family":"Molinaro","sequence":"first","affiliation":[{"name":"Division of Pediatric Surgery, Department of Medical, Surgical and Neurological Sciences, University of Siena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisa","family":"Cerchia","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Department of Medical, Surgical and Neurological Sciences, University of Siena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfredo","family":"Garzi","sequence":"additional","affiliation":[{"name":"Department of Medicine and Surgery, Pediatric Surgery, Piazza Sergardi, 16, 52044 Cortona (AR) Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco Maria","family":"Severi","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology, Department of Molecular and Developmental Medicine, University of Siena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rossella","family":"Angotti","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Department of Medical, Surgical and Neurological Sciences, University of Siena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felice","family":"Petraglia","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology, Department of Molecular and Developmental Medicine, University of Siena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Messina","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Department of Medical, Surgical and Neurological Sciences, University of Siena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2016,6,23]]},"reference":[{"key":"2023040102563387157_j_med-2016-0039_ref_001_w2aab3b8d279b1b7b1ab2ab1Aa","doi-asserted-by":"crossref","unstructured":"World Health Organization: The influence of varicocele on parameters of fertility in a large group of men presenting to infertility clinic. Fertil Steril 1992;57;1289-1293","DOI":"10.1016\/S0015-0282(16)55089-4"},{"key":"2023040102563387157_j_med-2016-0039_ref_002_w2aab3b8d279b1b7b1ab2ab2Aa","doi-asserted-by":"crossref","unstructured":"Cheval MJ, Purcell MH. Deteriorations of semen parameters over time in men with untreated varicocele: Evidence of progressive testicular damage. Fertil Steril 1992;57:174-177","DOI":"10.1016\/S0015-0282(16)54796-7"},{"key":"2023040102563387157_j_med-2016-0039_ref_003_w2aab3b8d279b1b7b1ab2ab3Aa","doi-asserted-by":"crossref","unstructured":"Di Bisceglie C, Bertagna A, Baldi M, Lanfranco F, Tagliabue M, Gazzera C, Gandini G, Manieri C. Varicocele sclerotherapy improves serum inhibin B levels and seminal parameters. 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