{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T21:49:51Z","timestamp":1769032191275,"version":"3.49.0"},"reference-count":16,"publisher":"Walter de Gruyter GmbH","issue":"1","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,12,17]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_med-2019-0112_s_004\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Cardiac arrest related to nerve blockade using a local anaesthetic is a rare event. We report a case of bupivacaine severe cardiovascular toxicity following cervical paravertebral nerve block.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_med-2019-0112_s_005\">\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>A 44-year-old female was admitted to Republican Vilnius University Hospital, with symptoms of sustained severe pain in her neck that radiated to both arms. Multiple cervical intervertebral hernias with spinal stenosis were confirmed by magnetic resonance imaging. Following infiltration of the subcutaneous tissue with a 0.5 % bupivacaine solution, an 18-gauge spinal needle was used to perform the paravertebral block at the C6 level. Bupivacaine was injected in incremental doses to a total of 10 mL. Rapid loss of consciousness and cardiovascular collapse suggested a neuraxial injection of bupivacaine. Long-lasting cardiopulmonary resuscitation, including chest compressions, defibrillation attempts for refractory ventricular fibrillation, medications, mechanical ventilation, and intravenous lipid emulsion infusion, was successful. No severe adverse outcomes other than acute kidney injury and chest pain related to prolonged chest compressions were documented.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_med-2019-0112_s_006\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This case report emphasizes the necessity of ensuring adequate safety precautions to avoid local anaesthetic systemic toxicity. Lipid emulsion preparations should be available in all hospital settings where local anaesthetics are used for regional anaesthesia or pain management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1515\/med-2019-0112","type":"journal-article","created":{"date-parts":[[2019,12,18]],"date-time":"2019-12-18T04:03:08Z","timestamp":1576641788000},"page":"953-958","source":"Crossref","is-referenced-by-count":4,"title":["Resuscitation following a bupivacaine injection for a cervical paravertebral block"],"prefix":"10.1515","volume":"14","author":[{"given":"Saulius","family":"Vosylius","sequence":"first","affiliation":[{"name":"Clinic of Anaesthesiology and Intensive Care, Faculty of Medicine, Vilnius University, Republican Vilnius University Hospital , Siltnamiu 29 , Vilnius, LT-04130 , Vilnius , Lithuania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valentinas","family":"Uvarovas","sequence":"additional","affiliation":[{"name":"Clinic of Rheumatology, Orthopaedic Traumatology and Reconstructive Surgery, Faculty of Medicine, Vilnius University , Siltnamiu 29 , Vilnius, LT-04130 , Vilnius , Lithuania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saul\u0117","family":"Svediene","sequence":"additional","affiliation":[{"name":"Clinic of Anaesthesiology and Intensive Care, Faculty of Medicine, Vilnius University, Republican Vilnius University Hospital , Siltnamiu 29 , Vilnius, LT-04130 , Vilnius , Lithuania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Igoris","family":"Satkauskas","sequence":"additional","affiliation":[{"name":"Clinic of Rheumatology, Orthopaedic Traumatology and Reconstructive Surgery, Faculty of Medicine, Vilnius University , Siltnamiu 29 , Vilnius, LT-04130 , Vilnius , Lithuania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2019,12,17]]},"reference":[{"key":"2026012107370038759_j_med-2019-0112_ref_001","doi-asserted-by":"crossref","unstructured":"Vasques F., Behr A.U., Weinberg G., Ori C., Di Gregorio G. 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