{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T11:06:11Z","timestamp":1765278371412,"version":"3.46.0"},"reference-count":3,"publisher":"Walter de Gruyter GmbH","issue":"2","license":[{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,6,26]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n This case report aims to describe the impact of the bidirectional chemotherapy (BDC) on resecability for initially unresectable malignant peritoneal mesothelioma (MPM).<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n We report a case of 55-year-old male with the diagnosis of initially unresecable MPM. The BDC combined intravenous (IV) chemotherapy (Cisplatin\u2013Pemetrexed) and intra peritoneal (IP) chemotherapy (Cisplatin). The response to chemotherapy was assessed by CT \u2013 scan and laparoscopy.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n Initial evaluation classed the disease as unresecable with PCI at 39. At the reevaluation, CT \u2013 scan and laparoscopy showed a macroscopic response, allowing surgery consisting of cytoreductive surgery and hyperthermic intra peritoneal chemotherapy (Doxorubicin and Cisplatin).<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n BDC (IV and IP) has promising results and allows to undergo surgery for selected patients with borderline or initially unresectable MPM.<\/jats:p>\n <\/jats:sec>","DOI":"10.1515\/pp-2019-0011","type":"journal-article","created":{"date-parts":[[2019,6,21]],"date-time":"2019-06-21T05:03:21Z","timestamp":1561093401000},"source":"Crossref","is-referenced-by-count":1,"title":["Bidirectional chemotherapy allowing surgery and HIPEC for malignant peritoneal mesothelioma"],"prefix":"10.1515","volume":"4","author":[{"given":"Barbara","family":"Noiret","sequence":"first","affiliation":[{"name":"Department of Digestive and Oncologic Surgery, Claude Huriez University Hospital, Centre Hospitalier Universitaire (CHU) Lille, Universit\u00e9 de Lille , Lille , France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clarisse","family":"Eveno","sequence":"additional","affiliation":[{"name":"Department of Digestive and Oncologic Surgery, Claude Huriez University Hospital, Centre Hospitalier Universitaire (CHU) Lille, Universit\u00e9 de Lille; INSERM Unit\u00e9 Mixte de Recherche 1172-JPARC Jean-Pierre Aubert Research Center, Team \u201cMucins, epithelial differentiation, and carcinogenesis\u201d , Lille , France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2019,6,21]]},"reference":[{"key":"2025120909240995028_j_pp-2019-0011_ref_001_w2aab3b7b3b1b6b1ab1b6b1Aa","doi-asserted-by":"crossref","unstructured":"Sugarbaker PH. Update on the management of malignant peritoneal mesothelioma. Transl Lung Cancer Res. 2018;7:599\u2013608.10.21037\/tlcr.2018.08.0330450299","DOI":"10.21037\/tlcr.2018.08.03"},{"key":"2025120909240995028_j_pp-2019-0011_ref_002_w2aab3b7b3b1b6b1ab1b6b2Aa","doi-asserted-by":"crossref","unstructured":"Le Roy F, Gelli M, Hollebecque A, Honor\u00e9 C, Boige V, Dartigues P, et al. Conversion to complete cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for malignant peritoneal mesothelioma after bidirectional chemotherapy. Ann Surg Oncol. 2017;24:3640\u20136.2884938910.1245\/s10434-017-6033-x","DOI":"10.1245\/s10434-017-6033-x"},{"key":"2025120909240995028_j_pp-2019-0011_ref_003_w2aab3b7b3b1b6b1ab1b6b3Aa","doi-asserted-by":"crossref","unstructured":"Giger-Pabst U, Demtr\u00f6der C, Falkenstein TA, Ouaissi M, G\u00f6tze TO, Rezniczek GA, et al. Pressurized intraperitoneal aerosol chemotherapy (PIPAC) for the treatment of malignant mesothelioma. BMC Cancer. 2018;18:442.2966952410.1186\/s12885-018-4363-0","DOI":"10.1186\/s12885-018-4363-0"}],"container-title":["Pleura and Peritoneum"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.degruyter.com\/view\/journals\/pp\/4\/2\/article-20190011.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1515\/pp-2019-0011\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1515\/pp-2019-0011\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T11:01:19Z","timestamp":1765278079000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1515\/pp-2019-0011\/html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,1]]},"references-count":3,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2019,6,28]]},"published-print":{"date-parts":[[2019,6,26]]}},"alternative-id":["10.1515\/pp-2019-0011"],"URL":"https:\/\/doi.org\/10.1515\/pp-2019-0011","relation":{},"ISSN":["2364-768X","2364-7671"],"issn-type":[{"type":"electronic","value":"2364-768X"},{"type":"print","value":"2364-7671"}],"subject":[],"published":{"date-parts":[[2019,6,1]]},"article-number":"20190011"}}