{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T18:54:04Z","timestamp":1791572044710,"version":"4.3.4"},"reference-count":20,"publisher":"Walter de Gruyter GmbH","issue":"1","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,10,13]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Ultrasound-guided erector spinae plane block (ESPB) was originally developed for the treatment of neuropathic chest pain and has since been used in various thoracic, lumbar, and sacral surgeries.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aimed to establish whether unilateral or bilateral ESPB is more effective for pain management in laparoscopic cholecystectomy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>A total of 54 adult patients undergoing laparoscopic cholecystectomy were divided into three groups: unilateral ESPB, bilateral ESPB, and a control group (no ESPB). The unilateral ESPB group received 20\u2009mL of 0.25% bupivacaine preoperatively at the T8 vertebral level. The bilateral ESPB group received 20\u2009mL of 0.25% bupivacaine to both sides of the vertebra. The control group received no intervention, and all three groups received general anesthesia. Intraoperatively, all patients received 50\u2009mg of dexketoprofen and 1\u2009mg\/kg of tramadol. Postoperative tramadol use and visual analog scale (VAS) scores were recorded at 0\u2009min, 30\u2009min, 2\u2009h, 6\u2009h, 12\u2009h, and 24\u2009h.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Demographic characteristics did not differ significantly between the groups. At the 6\u2009h post-surgery, the VAS scores in the bilateral ESPB group were significantly lower than the control group (\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.001). Total tramadol use in 24\u2009h was significantly lower in the bilateral ESPB group compared with the control group (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.003).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Bilateral ESPB could be a valuable component of multimodal analgesia strategies in laparoscopic cholecystectomies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1515\/med-2025-1268","type":"journal-article","created":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T12:04:53Z","timestamp":1760443493000},"source":"Crossref","is-referenced-by-count":1,"title":["Ultrasound-guided unilateral versus bilateral erector spinae plane block for postoperative analgesia of patients undergoing laparoscopic cholecystectomy"],"prefix":"10.1515","volume":"20","author":[{"given":"Ay\u00e7a Tuba","family":"Dumanl\u0131 \u00d6zcan","sequence":"first","affiliation":[{"name":"Bilkent City Hospital, University of Health Sciences , Ankara , T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuf","family":"Y\u0131lmaz","sequence":"additional","affiliation":[{"name":"Anesthesiology and Reanimation, Ankara Bilkent City Hospital , Ankara , T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa","family":"Turan","sequence":"additional","affiliation":[{"name":"Anesthesiology and Reanimation, Ankara Bilkent City Hospital , Ankara , T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erdal","family":"\u00d6zcan","sequence":"additional","affiliation":[{"name":"Bilkent City Hospital, University of Health Sciences , Ankara , T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ezgi","family":"Erk\u0131l\u0131\u00e7","sequence":"additional","affiliation":[{"name":"Anesthesiology and Reanimation, Ankara Bilkent City Hospital , Ankara , T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Handan","family":"G\u00fcle\u00e7","sequence":"additional","affiliation":[{"name":"Anesthesiology and Reanimation Department, Ankara Y\u0131ld\u0131r\u0131m Beyaz\u0131t University , Ankara , T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2025,10,13]]},"reference":[{"key":"2026100918221197199_j_med-2025-1268_ref_001","doi-asserted-by":"crossref","unstructured":"Forero M, Adhikary SD, Lopez H, Tsui C, Chin KJ. 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