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It has a high mortality rate, up to 40% in the different series, as described in the literature. Surgical and therapeutic management has been discussed for long time especially in an elderly patient population. The literature has been reviewed in order to evaluate different pathogenesis and evolution and to recognise a correct therapeutic management.<\/jats:p>","DOI":"10.1515\/med-2016-0080","type":"journal-article","created":{"date-parts":[[2016,11,19]],"date-time":"2016-11-19T10:02:28Z","timestamp":1479549748000},"page":"449-460","source":"Crossref","is-referenced-by-count":17,"title":["Descending necrotizing mediastinitis in the elderly patients"],"prefix":"10.1515","volume":"11","author":[{"given":"Antonio","family":"Mazzella","sequence":"first","affiliation":[{"name":"Thoracic Surgery Unit, Second University of Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario","family":"Santagata","sequence":"additional","affiliation":[{"name":"Maxillo-Facial Surgery Unit, Second University of Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atirge","family":"Cecere","sequence":"additional","affiliation":[{"name":"Maxillo-Facial Surgery Unit, Second University of Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ettore","family":"La Mart","sequence":"additional","affiliation":[{"name":"Maxillo-Facial Surgery Unit, Second University of Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfonso","family":"Fiorelli","sequence":"additional","affiliation":[{"name":"Thoracic Surgery Unit, Second University of Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianpaolo","family":"Tartaro","sequence":"additional","affiliation":[{"name":"Maxillo-Facial Surgery Unit, Second University of Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Domenico","family":"Tafuri","sequence":"additional","affiliation":[{"name":"Department of Sport Sciences and Wellness, University of Naples \u201cParthenope\u201d, Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Domenico","family":"Testa","sequence":"additional","affiliation":[{"name":"Department of Anesthesiologic, Surgical and Emergency Sciences, Otolaryngology, Head and Neck Surgery Unit, Second University of Naples, Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edoardo","family":"Grella","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Respiratory Sciences, Second University of Naples\/Hosp. 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