{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T02:41:25Z","timestamp":1784860885302,"version":"3.55.0"},"reference-count":56,"publisher":"Walter de Gruyter GmbH","issue":"3","license":[{"start":{"date-parts":[[2017,9,26]],"date-time":"2017-09-26T00:00:00Z","timestamp":1506384000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,9,26]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The aim of this study was to assess cardiac disorders in dogs infected with B. canis. The study included 50 dogs with babesiosis and 20 healthy control animals. All the animals had haematological tests, ECG, echocardiography and serum troponin I and CK-MB levels checked. The haematology in the group of dogs with babesiosis confirmed thrombocytopaenia in 100% of dogs, decreased haematocrit in 52% and anaemia in 46%. The most common abnormalities in ECG and echocardiography in dogs infected with protozoa included: change in appearance and\/or amplitude of the T-wave (34%), increased fractional shortening (24%), an increased sinus rhythm (14%) and heart axis deviation (10%). In 19 of the 50 dogs with babesiosis, the level of serum troponin I was elevated. In 2 dogs that died from babesiosis, the troponin level I was very high. The ECG confirmed sinus tachycardia and interpolated ventricular beat in these animals. In all dogs with babesiosis that were used in the study, the serum CK-MB was high or very high and was within limits of 23.17 U\/L - 369.62 U\/L. The highest kinase concentration (367.33 U\/L and 369.62 U\/L) was observed in dogs that died due to the disease. The presented results prove that cardiac changes are common in canine babesiosis, but that most changes are nonspecific and appear to have little clinical significance. Cardiovascular assessment should be based on the assessment of the level of troponin I and CK-MB in the serum of sick animals. High concentrations of these factors might be indicators of poor prognosis.<\/jats:p>","DOI":"10.1515\/pjvs-2017-0070","type":"journal-article","created":{"date-parts":[[2017,11,22]],"date-time":"2017-11-22T22:16:29Z","timestamp":1511388989000},"page":"573-581","source":"Crossref","is-referenced-by-count":22,"title":["Cardiac disorders in dogs infected with Babesia canis"],"prefix":"10.1515","volume":"20","author":[{"given":"M.","family":"Bartnicki","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"\u0141yp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"D\u0119biak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Staniec","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Winiarczyk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Buczek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u0141.","family":"Adaszek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","reference":[{"key":"ref51","first-page":"138","article-title":"Canine babesiosis in","author":"Bourdoiseau","year":"2006","journal-title":"Vet Parasitol"},{"key":"ref431","first-page":"23","article-title":"The pathophysiology of renal and cardiac changes in canine babesiosis : Pathophysiology of canine babesiosis LAP Lambert Academic Publishing","author":"Lobetti","year":"2010"},{"key":"ref481","first-page":"2333","article-title":"Differential reactivity of cardiac and skeletal muscle from various species in a cardiac troponin immunoassay","author":"Brien","year":"1997","journal-title":"Clin Chem"},{"key":"ref551","first-page":"544","article-title":"Zahler Schein Rinder Characteristic genotypes discriminate between Babesia canis isolates of differing vector specificity and pathogenicity to dogs","author":"Gothe","year":"1998","journal-title":"Parasitol Res"},{"key":"ref121","first-page":"15","article-title":"Electrocardiographic changes and cardiac pathology in canine babesiosis Vet","volume":"6","author":"Dvir","year":"2004"},{"key":"ref421","first-page":"1","article-title":"Canine babesiosis : from molecular taxonomy to control Vectors of the small canine piroplasms from California : Babesia conradae in the literature","author":"Irwin","year":"2009","journal-title":"Parasit AM review Vet Parasitol"},{"key":"ref401","first-page":"15","article-title":"Electrocardiographic changes and cardiac pathology in canine babesiosis Vet","volume":"6","author":"Dvir","year":"2004"},{"key":"ref181","first-page":"157","article-title":"Molecular detection of sp in African wild dogs pictus in South Africa","author":"Matjila","year":"2008","journal-title":"Vet Parasitol"},{"key":"ref531","first-page":"358","article-title":"Changes in echocardiographic variables of left ventricular size and function in a model of canine normovolemic anemia Vet Ultrasound","author":"Spotswood","year":"2006"},{"key":"ref31","first-page":"950","article-title":"Myocardial infarction redefined - a consensus document of The Joint European Society of Cardiology College of Cardiology Committee for the redefinition of myocardial infraction","author":"Alpert","year":"2000","journal-title":"American J Am Coll Cardiol"},{"key":"ref281","first-page":"81","article-title":"The clinical course of babesiosis in dogs infected with protozoa parasites Babesia canis canis","volume":"12","author":"Adaszek","year":"2009","journal-title":"Pol J Vet Sci"},{"key":"ref321","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1111\/j.1748-5827.2007.00510.x","article-title":"The diagnostic accuracy of different natriuretic peptides in the investigation of canine cardiac disease","volume":"49","author":"Boswood","year":"2008","journal-title":"J Small Anim Pract"},{"key":"ref191","doi-asserted-by":"crossref","first-page":"220","DOI":"10.2307\/3280808","article-title":"Light electron microscopic study on developmental stages of Babesia canis within the gut of the tick Dermacentor reticulatus","author":"Mehlhorn","year":"1980","journal-title":"J Parasitol"},{"key":"ref141","first-page":"1","article-title":"Canine babesiosis : from molecular taxonomy to control Vectors of the small canine piroplasms from California : Babesia conradae in the literature","author":"Irwin","year":"2009","journal-title":"Parasit AM review Vet Parasitol"},{"key":"ref501","first-page":"4","article-title":"Why is Southern African canine babesiosis so virulent ? 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