{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T21:24:20Z","timestamp":1781904260010,"version":"3.54.5"},"reference-count":23,"publisher":"Walter de Gruyter GmbH","issue":"1","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,9,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_med-2018-0055_s_005_w2aab3b7d226b1b6b1aab1c15b1Aa\">\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Cuffed and uncuffed endotracheal tubes are commonly used for pediatric patients in surgery and emergency situations. It is still controversial which approach should be adopted. The purpose of the study was to compare the application of cuffed and uncuffed endotracheal tubes in pediatric patients.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_med-2018-0055_s_006_w2aab3b7d226b1b6b1aab1c15b2Aa\">\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We searched PubMed, Web of Science and Cochrane Library for clinical trials, which compared the two applications in children. The study characteristics and clinical data were summarized by two independent reviewers. Meta-analysis of the data was done using Revman 5.3 software.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_med-2018-0055_s_007_w2aab3b7d226b1b6b1aab1c15b3Aa\">\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>6 studies with 4141 cases were included in this meta-analysis. The pooling analysis showed that more patients need tube changes in uncuffed than cuffed tubes (OR: 0.07, 95% CI: 0.05-0.10, P &lt; 0.00001). However, there were no differences on intubation duration, reintubation occurrence, accidental extubation rate, croup occurrence and racemic epinephrine use during the intubation process. Also we didn\u2019t find any differences on laryngospasm and stridor occurrence after extubation.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_med-2018-0055_s_008_w2aab3b7d226b1b6b1aab1c15b4Aa\">\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Our study demonstrated that uncuffed endotracheal tubes increased the need for tube changes. Other incidences or complications between the two groups had no differences. Cuffed tubes may be an optimal option for pediatric patients. But more trials are needed in the future.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/med-2018-0055","type":"journal-article","created":{"date-parts":[[2018,9,10]],"date-time":"2018-09-10T10:23:40Z","timestamp":1536575020000},"page":"366-373","source":"Crossref","is-referenced-by-count":34,"title":["Cuffed versus uncuffed endotracheal tubes in pediatrics: a meta-analysis"],"prefix":"10.1515","volume":"13","author":[{"given":"Liang","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Anesthesiology, The Second People\u2019s Hospital of Hefei , Hefei Hospital Affiliated to Medical University of Anhui , No. 246 Heping Road , Hefei , 230011, Anhui Province , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, The Second People\u2019s Hospital of Hefei , Hefei Hospital Affiliated to Medical University of Anhui , No. 246 Heping Road , Hefei , 230011, Anhui Province , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoshi","family":"Pan","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, The Second People\u2019s Hospital of Hefei , Hefei Hospital Affiliated to Medical University of Anhui , No. 246 Heping Road , Hefei , 230011, Anhui Province , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xia","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, The Second People\u2019s Hospital of Hefei , Hefei Hospital Affiliated to Medical University of Anhui , No. 246 Heping Road , Hefei , 230011, Anhui Province , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianwu","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, The Second People\u2019s Hospital of Hefei , Hefei Hospital Affiliated to Medical University of Anhui , No. 246 Heping Road , Hefei , 230011, Anhui Province , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wensheng","family":"He","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, The Second People\u2019s Hospital of Hefei , Hefei Hospital Affiliated to Medical University of Anhui , No. 246 Heping Road , Hefei , 230011, Anhui Province , China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2018,9,8]]},"reference":[{"key":"2022042708343414665_j_med-2018-0055_ref_001_w2aab3b7d226b1b6b1ab2b1b1Aa","doi-asserted-by":"crossref","unstructured":"von Rettberg M, Thil E, Genzwurker H, Gernoth C and Hinkelbein J. 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