{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T13:12:05Z","timestamp":1771333925032,"version":"3.50.1"},"reference-count":13,"publisher":"Walter de Gruyter GmbH","issue":"1","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>In Italy, Law 194 of 22 May 1978 provides for and regulates the voluntary termination of pregnancy (VTP). Medical abortion became popular nationwide after Mifepristone (RU-486) was authorized for the market by AIFA (Italian Drug Agency) in July 2009. We searched articles in medical literature database with these terms: \u201cmedical abortion\u201d, \u201cRU486\u201d, \u201csurgical abortion\u201d. We also searched laws and judgments concerning abortion in national legal databases. Ministerial guidelines were searched on official website of Italian Ministry of Health. We found many medical studies about medical and surgical abortion. We found also ministerial and regional guidelines, which were analyzed. From the point of view of legal medicine, the issues related to abortion with the pharmacological method consist in verifying compatibility and consistency with the safety principles and the parameters imposed by Law n. 194 of 1978, using off-label Misoprostol, what inpatient care should be used and informed consent. The doctor\u2019s job is to provide the patient with comprehensive and clear information about how the procedure will be performed, any complications and the time period needed for both procedures.<\/jats:p>","DOI":"10.1515\/med-2016-0062","type":"journal-article","created":{"date-parts":[[2016,8,17]],"date-time":"2016-08-17T08:19:48Z","timestamp":1471421988000},"page":"321-326","source":"Crossref","is-referenced-by-count":13,"title":["Voluntary termination of pregnancy (medical or surgical abortion): forensic medicine issues"],"prefix":"10.1515","volume":"11","author":[{"given":"Mauro","family":"Piras","sequence":"first","affiliation":[{"name":"Department of Surgery, Radiology and Public Health, Public Health and Humanities Section, University of Brescia Italy \u2013 Forensic Medicine Institute, 25123 Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paola","family":"Delbon","sequence":"additional","affiliation":[{"name":"Department of Surgery, Radiology and Public Health, Public Health and Humanities Section, University of Brescia \u2013 Centre of Bioethics Research, 25123 Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paola","family":"Bin","sequence":"additional","affiliation":[{"name":"Department of Surgery, Radiology and Public Health, Public Health and Humanities Section, University of Brescia Italy \u2013 Forensic Medicine Institute, 25123 Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia","family":"Casella","sequence":"additional","affiliation":[{"name":"Department of Advanced Biomedical Sciences, University of Naples \u201cFederico II\u201d, 80131, Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emanuele","family":"Capasso","sequence":"additional","affiliation":[{"name":"Department of Advanced Biomedical Sciences, University of Naples \u201cFederico II\u201d, 80131, Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Massimo","family":"Niola","sequence":"additional","affiliation":[{"name":"Department of Advanced Biomedical Sciences, University of Naples \u201cFederico II\u201d. Via S. Pansini 5, 80131, Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adelaide","family":"Conti","sequence":"additional","affiliation":[{"name":"Department of Surgery, Radiology and Public Health, Public Health and Humanities Section, University of Brescia \u2013 Centre of Bioethics Research, 25123 Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2016,8,13]]},"reference":[{"key":"2023040102562808157_j_med-2016-0062_ref_001_w2aab3b8d191b1b7b1ab2b1b1Aa","unstructured":"Palmieri L., De Ferrari F., Manuale di medicina legale. II ed, Giuffr\u00e8 editore, Milano, 2013"},{"key":"2023040102562808157_j_med-2016-0062_ref_002_w2aab3b8d191b1b7b1ab2b1b2Aa","unstructured":"Giusti G., Trattato di medicina legale e scienze affini, II ed, Padova, ed. CEDAM, 2009"},{"key":"2023040102562808157_j_med-2016-0062_ref_003_w2aab3b8d191b1b7b1ab2b1b3Aa","doi-asserted-by":"crossref","unstructured":"Ashok P.W., Penney G.C., Flett G.M., Templeton A., An effective regimen for early medical abortion: a report of 2000 consecutive cases, Hum Reprod, 1998, 13, 2962-2965","DOI":"10.1093\/humrep\/13.10.2962"},{"key":"2023040102562808157_j_med-2016-0062_ref_004_w2aab3b8d191b1b7b1ab2b1b4Aa","doi-asserted-by":"crossref","unstructured":"Fiala C., Gemzel-Danielsson K., Review of medical abortion using mifepristone in combination with a prostaglandin analogue, Contraception, 2006, 74, 66-86","DOI":"10.1016\/j.contraception.2006.03.018"},{"key":"2023040102562808157_j_med-2016-0062_ref_005_w2aab3b8d191b1b7b1ab2b1b5Aa","doi-asserted-by":"crossref","unstructured":"Elul B., Ellertson C., Winikoff B., Coyaji K., Side effects of mifepristone-misoprostol abortion versus surgical abortion. Data from a trial in China, Cuba and India. Contraception, 1999, 59, 107-114","DOI":"10.1016\/S0010-7824(99)00003-7"},{"key":"2023040102562808157_j_med-2016-0062_ref_006_w2aab3b8d191b1b7b1ab2b1b6Aa","doi-asserted-by":"crossref","unstructured":"Greene M.F., Fatal infections associated with mifepristone induced abortion, N Eng J Med, 2005, 353, 2317-2318","DOI":"10.1056\/NEJMp058260"},{"key":"2023040102562808157_j_med-2016-0062_ref_007_w2aab3b8d191b1b7b1ab2b1b7Aa","doi-asserted-by":"crossref","unstructured":"Lo Woei Chung, Yeh S.P., Hsieh C.Y., Chiu C.F., Thrombotic thrombocytopenic purpura secondary to mifepristone in a patient of medical termination in early pregnancy, Ann Hematol, 2007, 86, 385-386","DOI":"10.1007\/s00277-006-0237-7"},{"key":"2023040102562808157_j_med-2016-0062_ref_008_w2aab3b8d191b1b7b1ab2b1b8Aa","doi-asserted-by":"crossref","unstructured":"Willmot F.J., Scherf C., Ford S.M., Lim K., Rupture of uterus in the first trimester during medical termination of pregnancy for exomphalos using mifepristone\/misoprostol, BJOG, 2008, 115, 1575-1577","DOI":"10.1111\/j.1471-0528.2008.01928.x"},{"key":"2023040102562808157_j_med-2016-0062_ref_009_w2aab3b8d191b1b7b1ab2b1b9Aa","doi-asserted-by":"crossref","unstructured":"Davey A., Mifepristone and prostaglandin for termination of pregnancy: contraindications for use, reasons and rationale, Contraception, 2006, 744, 16-20","DOI":"10.1016\/j.contraception.2006.03.003"},{"key":"2023040102562808157_j_med-2016-0062_ref_010_w2aab3b8d191b1b7b1ab2b1c10Aa","doi-asserted-by":"crossref","unstructured":"Spitz I.M., Bardin C.W., Benton L., Robbins A., Early pregnancy termination with mifepristone and misoprostol in the United States, N Eng J Med, 1998, 338, 1241-1247","DOI":"10.1056\/NEJM199804303381801"},{"key":"2023040102562808157_j_med-2016-0062_ref_011_w2aab3b8d191b1b7b1ab2b1c11Aa","unstructured":"Ministero della Salute. 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