{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T13:46:08Z","timestamp":1791812768050,"version":"4.3.4"},"reference-count":27,"publisher":"Walter de Gruyter GmbH","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,23]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_med-2026-1524_abs_001\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate, among premenopausal women with endometrial polyps and documented dysmenorrhea, whether levonorgestrel-releasing intrauterine system (LNG-IUS) placement after hysteroscopic polypectomy (HP) was associated with better outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_med-2026-1524_abs_002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective cohort study analyzed 276 premenopausal women with pathologically confirmed endometrial polyps who underwent HP between January 2022 and December 2024. Patients were classified into an HP-alone group (n=162) or an HP+LNG-IUS group (n=114).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_med-2026-1524_abs_003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>At 12\u00a0months, the HP+LNG-IUS group had lower VAS scores than the HP group (aMD=\u22120.36; 95\u202f% CI,\u00a0\u22120.60 to\u00a0\u22120.12; p=0.004). Clinically meaningful dysmenorrhea improvement occurred in 79.82\u202f% in the HP+LNG-IUS group and 65.43\u202f% in the HP group (aOR, 2.22; 95\u202f% CI, 1.23\u20133.99; p=0.008). HP+LNG-IUS was also associated with a lower 12-month PBAC score and thinner endometrium. Exploratory analyses showed lower measured FSH, LH, estradiol, and progesterone levels. Polyp recurrence was observed in 2.63\u202f% in the HP+LNG-IUS group and 9.26\u202f% in the HP\u00a0group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_med-2026-1524_abs_004\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this study, LNG-IUS placement after HP was associated with modestly lower pain scores, lower menstrual blood loss, thinner endometrium, and lower observed 12-month polyp recurrence. Residual confounding, sparse recurrence events, ultrasound-based recurrence ascertainment, and retrospective adverse-event capture limit causal and safety inferences. Prospective controlled studies are required.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1515\/med-2026-1524","type":"journal-article","created":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T12:56:29Z","timestamp":1791809789000},"source":"Crossref","is-referenced-by-count":0,"title":["Hysteroscopic polypectomy with vs. without levonorgestrel-releasing intrauterine system in women with endometrial polyps and dysmenorrhea"],"prefix":"10.1515","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-5729-4664","authenticated-orcid":false,"given":"Yongyan","family":"Ni","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Jiangsu Province Academy of Traditional Chinese Medicine , Nanjing , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0886-2425","authenticated-orcid":false,"given":"Yue","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Jiangsu Province Academy of Traditional Chinese Medicine , Nanjing , China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2026,10,12]]},"reference":[{"key":"2026101212562029520_j_med-2026-1524_ref_001","doi-asserted-by":"crossref","unstructured":"Luo, A, Shen, W, Lv, X, Yang, S. 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