{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T14:29:25Z","timestamp":1762352965083,"version":"build-2065373602"},"reference-count":30,"publisher":"Walter de Gruyter GmbH","issue":"5","license":[{"start":{"date-parts":[[2025,8,19]],"date-time":"2025-08-19T00:00:00Z","timestamp":1755561600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"DOI":"10.13039\/501100009592","name":"Beijing Municipal Science & Technology Commission","doi-asserted-by":"crossref","award":["Z191100006619002"],"award-info":[{"award-number":["Z191100006619002"]}],"id":[{"id":"10.13039\/501100009592","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Capital Institute of Pediatrics","award":["LCYJ-2023-22"],"award-info":[{"award-number":["LCYJ-2023-22"]}]},{"name":"Haiyou Health High-Caliber Talent Project","award":["202412"],"award-info":[{"award-number":["202412"]}]},{"name":"Research Unit of Minimally Invasive Pediatric Surgery on Diagnosis and Treatment, Chinese Academy of Medical Sciences","award":["2021RU015"],"award-info":[{"award-number":["2021RU015"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,10,28]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_mr-2025-0024_abs_001\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Kasai portoenterostomy (KPE) is the primary treatment for biliary atresia (BA). However, postoperative complications such as cholangitis with bile lake formation frequently lead to liver failure. This study aimed to evaluate the therapeutic efficacy and significance of revision portoenterostomy in patients with bile lakes at the porta hepatis following\u00a0KPE.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_mr-2025-0024_abs_002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective analysis of patients with BA who underwent revision portoenterostomy from January 2011 to December 2021 was conducted. Patient data, including laboratory tests, imaging findings, and follow-up records, were comprehensively reviewed. The jaundice clearance rate and autologous liver survival rate were assessed using the Kaplan\u2013Meier method. The Cox proportional hazards model was employed to identify factors influencing revision portoenterostomy outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_mr-2025-0024_abs_003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Twenty patients with cholangitis and bile lakes underwent revision portoenterostomy. Sixteen patients (80\u202f%) achieved jaundice clearance, and 14 (60\u202f%) attained autologous liver survival, resulting in an overall survival rate of 90\u202f%. All patients with refractory cholangitis preoperatively showed improvement following revision portoenterostomy. Additionally, the revision portoenterostomy procedure did not lead to increased blood loss or extended operation times in subsequent liver transplants.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_mr-2025-0024_abs_004\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Revision portoenterostomy for patients with bile lakes effectively alleviates intractable cholangitis and can delay or eliminate the necessity for liver transplantation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1515\/mr-2025-0024","type":"journal-article","created":{"date-parts":[[2025,8,18]],"date-time":"2025-08-18T13:56:25Z","timestamp":1755525385000},"page":"412-420","source":"Crossref","is-referenced-by-count":0,"title":["Outcomes of revised portoenterostomy for postoperative bile lakes in patients with biliary atresia"],"prefix":"10.1515","volume":"5","author":[{"given":"Yu","family":"Tian","sequence":"first","affiliation":[{"name":"Department of Pediatric Surgery, Capital Center for Children\u2019s Health , Capital Medical University , Beijing , China"},{"name":"Department of Pediatric Surgery , 36776 Capital Institute of Pediatrics-Peking University Teaching Hospital , Beijing , China"},{"name":"Precision Regenerative Medicine Research Centre, Medical Science Division, and State Key Laboratory of Quality Research in Chinese Medicine , Macau University of Science and Technology , Macao , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiayi","family":"Feng","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery , Kunming Children\u2019s Hospital\/ Kunming Medical University , Kunming , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mao","family":"Ye","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Capital Center for Children\u2019s Health , Capital Medical University , Beijing , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhen","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Capital Center for Children\u2019s Health , Capital Medical University , Beijing , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuanyuan","family":"Geng","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Capital Center for Children\u2019s Health , Capital Medical University , Beijing , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaojin","family":"He","sequence":"additional","affiliation":[{"name":"Department of Pharmacy , 36776 Affiliated Children\u2019s Hospital of the Capital Institute of Pediatrics , Beijing , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuai","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery , Children\u2019s Hospital Affiliated to Shandong University (Jinan Children\u2019s Hospital) , Jinan , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xu","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Capital Center for Children\u2019s Health , Capital Medical University , Beijing , China"},{"name":"Research Unit of Minimally Invasive Pediatric Surgery on Diagnosis and Treatment, Chinese Academy of Medical Sciences , Beijing , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0358-3929","authenticated-orcid":false,"given":"Long","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Capital Center for Children\u2019s Health , Capital Medical University , Beijing , China"},{"name":"Research Unit of Minimally Invasive Pediatric Surgery on Diagnosis and Treatment, Chinese Academy of Medical Sciences , Beijing , China"},{"name":"Department of Pediatric Surgery , Beijing Tsinghua Changgung Hospital , Beijing , China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2025,8,19]]},"reference":[{"key":"2025110514123147744_j_mr-2025-0024_ref_001","doi-asserted-by":"crossref","unstructured":"Tam, PKH, Wells, RG, Tang, CSM, Lui, VCH, Hukkinen, M, Luque, CD, et al.. 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