{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T13:20:08Z","timestamp":1784035208739,"version":"3.55.0"},"reference-count":24,"publisher":"Walter de Gruyter GmbH","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"The High-level innovative talents of Guizhou Province","award":["GCC [2023]081"],"award-info":[{"award-number":["GCC [2023]081"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["82260254"],"award-info":[{"award-number":["82260254"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Zunyi Science and Technology Project","award":["Zunshi Kehe HZ [2023]218"],"award-info":[{"award-number":["Zunshi Kehe HZ [2023]218"]}]},{"name":"Peking Union Medical College RuiE Emergency Medicine Research Fund","award":["PUMF01010010-2024-23"],"award-info":[{"award-number":["PUMF01010010-2024-23"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,23]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_med-2026-1458_abs_001\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Acute organophosphorus pesticide poisoning (AOPP) constitutes a common yet life-threatening emergency, particularly prevalent in rural regions of Asia. The condition results from inhibited cholinesterase activity, which induces acetylcholine accumulation at neural synapses. Clinically, its manifestations are categorized into muscarinic, nicotinic, and central types. Among these, mortality typically arises from respiratory paralysis, while neurological sequelae are frequently encountered. Nevertheless, reports of AOPP-induced intestinal necrosis remain\u00a0exceedingly uncommon both domestically and internationally.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_med-2026-1458_abs_002\">\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>In the present case, the patient experienced acute poisoning following oral ingestion of a high dose of dichlorvos. Despite initial standardized management, including atropine administration, pralidoxime therapy, and hemoperfusion, complications such as toxic encephalopathy and multiple organ dysfunction ensued. During hospitalization, acute peritonitis developed, and abdominal computed tomography revealed intestinal perforation accompanied by peritonitis. Exploratory laparotomy confirmed small intestinal necrosis and perforation of the ascending colon, necessitating resection of the necrotic segment and enterostomy. Postoperatively, the patient was transferred to the emergency intensive care unit for comprehensive supportive treatment and subsequently achieved full recovery before discharge.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_med-2026-1458_abs_003\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This case highlights that in patients with severe organophosphorus poisoning, any unexplained alteration in abdominal signs should prompt high clinical suspicion of gastrointestinal complications, and prompt surgical intervention may be lifesaving. However, as a single case report, this study carries inherent limitations, and future large-scale investigations remain essential to further substantiate these findings and develop more effective therapeutic strategies to enhance the overall management of\u00a0AOPP.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1515\/med-2026-1458","type":"journal-article","created":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T12:56:21Z","timestamp":1784033781000},"source":"Crossref","is-referenced-by-count":0,"title":["Successful treatment of acute organophosphorus pesticide poisoning complicated by intestinal necrosis with exploratory laparotomy: a case report"],"prefix":"10.1515","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-5240-579X","authenticated-orcid":false,"given":"Shuhong","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Emergency , Affiliated Hospital of Zunyi Medical University , Zunyi , Guizhou , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-1529-7462","authenticated-orcid":false,"given":"Lili","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Emergency , Affiliated Hospital of Zunyi Medical University , Zunyi , Guizhou , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-0514-6459","authenticated-orcid":false,"given":"Yin","family":"Tian","sequence":"additional","affiliation":[{"name":"Department of Cardiology , The First People\u2019s Hospital of Zunyi , Zunyi , Guizhou , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Emergency , Affiliated Hospital of Zunyi Medical University , Zunyi , Guizhou , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-4756-3105","authenticated-orcid":false,"given":"Xiangui","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Emergency , Affiliated Hospital of Zunyi Medical University , Zunyi , Guizhou , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-5155-2481","authenticated-orcid":false,"given":"Ruilie","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Emergency , Affiliated Hospital of Zunyi Medical University , Zunyi , Guizhou , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-4091-9612","authenticated-orcid":false,"given":"Yuanlan","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Emergency , Affiliated Hospital of Zunyi Medical University , Zunyi , Guizhou , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anyong","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Emergency , Affiliated Hospital of Zunyi Medical University , Zunyi , Guizhou , China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2026,7,14]]},"reference":[{"key":"2026071412561945310_j_med-2026-1458_ref_001","doi-asserted-by":"crossref","unstructured":"Eddleston, M, Phillips, MR. 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